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Author: William A. Glass Publisher: Springer Science & Business Media ISBN: 1468476270 Category : Science Languages : en Pages : 512
Book Description
The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.
Author: William A. Glass Publisher: Springer Science & Business Media ISBN: 1468476270 Category : Science Languages : en Pages : 512
Book Description
The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.
Author: Leroy Augenstein Publisher: Academic Press ISBN: 1483223272 Category : Science Languages : en Pages : 395
Book Description
Physical Processes in Radiation Biology covers the proceedings of an International Symposium on Physical Processes in Radiation Biology, held at the Kellogg Center for Continuing Education, Michigan State University on May 6-8, 1963, sponsored by the U.S. Atomic Energy Commission. The symposium aims to address the core problems of radiation biology concerning the absorption, distribution, and utilization of high energy packets in biological systems. This book is composed of 21 chapters, and begins with an introduction to the absorption, excitation, and transfer processes in molecular solids. The subsequent chapters discuss the nature of exciton processes; the mechanisms of charge transport in biological materials; the interactions of fast and slow electrons with model systems; the importance of liquid structures in determining the development of radiation damage; and the nature of the metastable species formed. The concluding chapters explore the importance of charge migration in energy transfer processes in different biological systems and the significance of higher excited levels in charge migration and energy transfer. These chapters also describe the nature of the hydration of electrons and protons in aqueous systems. This book will be of great value to radiation biologists, biophysicists, physical chemists, and physicists.
Author: Jürgen Kiefer Publisher: Springer Science & Business Media ISBN: 3642837697 Category : Science Languages : en Pages : 460
Book Description
The biological action of radiation undoubtedly constitutes an issue of actual con cern, particularly after incidences like those in Harrisburg or Chernobyl. These considerations, however, were not the reason for writing this book although it is hoped that it will also be helpful in this respect. The interaction of radiation with biological systems is such an interesting research objective that to my mind no special justification is needed to pursue these problems. The combination of physics, chemistry and biology presents on one hand a fascinating challenge to the student, on the other, it may lead to insights which are not possible if the dif ferent subjects remain clearly separated. Special problems of radiation biology have quite often led to new approaches in physics (or vice versa), a recent example is "microdosimetry" (chapter 4). Biological radiation a9tion comprises all levels of biological organization. It starts with the absorption in essential atoms and molecules and ends with the development of cancer and genetic hazards to future generations. The structure of the book reflects this. Beginning with physical and chemical fundamentals, it then turns to a description of chemical and subcellular systems. Cellular effects form a large part since they are the basis for understanding all further responses. Reactions of the whole organism, concentrating on mammals and especially humans, are subsequently treated. The book concludes with a short discussion of problems in radiation protection and the application of radiation in medical therapy. These last points are necessarily short and somewhat superficial.
Author: John T. Lett Publisher: Academic Press ISBN: 1483281892 Category : Science Languages : en Pages : 493
Book Description
Advances in Radiation Biology, Volume 9, provides an overview of the state of knowledge in radiation biology. The book contains nine chapters and begins with a study on the ways in which physical and chemical agents might trigger "regulatory dysfunction" and how these agents might interact with each other. This is followed by separate chapters on the mechanisms underlying changes in vascular function after doses of radiation in the therapeutic range and their role in the development of late effects in normal tissues; the future of hypoxic cell sensitizers in the clinical setting; DNA strand break formation by ionizing radiation; and major pathways which result in radiation-induced loss of cellular proliferative capacity. Subsequent chapters deal with the solid-state radiation chemistry of DNA; radiosensitivity of proliferating mammalian cells; the use of microwave/radiofrequency energy cancer treatment; and the decline of basic radiobiology.
Author: Hermann Dertinger Publisher: Springer Science & Business Media ISBN: 1468462474 Category : Science Languages : en Pages : 246
Book Description
There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.
Author: Leroy G. Augenstein Publisher: Academic Press ISBN: 1483282406 Category : Science Languages : en Pages : 382
Book Description
Advances in Radiation Biology, Volume 2, reflects a continuing effort to provide wide-ranging analyses of progress in various phases of radiation research. The articles cover a spectrum of topics varying from the initial physical events which allow us to discriminate color, to the chemical and biological processes which determine the extent and permanence of radiation damage, and finally to the role of genetic control and damage in determining the fate of irradiated cells. The basic emphasis of the articles also varies. In some, the main attempt is to review extensively the available data so as to evaluate the possible contributions of various mechanisms to a given phenomenon. One article is devoted an evaluation of one physical approach which appears to be a promising way of understanding color perception. These different treatments should be of value not only to the researcher but also to the student, inasmuch as each approach is invariably dictated by the state of the art in the area being covered.
Author: Leroy G. Augenstein Publisher: Academic Press ISBN: 1483282392 Category : Science Languages : en Pages : 297
Book Description
Advances in Radiation Biology, Volume 1, provides an overview of the state of knowledge in radiation biology. The book contains six chapters and opens with a review some of the recent work bearing on the nature of the radicals produced in water and on the rates of some of the reactions of the radicals. It also comments on some of the applications of the radical model which have been made. These are followed by a chapter on the process of photosynthesis, covering light absorption and emission by pigments, electromagnetic energy transfer among and between pigment molecules, and the (physical) transfer and migration of electronic charge. Subsequent chapters deal with the effects of tritium irradiation on cells; the effects of small doses of ionizing radiation; the radiation chemical reactions of the amino acids; and the nature of temperature effects on enzyme inactivation by various radiations.
Author: William A. Glass
Author: William A. Glass
Author: Raymond D. Cooper
Author: Leroy Augenstein
Author: Jürgen Kiefer
Author: John T. Lett
Author: Hermann Dertinger
Author: 
Author: Leroy G. Augenstein
Author: Leroy G. Augenstein
Author: National Research Council (U.S.). Subcommittee on Radiobiology