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Author: Esteban Domingo Publisher: Academic Press ISBN: 0128163321 Category : Science Languages : en Pages : 428
Book Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes
Author: Christian R. Landry Publisher: Springer Science & Business Media ISBN: 9400773471 Category : Science Languages : en Pages : 358
Book Description
Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.
Author: Esteban Domingo Publisher: Academic Press ISBN: 0128163321 Category : Science Languages : en Pages : 428
Book Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes
Author: National Research Council Publisher: National Academies Press ISBN: 0309038405 Category : Science Languages : en Pages : 128
Book Description
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309133815 Category : Social Science Languages : en Pages : 384
Book Description
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Author: John G. Scandalios Publisher: Academic Press ISBN: 148327022X Category : Science Languages : en Pages : 293
Book Description
Physiological Genetics is a compilation of developments, contributed by experts in the field of physiological genetics. The articles contained in the book covers various accounts of developments in the field. The book starts with an introductory chapter describing genetic factors in developmental gene regulation, followed by discussions on enzyme differentiation, hormonal control of gene expression, biochemical genetics of morphogenesis, cytoplasmic male sterility in maize, plant somatic cell genetics, and the population dynamics of genetic polymorphism. Physiologists, biologists, geneticists, and students will find a valuable reference material.
Author: National Research Council Publisher: National Academies Press ISBN: 0309165865 Category : Social Science Languages : en Pages : 184
Book Description
As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.
Author: Peter Berthold Publisher: Springer Science & Business Media ISBN: 3662059576 Category : Science Languages : en Pages : 601
Book Description
P. Berthold and E. Gwinnd Bird migration is an intriguing aspect of the living world - so much so that it has been investigated for as long, and as thoroughly, as almost any other natural phenomenon. Aristotle, who can count as the founder of scientific ornithology, paid very close attention to the migrations of the birds he ob served, but it was not until the reign of Friedrich II, in the first half of the 13th century, that reliable data began to be obtained. From then on, the data base grew rapidly. Systematic studies of bird migration were introduced when the Vogelwarte Rossitten was founded, as the first ornithological biological observation station in the world (see first chapter "In Memory of Vogelwarte Rossitten"). This area later received enormous impetus when ex perimental research on the subject was begun: the large-scale bird-ringing experiment initiated in Rossitten in 1903 by Johannes Thienemann (who was inspired by the pioneering studies of C. C. M. Mortensen), the experiments on photoperiodicity carried out by William Rowan in the 1920s in Canada and retention and release experiments performed by Thienemann in the 1930s in Rossitten, the first experimental study on the orientation of migratory birds. After the Second World War, migration research, while continuing in the previous areas, also expanded into new directions such as radar ornithology, ecophysiology and hormonal control mechanisms, studies of evolution, ge netics, telemetry and others.
Author: Gowher A. Wani Publisher: Cambridge Scholars Publishing ISBN: 1527554902 Category : Science Languages : en Pages : 139
Book Description
The invasion of ecosystems by alien species is a key driver of global environmental change and many invasive plant species attain sufficiently high abundance to alter the structure and function of an ecosystem. This book is the first publication to explain the reasons as to why some alien species undergo a profound shift in their ecological fortune from being minor components of their native ecosystems to becoming devastating dominants of non-native habitats. The book assesses the ecological, morphological, functional and genetic factors that contribute to invasion success. Cutting-edge tools in molecular genetics in the past two decades have opened up additional avenues for ecologists to address such questions and obtain novel insights in the ecology of invasive species. This text also highlights which molecular approaches are especially useful in discriminating between native and non-native populations of invaders that cannot otherwise be differentiated based on morphological traits. Such molecular approaches can yield useful insights with potential implications for biodiversity managers to identify alien invasive species that are likely to become invaders in the near future, thereby prioritizing them accordingly for different management strategies.
Author: National Research Council Publisher: National Academies Press ISBN: 0309166152 Category : Science Languages : en Pages : 254
Book Description
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Author: Esteban Domingo
Author: Christian R. Landry
Author: Esteban Domingo
Author: National Research Council
Author: 
Author: Institute of Medicine
Author: John G. Scandalios
Author: National Research Council
Author: Peter Berthold
Author: Gowher A. Wani
Author: National Research Council