Pharmaceutical Formulations for Older Patients PDF Download

Author: Mine Orlu
Publisher: Springer Nature
ISBN: 3031358112
Category : Science
Languages : en
Pages : 294

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Book Description
Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.

Author: Sven Stegemann
Publisher: Springer
ISBN: 3319430998
Category : Medical
Languages : en
Pages : 764

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Book Description
This book aims to address the major aspects of future drug product development and therapy for older adults, giving practical guidance for the rational product and clinical development and prescribing of drug products to this ever growing segment of the population. With authors coming from key “aging” markets such as Europe, the USA, China and Japan, the book will provide valuable information for students, scientists, regulators, practitioners, and other healthcare professionals from academia, industry and regulatory bodies.

Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563435
Category : Medical
Languages : en
Pages : 65

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Book Description
Monitoring the safety of medicine use in children is of paramount importance since during the clinical development of medicines only limited data on this aspect are generated through clinical trials. Use of medicines outside the specifications described in the license (e.g. in terms of formulation indications contraindications or age) constitutes off-label and off-license use and these are a major area of concern. These guidelines are intended to improve awareness of medicine safety issues among everyone who has an interest in the safety of medicines in children and to provide guidance on effective systems for monitoring medicine safety in pediatric populations. This book will be of interest to all health care professionals medicine regulatory authorities pharmacovigilance centres academia the pharmaceutical industry and policy-makers. Systems for monitoring medicine safety are described in Annex 1. Pharmacovigilance methods and some examples of recent information on adverse reactions to marketed medicines are discussed in Annex 2.

Author: Rita K. Jew
Publisher:
ISBN: 9781585286515
Category : Children
Languages : en
Pages : 0

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Book Description
Now even more comprehensive, this fourth edition of Extemporaneous Formulations provides the same evidence-based formulation in easy-to-follow 'recipes' for 312 formulations, 129 of which are new.

Author: Susan Koch
Publisher: Springer Science & Business Media
ISBN: 160327457X
Category : Medical
Languages : en
Pages : 143

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Book Description
Medication use is the predominant form of health intervention in our society. And as we age, the likelihood of medication use increases dramatically, with more than 80 percent of those over age 65 using one or more medications. Along with that, the potential for medication errors also increases. Indeed adverse drug reactions (ADRs) and adverse drug events (ADEs) are a significant problem in older adults. Written in a practical format by contributors from Australia and the United States, Medication Management in Older Adults: A Concise Guide for Clinicians presents the available evidence on research interventions designed to reduce the incidence of medication errors in older adults, with a focus on acute, subacute, and residential (long-term) care settings. Because medication errors can occur at all stages in the medication process, from prescription by physicians to delivery of medication to the patient by nurses, and in any site in the health system, it is essential that interventions be targeted at all aspects of medication delivery. Chapters cover the principles of medical ethics in relation to medication management; common medication errors in the acute care sector; medication management in long-term care settings; nutrition and medications; the outcomes of a systematic review; dose form alterations; Electronic Health Records (EHR), Computerized Order Entry (COE), Beers criteria; and pharmacokinetics and pharmacodynamics. For those clinicians especially concerned with providing the best possible outcomes for their older adult patients, Medication Management in Older Adults: A Concise Guide for Clinicians is an invaluable resource and a significant contribution to the burgeoning literature on medication errors.

Author: Patricia Schofield, PhD, RGN
Publisher: John Wiley & Sons
ISBN: 9780470065488
Category : Medical
Languages : en
Pages : 226

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Book Description
This book will enable readers to understand the principles underpinning the management of pain which a particular emphasis upon the care of the older adult. The chapters will explore concepts that are recognised to be involved in the pain experience but each author will then add their own unique perspective by applying the principles to their specialist area of practice and the care of the older adult. It is structured to include the aims and outcomes of the chapter at the beginning so that readers can track their progress, and provides chapter outlines and further reading suggestions foir this unique topic area.

Author: Reza Shaker
Publisher: Springer Science & Business Media
ISBN: 1461437938
Category : Medical
Languages : en
Pages : 994

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Book Description
Principles of Deglutition is the first in class comprehensive multidisciplinary textbook to encompass the entire field of normal and disordered deglutition. It is designed as the definitive text for all those who desire to further their knowledge of the dynamic and expanding field of deglutology. The text is created to serve as a treasured reference for clinicians, educators and trainees from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and others. Principles of Deglutition brings together the state-of-knowledge from 12 disciplines involved in dysphagia through contributions of over one hundred thought leaders and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge that exists in each of the contributing disciplines into one comprehensive information platform. Principles of Deglutition provides a one-stop destination for members of all specialties to obtain state-of-the-art and critically reviewed information regarding deglutition physiology, pathophysiology, diagnosis and management. It delivers a comprehensive and in depth review of deglutition related cerebral cortical, brainstem, peripheral nerves, and neuromuscular mechanisms, advanced diagnostic modalities and standard of care and cutting edge medical, rehabilitative and surgical treatments. It is an essential reference for all deglutologists.

Author: Geoffrey D Tovey
Publisher: Royal Society of Chemistry
ISBN: 1839165618
Category : Science
Languages : en
Pages : 359

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Book Description
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Following on from Pharmaceutical Formulation, which covered traditional dosage forms such as tablets and capsules, this volume expands upon those formulations to cover a more diverse range of less common dosage forms. Novel routes of administration are covered from inhalational, dermal and transdermal formulations to ocular, oral suspensions, vaccines and nanoparticle drug delivery. The methods through which these formulations are processed and manufactured is also covered, providing essential knowledge to ensure quality, efficiency, and acceptable costing. Specialised Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry and will equip readers with the ability to effectively and reliably produce products which can be approved, manufactured and made available to administer to patients.

Author: Mitchell J. Stoklosa
Publisher:
ISBN: 9780812110074
Category : Medical
Languages : en
Pages : 428

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Book Description

Author: Martin Duerden
Publisher:
ISBN: 9781909029187
Category : Chemotherapy
Languages : en
Pages : 56

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Book Description
This report provides a definition of polypharmacy, considers the evidence around medicines management and concludes that there is a need for guidelines on the treatment of multi-morbidity and that clinicians need to work alongside patients to empower them to make informed decisions about their medication.