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Author: Iqbal Ahmad Publisher: Springer Science & Business Media ISBN: 364212173X Category : Medical Languages : en Pages : 549
Book Description
Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.
Author: Iqbal Ahmad Publisher: Springer Science & Business Media ISBN: 364212173X Category : Medical Languages : en Pages : 549
Book Description
Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.
Author: Wilfred Vermerris Publisher: Springer Science & Business Media ISBN: 1402051646 Category : Science Languages : en Pages : 284
Book Description
These are just a few examples that illustrate the chemical diversity and use of phenolic compounds, the topic of ‘Phenolic Compound Biochemistry’. This book is written for researchers, instructors, advanced undergraduate students and beginning graduate students in the life sciences who wish to become more familiar with these and many other intriguing aspects of phenolic compounds. Topics covered include nomenclature, chemical properties, biosynthesis, including an up-to-date overview of the genetics controlling phenolic metabolism, isolation and characterization of phenolic compounds, phenolics used in plant defense, and the impact of phenolics on human health. The book is written in an accessible style, and assumes only basic knowledge of organic chemistry, biochemistry and cell physiology. More than 300 chemical structures and reaction schemes illustrate the text. Wilfred Vermerris is Associate Professor of Agronomy at the University of Florida Genetics Institute in Gainesville, FL. His research focuses on the genetic control of phenolic compounds that impact agro-industrial processing of crop plants. Ralph Nicholson is Professor of Botany and Plant Pathology at Purdue University in West Lafayette, IN. He is an expert on phenolic compounds involved in the plant’s defense against pathogenic fungi and bacteria.
Author: WHO Regional Office for the Western Pacific Publisher: World Health Organization ISBN: 9789290616320 Category : Medical Languages : en Pages : 0
Book Description
This volume, one in a series on medicinal plants in Member States of WHO's Western Pacific Region, introduces Mongolian traditional medicine and details the nature and uses of medicinal plants found in the country. The book focuses on the medicinal plants used most commonly in Mongolia. Each monograph contains color pictures of the plant and a wide array of information--from the scientific and English names of plants to their microscopic characteristics. While helping record and document traditional medicine practices, this book contributes to the understanding of the value of medicinal plants in Mongolia and increases the evidence base for the safe and efficacious use of herbs in health care.
Author: P. N. Ravindran Publisher: CRC Press ISBN: 1420023365 Category : Health & Fitness Languages : en Pages : 573
Book Description
Ginger: The Genus Zingiber is the first comprehensive volume on ginger. Valued as a spice and medicinal plant from ancient times both in India and China, ginger is now used universally as a versatile spice and in traditional medicine as well as in modern medicine. This book covers all aspects of ginger, including botany, crop improvement, chemistry
Author: John T. Arnason Publisher: Springer Science & Business Media ISBN: 1489917780 Category : Science Languages : en Pages : 369
Book Description
Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.
Author: Prof. Dr. N. Raaman Publisher: New India Publishing Agency ISBN: 939017595X Category : Technology & Engineering Languages : en Pages : 12
Book Description
Phytochemicals are the individual chemicals from which the plants are made and plants are the key sources of raw materials for both pharmaceutical and aromatic industries. The improved methods for higher yield of active compounds will be the major incentive in these industries. To help those who involved in the isolation of compounds from plants, some of the essential phytochemical techniques are included in this book. It contains 10 chapters. A brief introduction is given in Chapter 1. Chapter 2 deals with the production processes for herbals and botanicals. Selection of plant and plant parts for phytochemical analysis are included in Chapter 3. Different methods of extraction are given in Chapter 4. Qualitative phytochemical screening is presented in Chapter 5. Various methods for separation of phytochemicals, which include paper and thin layer chromatography and column chromatography are given in Chapter 6. Qualitative and quantitative estimation of phytochemicals using gas chromatography, high performance liquid chromatography and high performance thin layer chromatography are described in Chapter 7. The various methods of identification including the physical characteristics and spectroscopy are included in Chapter 8. The ultraviolet spectroscopy, infrared spectroscopy, near infrared spectroscopy, mass spectroscopy, nuclear magnetic resonance spectroscopy and crystallography are included in this chapter. The categories of phytochemicals are given in Chapter 9. A case study of isolation and identification of compounds in the laboratory of the author of this book is included in Chapter 10. Isolation of alkaloids is given in Chapter 11. Extraction and isolation of phenolic compounds is described in Chapter 12. Isolation of anthocyanin compounds is included in Chapter 13. Extraction and analysis of essential oils are described in Chapter 14. The theoretical principles involved in the instruments, handling of samples and interpretation of spectra are given in detail. More than 160 figures (27 in colour) are included to illustrate the various techniques and the structures of compounds. Apart from the references, indexes of common and scientific names of plants and chemical names and subject index are included.
Author: Aisha Saleem Khan Publisher: Springer ISBN: 3319567772 Category : Science Languages : en Pages : 313
Book Description
This book provides researchers and advanced students associated with plant and pharmaceutical sciences with comprehensive information on medicinal trees, including their identification, morphological characteristics, traditional and economic uses, along with the latest research on their medicinal compounds. The text covers the ecological distribution of over 150 trees, which are characterized mainly on the basis of their unique properties and phytochemicals of medicinal importance (i.e., anti-allergic, anti-diabetic, anti-carcinogenic, anti-microbial, and possible anti-HIV compounds). Due to the incredibly large diversity of medicinal trees, it is not possible to cover all within one publication, so trees with unique medicinal properties that are relatively more common in many countries are discussed here in order to make it most informative for a global audience. With over 100 illustrations taken at different stages of plant development, this reference work serves as a tool for tree identification and provides morphological explanations. It includes the latest botanical research, including biochemical advancements in phytochemistry techniques such as chromatographic and spectrometric techniques. In addition, the end of each chapter presents the most up-to-date references for further sources of exploration.
Author: Nikhil Malhotra Publisher: Academic Press ISBN: 012823430X Category : Science Languages : en Pages : 436
Book Description
The Himalayan Region is a mega hot spot for biological diversity. It supports over 1,748 plants species of known medicinal value. This title focuses on origin and distribution of Himalayan herbs, their medicinal potential, industrial significance, and research advancements pertaining to molecular breeding and omics-based approaches. - Discusses evolved secondary biochemical pathways often in response to specific environmental stimuli - Reviews conservation efforts - Presents an in-depth analysis of 12 key species
Author: Christophe Wiart Publisher: CRC Press ISBN: 1420006800 Category : Health & Fitness Languages : en Pages : 335
Book Description
Drawing on the author's extensive personal experience, Medicinal Plants of Asia and the Pacific provides comprehensive coverage of the medicinal plants of the region. Describing more than 300 compounds, the book discusses every important class of natural products while highlighting cutting-edge research and recent developments. With its broa
Author: Maurice M. Iwu Publisher: CRC Press ISBN: 1466571985 Category : Health & Fitness Languages : en Pages : 446
Book Description
With over 50,000 distinct species in sub-Saharan Africa alone, the African continent is endowed with an enormous wealth of plant resources. While more than 25 percent of known species have been used for several centuries in traditional African medicine for the prevention and treatment of diseases, Africa remains a minor player in the global natural
Author: Iqbal Ahmad
Author: Iqbal Ahmad
Author: Wilfred Vermerris
Author: WHO Regional Office for the Western Pacific
Author: P. N. Ravindran
Author: John T. Arnason
Author: Prof. Dr. N. Raaman
Author: Aisha Saleem Khan
Author: Nikhil Malhotra
Author: Christophe Wiart
Author: Maurice M. Iwu