Author: Beate Rau
Publisher: Springer Nature
ISBN: 3030626407
Category : Medical
Languages : en
Pages : 407
Book Description
This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.
Peritoneal Tumors and Metastases
Author: Beate Rau
Publisher: Springer Nature
ISBN: 3030626407
Category : Medical
Languages : en
Pages : 407
Book Description
This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.
Publisher: Springer Nature
ISBN: 3030626407
Category : Medical
Languages : en
Pages : 407
Book Description
This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.
Management of Peritoneal Metastases- Cytoreductive Surgery, HIPEC and Beyond
Author: Aditi Bhatt
Publisher: Springer
ISBN: 9811070539
Category : Medical
Languages : en
Pages : 577
Book Description
The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.
Publisher: Springer
ISBN: 9811070539
Category : Medical
Languages : en
Pages : 577
Book Description
The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.
Peritoneal Carcinomatosis: Principles of Management
Author: Paul H. Sugarbaker
Publisher: Springer Science & Business Media
ISBN: 1461312477
Category : Medical
Languages : en
Pages : 434
Book Description
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.
Publisher: Springer Science & Business Media
ISBN: 1461312477
Category : Medical
Languages : en
Pages : 434
Book Description
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.
Treatment of Peritoneal Surface Malignancies
Author: Angelo Di Giorgio
Publisher: Springer
ISBN: 8847057116
Category : Medical
Languages : en
Pages : 398
Book Description
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.
Publisher: Springer
ISBN: 8847057116
Category : Medical
Languages : en
Pages : 398
Book Description
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.
Peritoneal Surface Malignancies
Author: Emel Canbay
Publisher: Springer
ISBN: 3319129376
Category : Medical
Languages : en
Pages : 127
Book Description
This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.
Publisher: Springer
ISBN: 3319129376
Category : Medical
Languages : en
Pages : 127
Book Description
This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.
Pathology of Peritoneal Metastases
Author: Olivier Glehen
Publisher: Springer Nature
ISBN: 9811537739
Category : Medical
Languages : en
Pages : 281
Book Description
This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors.
Publisher: Springer Nature
ISBN: 9811537739
Category : Medical
Languages : en
Pages : 281
Book Description
This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors.
Perioperative Chemotherapy
Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Diagnostic Imaging: Gastrointestinal E-Book
Author: Siva P. Raman
Publisher: Elsevier Health Sciences
ISBN: 032340040X
Category : Medical
Languages : en
Pages : 1149
Book Description
Ideal for trainees and practicing radiologists, Diagnostic Imaging: Gastrointestinal, 3rd Edition provides comprehensive coverage of every important topic in abdominal and gastrointestinal imaging. Featuring an increased number of illustrations, graphics, and multimodality imaging, this updated medical reference book will aid you in recognizing the characteristic and variant appearances of both common and uncommon abdominal disorders. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Expanded coverage of the most important topics and trends in fluoroscopic evaluation of the GI tract, including evaluation of patients before and after bariatric surgery, fundoplication, and surgery for esophageal carcinoma. Updated sections covering disorders of the liver, biliary tract, and pancreas with information and images regarding new classification and treatment implications for pancreatitis, including autoimmune (IgG4-related) pancreatitis. Increased number of illustrations of all appropriate imaging modalities, such as multiplanar CT, sonography, MR, and PET/CT. Offers information on all forms of acute and chronic hepatitis and cirrhosis, as well as critical knowledge regarding imaging techniques that allow radiologists to distinguish among focal lesions in the cirrhotic liver. Essential information is distilled into a succinct, bulleted format with numerous high-quality images and "Key Facts" boxes to facilitate learning.
Publisher: Elsevier Health Sciences
ISBN: 032340040X
Category : Medical
Languages : en
Pages : 1149
Book Description
Ideal for trainees and practicing radiologists, Diagnostic Imaging: Gastrointestinal, 3rd Edition provides comprehensive coverage of every important topic in abdominal and gastrointestinal imaging. Featuring an increased number of illustrations, graphics, and multimodality imaging, this updated medical reference book will aid you in recognizing the characteristic and variant appearances of both common and uncommon abdominal disorders. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Expanded coverage of the most important topics and trends in fluoroscopic evaluation of the GI tract, including evaluation of patients before and after bariatric surgery, fundoplication, and surgery for esophageal carcinoma. Updated sections covering disorders of the liver, biliary tract, and pancreas with information and images regarding new classification and treatment implications for pancreatitis, including autoimmune (IgG4-related) pancreatitis. Increased number of illustrations of all appropriate imaging modalities, such as multiplanar CT, sonography, MR, and PET/CT. Offers information on all forms of acute and chronic hepatitis and cirrhosis, as well as critical knowledge regarding imaging techniques that allow radiologists to distinguish among focal lesions in the cirrhotic liver. Essential information is distilled into a succinct, bulleted format with numerous high-quality images and "Key Facts" boxes to facilitate learning.
Surgical Management of Advanced Pelvic Cancer
Author: Desmond C. Winter
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Fundamentals of Oncologic PET/CT E-Book
Author: Gary A. Ulaner
Publisher: Elsevier Health Sciences
ISBN: 032356867X
Category : Medical
Languages : en
Pages : 291
Book Description
In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years' worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion. - Based on the Annual Oncologic PET/CT Continuing Education Course founded and directed by Dr. Ulaner. - Provides step-by-step guidance on how to interpret PET/CT images for patients with cancer. - Uses a unique, highly practical format, presenting common and uncommon findings for each organ system, and then explaining how to best arrive at a diagnosis for those findings. - Describes how to integrate PET findings with CT, MR, ultrasound, and radiography, to increase specificity of PET findings. - Features more than 1,000 high-quality PET, CT, and correlative radiographic images, with over 600 in full color. - Discusses how to avoid common interpretive pitfalls. - Demonstrates how to organize an FDG PET/CT report efficiently and concisely. - Includes a separate chapter on novel radiotracers – including Sodium Fluoride, DOTATATE, Choline, Fluciclovine, and PSMA targeting agents. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Publisher: Elsevier Health Sciences
ISBN: 032356867X
Category : Medical
Languages : en
Pages : 291
Book Description
In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years' worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion. - Based on the Annual Oncologic PET/CT Continuing Education Course founded and directed by Dr. Ulaner. - Provides step-by-step guidance on how to interpret PET/CT images for patients with cancer. - Uses a unique, highly practical format, presenting common and uncommon findings for each organ system, and then explaining how to best arrive at a diagnosis for those findings. - Describes how to integrate PET findings with CT, MR, ultrasound, and radiography, to increase specificity of PET findings. - Features more than 1,000 high-quality PET, CT, and correlative radiographic images, with over 600 in full color. - Discusses how to avoid common interpretive pitfalls. - Demonstrates how to organize an FDG PET/CT report efficiently and concisely. - Includes a separate chapter on novel radiotracers – including Sodium Fluoride, DOTATATE, Choline, Fluciclovine, and PSMA targeting agents. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.