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Peptide Science — Present and Future

Peptide Science — Present and Future PDF Author: Yasutsugu Shimonishi
Publisher: Springer Science & Business Media
ISBN: 0306468646
Category : Science
Languages : en
Pages : 887

Book Description
In the late 1980s, Peptide Societies were established in Europe, the United States, and Japan, and more recently, in the Asian and the Pacific Rim regions including Australia, China, and Korea. At the time of the establishment of the American, European and Japanese Peptide Societies, the International Liaison Organizing Committee representing these Peptide Societies, along with the Australian Peptide Society, began discussions for holding international confer ences which would supercede or be held in lieu of the numerous individual meetings, held by the peptide societies of each individual country or region. The representative of the Chinese Peptide Society participated in these discus sion in the International Liaison Organizing Committee at the meeting of the American Peptide Symposium in Nashville, in June 1997. After lengthy discus sions over several years, we agreed to organize and host the International Peptide Symposium in Japan. The First International Peptide Symposium (IPS’97) was held on November 30–December 5, 1997, in Kyoto, and was co sponsored by four Peptide Societies. The attendance at this Symposium was 550 participants, including representatives from 32 different countries. We were very pleased with this outcome and anticipate an even larger attendance for forthcoming Symposia in future years. The revolution and advances in science and technology during the past two decades has caused traditional peptide chemistry to expand to peptide science, spreading from physical science to biology, pharmacology, and medicine.

Peptide Science — Present and Future

Peptide Science — Present and Future PDF Author: Yasutsugu Shimonishi
Publisher: Springer Science & Business Media
ISBN: 0306468646
Category : Science
Languages : en
Pages : 887

Book Description
In the late 1980s, Peptide Societies were established in Europe, the United States, and Japan, and more recently, in the Asian and the Pacific Rim regions including Australia, China, and Korea. At the time of the establishment of the American, European and Japanese Peptide Societies, the International Liaison Organizing Committee representing these Peptide Societies, along with the Australian Peptide Society, began discussions for holding international confer ences which would supercede or be held in lieu of the numerous individual meetings, held by the peptide societies of each individual country or region. The representative of the Chinese Peptide Society participated in these discus sion in the International Liaison Organizing Committee at the meeting of the American Peptide Symposium in Nashville, in June 1997. After lengthy discus sions over several years, we agreed to organize and host the International Peptide Symposium in Japan. The First International Peptide Symposium (IPS’97) was held on November 30–December 5, 1997, in Kyoto, and was co sponsored by four Peptide Societies. The attendance at this Symposium was 550 participants, including representatives from 32 different countries. We were very pleased with this outcome and anticipate an even larger attendance for forthcoming Symposia in future years. The revolution and advances in science and technology during the past two decades has caused traditional peptide chemistry to expand to peptide science, spreading from physical science to biology, pharmacology, and medicine.

De Novo Peptide Design

De Novo Peptide Design PDF Author: Vibin Ramakrishnan
Publisher: Academic Press
ISBN: 0323985432
Category : Science
Languages : en
Pages : 297

Book Description
De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents. - Gives comprehensive coverage, including peptide design, modeling, synthesis and applications - Presents emerging topics in the design of peptide-based therapeutics - Details the latest developments in the fields of therapeutic peptides and bio-nanotechnology - Considers peptide design and the tailoring of peptides to specific functions - Offers computational tools and algorithms for peptide design and experimental protocols for peptide chemistry

Amino Acids, Peptides and Proteins

Amino Acids, Peptides and Proteins PDF Author: J S Davies
Publisher: Royal Society of Chemistry
ISBN: 1847552757
Category : Science
Languages : en
Pages : 416

Book Description
In an ever-increasing domain of activity Amino Acids Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 30 provides a review of literature published during 1997. Comprising a comprehensive review of significant developments at this biology/chemistry interface each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters ranging from current trends in their synthesis and conformational and structural analysis to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries and at the biology/chemistry interface in academia will find this an indispensable reference source.

Peptides: The Wave of the Future

Peptides: The Wave of the Future PDF Author: Richard A. Houghten
Publisher: Springer
ISBN: 9401004641
Category : Science
Languages : en
Pages : 1171

Book Description
This volume contains the proceedings of the Second International Peptide Symposium and the Seventeenth American Peptide Symposium, held on 9-14 June, 2001, at the Town and Country Resort in San Diego, California. The biennial meeting was held under the auspices of the American Peptide Society. In addition to the main Symposium, we were honored to have the Merrifield Satellite Symposium, honoring Bruce Merrifield's accomplishments on his 80th birthday. Over 1250 participants from around the world attended the lectures, posters, and exhibits. Reflecting the international nature of the Symposium, there were participants from 37 countries in attendance. In addition to the 75 plenary lectures, there were over 575 poster presentations, and 70 commercial exhibits as well as booths from the American, Australian, Chinese, European, and Japanese Peptide Societies. These proceedings include plenary lectures and oral and poster presentations collected from a wide diversity of topics providing a truly comprehensive and up-to-date overview of the field of peptide science. This publication contains essential reference information for researchers active in peptide science.

