Physiological Imaging with PET and SPECT in Dementia PDF Download

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 19

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Book Description
Dementia is a medical problem of increasingly obvious importance. The most common cause of dementia, Alzheimer's disease (AD) accounts for at least 50% of all cases of dementia, with multi-infarct dementia the next most common cause of the syndrome. While the accuracy of diagnosis of AD may range from 80 to 90%, there is currently no laboratory test to confirm the diagnosis. Functional imaging techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) offer diagnostic advantages since brain function is unequivocally disturbed in all dementing illnesses. Both PET and SPECT have been utilized in the study of dementia. While both techniques rely on principles of emission tomography to produce three dimensional maps of injected radiotracers, the differences between positron and single photon emission have important consequences for the practical applications of the two procedures. This briefly reviews the technical differences between PET and SPECT, and discusses how both techniques have been used in our laboratory to elucidate the pathophysiology of dementia. 32 refs., 2 figs.

Author: Ronald L. Van Heertum
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153392
Category : Medical
Languages : en
Pages : 474

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Book Description
This Fourth Edition reflects the significant recent progress that has occurred in functional brain imaging, particularly the increased use of PET/SPECT, the use of SPECT and PET in movement disorders and dementia, and advances in radiopharmaceutical development and instrumentation. Chapter topics include PET physics and instrumentation, PET radiopharmaceuticals, SPECT radiopharmaceuticals, and technical factors. The entire book has been thoroughly revised to reflect an appropriate balance between SPECT and PET applications. Highlights of this edition include a new chapter on neuroreceptor imaging and kinetic modeling, a new chapter on brain imaging in movement disorders, and significant updates on SPECT radiopharmaceuticals.

Author: Rudi A.J.O. Dierckx
Publisher: Springer
ISBN: 3642543073
Category : Medical
Languages : en
Pages : 1103

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Book Description
PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.

Author: Albert Gjedde
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 452

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Book Description
Physiological Imaging of the Brain with PET provides the latest techniques and applications for PET as a tool to study the physiology of the brain, and is sponsored by the International Society of Cerebral Blood Flow and Metabolism. It covers all of the fundamental disciplines of PET in one volume. Written by international experts in brain imaging, it is a useful reference for the active brain PET scientist, and a valuable introduction to students, clinicians, and researchers who wish to take advantage of the capabilities of this technique to study the normal and diseased brain. Key Features * Provides the latest techniques and applications of positron emission tomography (PET) * Covers all fundamental disciplines of PET in one volume * Serves as a comprehensive resource for students, clinicians and new researchers

Author: Rathan Subramaniam
Publisher: Elsevier Health Sciences
ISBN: 032322735X
Category : Medical
Languages : en
Pages : 110

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Book Description
Edited by leaders of the field, Rathan Subramaniam from Johns Hopkins and Jorge Barrio from UCLA, this issue of PET Clinics focuses on the evolving role of novel imaging techniques in negenerative and movement disorders common in the aged population.

Author: Frederik Barkhof
Publisher: Springer Science & Business Media
ISBN: 3642008186
Category : Medical
Languages : en
Pages : 295

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Book Description
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.

Author: Hojjat Ahmadzadehfar
Publisher: Springer Nature
ISBN: 3030658503
Category : Medical
Languages : en
Pages : 316

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Book Description
This book, now in a revised and updated second edition, covers the full spectrum of clinical applications of SPECT/CT in the diagnosis and therapy planning of benign and malignant diseases. All chapters have been thoroughly updated and some chapters have been completely rewritten by a new group of experts. The opening chapters discuss the technology and physics of SPECT/CT and its use in dosimetry. The role of SPECT/CT in the imaging of a range of pathologic conditions is then addressed in detail. Applications covered include imaging of the thyroid, neuroendocrine tumors, bone, cardiac scintigraphy, sentinel node scintigraphy and imaging of the lungs. Individual chapters are also devoted to therapy planning in selective internal radiation therapy of liver tumors and to Bremsstrahlung SPECT/CT. For Nuclear Medicine Physicians, Radiologists and medical students in this field, the book offers an essential and up-to-date source of information on this invaluable hybrid imaging technique.

Author: R. Duncan
Publisher: Springer Science & Business Media
ISBN: 9401153981
Category : Medical
Languages : en
Pages : 202

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Book Description
In the developed world, images of brain structure are available as an everyday diagnostic aid, and the characteristic appearances of most pathological conditions can be looked up in a textbook. Functional brain imaging is to this day less widely used, partly because most pressing diagnostic questions can be answered by refer ence to the patient's cerebral anatomy, partly for reasons of technical limitations of functional techniques. PET as a technique is sufficiently resource-demanding and complex to inhibit its use as an everyday diagnostic technique. SPECT lacked suitable tracers for many years, and early systems had poor spatial resolution. However, rotating gamma camera technology has advanced to the point where images of the brain of reasonable quality can be obtained at most large hospitals, and practical tracers, particularly of regional cerebral blood flow, are easily avail able. As research advances, clinical applications are emerging. A recent report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology! details a number of currently recognised clinical appli cations, some of which are dealt with in this book. Given this recognition, it is increasingly important that clinicians (particularly neuroclinicians, psychiatrists and specialists in cerebrovascular disease), nuclear medicine specialists and physicists acquire an idea of the major applications of the technique, and the research background on which these applications are based.

Author: David Linden
Publisher: Oxford University Press
ISBN: 0198739605
Category : Medical
Languages : en
Pages : 161

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Book Description
Neuroimaging and Neurophysiology in Psychiatry is an invaluable guide through the methods and applications of neuroimaging and neurophysiology.

Author: Eric Nofzinger
Publisher: Cambridge University Press
ISBN: 1107018633
Category : Medical
Languages : en
Pages : 445

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Book Description
An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.