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Author: Amitava Biswas Publisher: ISBN: Category : Languages : en Pages : 476
Book Description
Although Parkinson's disease (PD) is historically seen as a hypokinetic disorder of movements, including speech, recent studies have suggested degradation of sensorimotor integration in PD. Therefore, this study addresses the following questions. (1) Is there any sensory deficit in PD that correlates to the speech deficit? (2) Do PD patients significantly differ from healthy individuals on this account? A total of 36 participants included 12 PD patients, 12 age matched geriatric healthy subjects (GN), and 12 young healthy subjects (YN) in the age group of 20--30 years. All participants had normal cognitive function and normal hearing. Sensory evaluations included Tests of Basic Auditory Capability (TBAC), and tests of labial mechanosensation by Johnson-VanBoven-Phillips probes (JVP). Speech performance was evaluated by a new analytic measure: Guesstimate of Articulatory Performance (GAP) that extracts an overall score of formant transition from the acoustic signal, and by two conventional perceptual measures: Assessment of Intelligibility of Dysarthric Speech (AIDS), and Communication Efficiency Ratio (CER). Compared to the GN group, The PD group showed significant deficits in mechanosensation and speech performance but not in auditory performance. Compared to the YN group, the GN group showed significant deficits in mechanosensation and auditory performance but not in speech performance. Only the PD group showed a significant correlation between speech performance and mechanosensation. The results suggest that motor speech deficits may not be normally associated with mechanosensory deficits, but the association may be significant in PD. A computational model was investigated for theoretical interpretation of the results. This model was based on the Kalman principle of sensorimotor integration. Selective lesioning of the model also indicate that simultaneous degradation of sensorimotor integration and mechanosensation may be intrinsic in hypokinetic dysarthria.
Author: Amitava Biswas Publisher: ISBN: Category : Languages : en Pages : 476
Book Description
Although Parkinson's disease (PD) is historically seen as a hypokinetic disorder of movements, including speech, recent studies have suggested degradation of sensorimotor integration in PD. Therefore, this study addresses the following questions. (1) Is there any sensory deficit in PD that correlates to the speech deficit? (2) Do PD patients significantly differ from healthy individuals on this account? A total of 36 participants included 12 PD patients, 12 age matched geriatric healthy subjects (GN), and 12 young healthy subjects (YN) in the age group of 20--30 years. All participants had normal cognitive function and normal hearing. Sensory evaluations included Tests of Basic Auditory Capability (TBAC), and tests of labial mechanosensation by Johnson-VanBoven-Phillips probes (JVP). Speech performance was evaluated by a new analytic measure: Guesstimate of Articulatory Performance (GAP) that extracts an overall score of formant transition from the acoustic signal, and by two conventional perceptual measures: Assessment of Intelligibility of Dysarthric Speech (AIDS), and Communication Efficiency Ratio (CER). Compared to the GN group, The PD group showed significant deficits in mechanosensation and speech performance but not in auditory performance. Compared to the YN group, the GN group showed significant deficits in mechanosensation and auditory performance but not in speech performance. Only the PD group showed a significant correlation between speech performance and mechanosensation. The results suggest that motor speech deficits may not be normally associated with mechanosensory deficits, but the association may be significant in PD. A computational model was investigated for theoretical interpretation of the results. This model was based on the Kalman principle of sensorimotor integration. Selective lesioning of the model also indicate that simultaneous degradation of sensorimotor integration and mechanosensation may be intrinsic in hypokinetic dysarthria.
Author: Joseph Jankovic Publisher: Lippincott Williams & Wilkins ISBN: 9780781778817 Category : Medical Languages : en Pages : 748
Book Description
Written by an international group of renowned experts, the Fifth Edition of this premier reference provides comprehensive, current information on the genetics, pathophysiology, diagnosis, medical and surgical treatment, and behavioral and psychologic concomitants of all common and uncommon movement disorders. Coverage includes Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. This edition features extensive updates on genetics, imaging, and therapeutics of Parkinson's disease, other parkinsonian disorders, and all hyperkinetic movement disorders. A bound-in CD-ROM, Video Atlas of Movement Disorders, demonstrates the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.
