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Author: A. R. Michell Publisher: Elsevier ISBN: 1483100820 Category : Nature Languages : en Pages : 389
Book Description
The Clinical Biology of Sodium: The Physiology and Pathophysiology of Sodium in Mammals presents a comparative view of mammalian sodium regulation and its clinical disturbances. This book covers a wide range of topics, including the physiological basis of fluid therapy, oral rehydration for diarrhea, the pathogenesis of edema, hypovolemia, endocrine regulation and disturbances, and nutritional requirement. Organized into 12 chapters, this book begins with an overview of the distribution and physiological functions of sodium. This text then explores the two processes that provide the basis of most of the non-endocrine functions of the kidneys, namely, glomerular filtration and tubular reabsorption of sodium. Other chapters consider the avoidable human and material costs of hypertension. This book discusses as well the molecular biology of sodium transport. The final chapter deals with the three mechanisms capable of detecting changes in cardiovascular filling. This book is a valuable resource for doctors, nurses, and veterinarians.
Author: A. R. Michell Publisher: Elsevier ISBN: 1483100820 Category : Nature Languages : en Pages : 389
Book Description
The Clinical Biology of Sodium: The Physiology and Pathophysiology of Sodium in Mammals presents a comparative view of mammalian sodium regulation and its clinical disturbances. This book covers a wide range of topics, including the physiological basis of fluid therapy, oral rehydration for diarrhea, the pathogenesis of edema, hypovolemia, endocrine regulation and disturbances, and nutritional requirement. Organized into 12 chapters, this book begins with an overview of the distribution and physiological functions of sodium. This text then explores the two processes that provide the basis of most of the non-endocrine functions of the kidneys, namely, glomerular filtration and tubular reabsorption of sodium. Other chapters consider the avoidable human and material costs of hypertension. This book discusses as well the molecular biology of sodium transport. The final chapter deals with the three mechanisms capable of detecting changes in cardiovascular filling. This book is a valuable resource for doctors, nurses, and veterinarians.
Author: M. Morad Publisher: Springer Science & Business Media ISBN: 9401139903 Category : Medical Languages : en Pages : 586
Book Description
Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.
Author: Erich E. Windhager Publisher: ISBN: 9780195060065 Category : Medical Languages : en Pages : 1210
Book Description
This new section of the Handbook of Physiology provides a comprehensive and authoritative account of current knowledge about kidney function. The early chapters emphasize structure, and relationships between structure and function. Tissue culture and renal micropuncture are among the many techniques discussed in detail. The physiology of non-renal tissues that serve as models of tubule function, comparative physiology, and developmental aspects of kidney function are similarly discussed. Glomerular filtration and mechanisms of transport of different solutes in water at the level of plasma membranes, of renal tubules, and of the whole kidney are covered in depth. The concentrating mechanism, the regulation of kidney function, including its relation to blood pressure homeostasis, and kidney-bone interactions are also reviewed in detail. Chapters on the biochemistry and metabolism of the kidney, diuretics, and erythropoietin round off the discussion. These two volumes offer the most up-to-date, comprehensive and authoritative coverage of kidney function available. Ninety international authorities present modern concepts of renal function, including the biochemistry, cell biology, and morphology of the kidney. Experimental techniques to study renal function are given detailed treatment. The chapters span the entire range of knowledge about kidney function, from the level of the plasma membrane to whole organ function, regulation and integration of kidney function into whole body homeostasis.
Author: Michel Félétou Publisher: Morgan & Claypool Publishers ISBN: 1615041230 Category : Science Languages : en Pages : 309
Book Description
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Author: N. Fabris Publisher: ISBN: Category : Family & Relationships Languages : en Pages : 394
Book Description
This volume is the result of the fourth international congress of the International Association of Biomedical Gerontology. It explores such subjects as the problems of biomarkers of ageing and longevity, ageing mechanisms at the cellular and molecular levels, and mechanisms of membrane ageing.
Author: H. A. Harfi Publisher: Springer Science & Business Media ISBN: 3642022022 Category : Medical Languages : en Pages : 4213
Book Description
The new edition of this classic reference offers a problem-based approach to pediatric diseases. It encompasses almost all pediatric subspecialties and covers every pediatric disease and organ system. It includes case studies and over 750 lavish illustrations.
Author: Jonas H. Ellenberg Publisher: CRC Press ISBN: 9780824788230 Category : Medical Languages : en Pages : 600
Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Author: Gisela H. Degen Publisher: Springer Science & Business Media ISBN: 3642794513 Category : Medical Languages : en Pages : 559
Book Description
The volume contains the main papers presented at the 1994 EUROTOX Congress, Basel, Switzerland, August 21-24, 1994. Toxicology has become a less descriptive science because more importance has been placed on the mechanisms underlying toxic effects. This is reflected in symposia and workshops devoted to species differences in organ toxicity, receptor-mediated toxicity and stereochemical effects of xenobiotics. Recent progress in the fields of immunotoxicology, ecotoxicology, and neurotoxicology is highlighted and documented together with the present discussion on harmonized regulatory guidelines.
Author: A. R. Michell
Author: A. R. Michell
Author: 
Author: M. Morad
Author: Erich E. Windhager
Author: 
Author: Michel Félétou
Author: N. Fabris
Author: H. A. Harfi
Author: Jonas H. Ellenberg
Author: Gisela H. Degen