Author: Reinhard Dengler Publisher: IOS Press ISBN: 9781586030810 Category : Medical Languages : en Pages : 240
Book Description
Despite the intensive experimental and theoretical studies for over a century, the general processes involved in neural control of pasture and movement, in learning of motor behaviour in healthy subjects and in adaptation in pathology were and remain a challenging problems for the scientists in the field of sensorimotor control. The book is the outcome of the Advanced Research Workshop Sensorimotor Control, where the focus was on the state and the perspectives of the study in the field.
Author: Gerhard Blanken Publisher: Walter de Gruyter ISBN: 3110203375 Category : Language Arts & Disciplines Languages : en Pages : 978
Book Description
This handbook is geared towards the following aims: Reviewing the state of research on disordered language perception and production in adults and children. Describing and discussing present attempts at modelling human language processing by using linguistic disorders and pathologies as a data base. Presenting diagnostic and therapeutic concepts. Pointing out gaps and inconcistencies in current knowledge and theories. In bringing together knowlegde of different sources and disciplines under a common roof, the editors have achieved a comprehensive overview of the state of the art in the field of language pathology. Because of the diversity of the disciplines contributing to this scientific field, the chapters differ clearly in theories and methodologies. Yet this handbook represents a clear and common interdisciplinary contribution to linguistic disorders and pathologies and, furthermore, demonstrates the amount of interdisciplinary interaction still required. We chose this title in order to encompass as broadly as possible abnormalities and alterations of language perception, comprehension and production in adults and children, including nonpathological disorders. This handbook will be of interest to anybody involved with disordered language and/or language and speech disturbances, such as linguists and psychologists working in related research areas or teaching related subjects, scientists analyzing and modelling linguistic and cognitive processes (e.g. in Cognitive Psychology, Psycholinguistics, Neurolinguistics, Neuropsychology, Behavioural Neurology, Artificial Intelligence Research, and Cognitive Science), clinicians dealing with aquired or developmental language disorders, and speech pathologists and therapists. Besides presenting the state of the art, the handbook provides rich bibliographical information for research workers, clinicians, and advanced students.
Author: Kapil D. Sethi Publisher: Springer Nature ISBN: 3030537218 Category : Medical Languages : en Pages : 145
Book Description
This book addresses the challenges in the differential diagnosis and management of paroxysmal movement disorders. It provides the latest information on the genetics and pathophysiology, neurophysiology and neuroimaging of the core group of disorders in the field, namely the paroxysmal dyskinesias (PxD). Focused and concise, this guide features chapters that discuss other conditions that may be paroxysmal such as, episodic ataxia, startle syndromes and other more complicated groups of paroxysmal movement disorders such as ATP1A3 spectrum disorders. A chapter on secondary (acquired) paroxysmal dyskinesia highlights medical and other disorders that may result in paroxysmal dyskinesia. The book features a particularly nuanced chapter that discusses recent discoveries in the genetic aspects of PxD, relaying that paroxysmal dyskinesias are not channelpathies, but in fact are synaptophies and transportopathies. Additionally, expertly written chapters are supplemented by high quality images, tables, and videos. Paroxysmal Movement Disorders: A Practical Guide is primarily written to educate the reader on how to make a syndromic diagnosis of paroxysmal movement disorders and how to build the diagnostic work-up accordingly, as well as how to manage patients with paroxysmal movement disorders.
Author: David P. Kuehn Publisher: Little, Brown Medical Division ISBN: Category : Language Arts & Disciplines Languages : en Pages : 344
Book Description
Tiring of being a studious girl when nobody sees anything about her beyond her weight, Leah calls an older man, pretending to be her thin, popular friend, only to find her life spinning out of control as she discovers herself and her true friends.
Author: Louis R. Caplan Publisher: Cambridge University Press ISBN: 1107018862 Category : Medical Languages : en Pages : 633
Book Description
A comprehensive survey of dysfunction due to stroke, this revised edition remains the definitive guide to stroke patterns and syndromes.
Author: Amitava Biswas
Author: Amitava Biswas
Author: Joseph Jankovic
Author: 
Author: Reinhard Dengler
Author: Gerhard Blanken
Author: Kapil D. Sethi
Author: Society for Neuroscience. Meeting
Author: David P. Kuehn
Author: D. G. Cunningham Owens
Author: Louis R. Caplan