Carnosine and Oxidative Stress in Cells and Tissues

Carnosine and Oxidative Stress in Cells and Tissues PDF Author: Alexander A. Boldyrev
Publisher: Nova Publishers
ISBN: 9781600214110
Category : Medical
Languages : en
Pages : 312

Book Description
The main aim of this new book is to summarise the knowledge on the metabolic transformation of carnosine in excitable tissues of animals and human beings and to analyse the nature of its biological activity. At the beginning of monograph, the short history of the problem is stated. Distribution of carnosine in tissues, its appearance in ontogeny of vertebrates and correlation between carnosine content and functional activity of tissues are discussed. Chemical properties of carnosine and its natural derivatives and their ability to bind heavy metals and protons in water solution are documented. Special attention is paid to free radical quenching ability and to anti-glycating action. Biological activity of carnosine and carnosine containing compounds was tested using biological models of several levels of complexity, starting from individual enzymes and acellular mixtures and finishing to living cells and survival animals. Effects of carnosine on the whole animals under ischemic, hypoxic and other extreme conditions are described. In conclusion, the ability of carnosine to protect brain and muscular tissues from oxidative injury during exhausting exercise, extreme loading or neurodegenerative diseases is demonstrated. Based on these properties, carnosine is postulated to be a potent protector of human beings from oxidative stress.

Amino Acids, Peptides and Proteins

Amino Acids, Peptides and Proteins PDF Author: Maxim Ryadnov
Publisher: Royal Society of Chemistry
ISBN: 1782622683
Category : Science
Languages : en
Pages : 259

Book Description
Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology/chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas for example new bioconjugates of metal complexes with peptides and derivatization of peptides for improved detection by mass spectrometry. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference to developments now and looking to the future.

Advances in Invertebrate (Neuro)Endocrinology (2-volume set)

Advances in Invertebrate (Neuro)Endocrinology (2-volume set) PDF Author: Saber Saleuddin
Publisher: CRC Press
ISBN: 0429555008
Category : Nature
Languages : en
Pages : 875

Book Description
Advances in Invertebrate (Neuro)Endocrinology: A Collection of Reviews in the Post-Genomic Era (2-volume set) provides an informative series of reviews from expert scientists who are at the forefront of their research into the endocrinology of invertebrates. These two volumes are timely and appropriate in this post-genomic era because of the rapid pace of change brought about by genome projects, functional genomics, and genetics (omics technologies). The volume shows the rich history and strong tradition of cutting-edge research using invertebrates that has opened up our broader understanding of comparative endocrinology and the evolution of regulatory pathways and systems. These reviews set the scene and context for this exciting new era of understanding that has come from this post-genomic revolution. This book undertakes the daunting task of covering most of the diverse endocrine systems that exist among invertebrates. The papers in this book will advance our knowledge of invertebrate endocrinology but also of endocrinology in general, making the book will be valuable to researchers and students.

RAS: Past, Present, and Future

RAS: Past, Present, and Future PDF Author:
Publisher: Academic Press
ISBN: 0128244860
Category : Science
Languages : en
Pages : 358

Book Description
Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once "undruggable RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers. - Overview of the history and development of efforts to pharmacologically inhibit RAS. - Discussion of the biochemistry and biology of different RAS mutant proteins and how this might be effectively leveraged in the development of anti-RAS therapies. - Up-to-date reviews of the cutting-edge approaches to develop new anti-RAS pharmacologics.

Current and Future Aspects of Nanomedicine

Current and Future Aspects of Nanomedicine PDF Author: Islam Khalil
Publisher: BoD – Books on Demand
ISBN: 1789858690
Category : Technology & Engineering
Languages : en
Pages : 144

Book Description
Nanomedicine refers to the use of nanotechnological applications in biomedical fields such as therapeutics, diagnostics, monitoring, visualization, tissue engineering and even surgery. This book presents recent updates in the nanomedicine market and discusses several aspects of drug delivery and tissue regeneration using different platforms and devices.

Advances in Invertebrate (Neuro)Endocrinology

Advances in Invertebrate (Neuro)Endocrinology PDF Author: Saber Saleuddin
Publisher: CRC Press
ISBN: 1000047474
Category : Nature
Languages : en
Pages : 466

Book Description
Advances in Invertebrate (Neuro)Endocrinology: A Collection of Reviews in the Post-Genomic Era (2-volume set) provides an informative series of reviews from expert scientists who are at the forefront of their research into the endocrinology of invertebrates. These two volumes are timely and appropriate in this post-genomic era because of the rapid pace of change brought about by genome projects, functional genomics, and genetics (omics technologies). The volume shows the rich history and strong tradition of cutting-edge research using invertebrates that has opened up our broader understanding of comparative endocrinology and the evolution of regulatory pathways and systems. These reviews set the scene and context for this exciting new era of understanding that has come from this post-genomic revolution. This book undertakes the daunting task of covering most of the diverse endocrine systems that exist among invertebrates. The papers in this book will advance our knowledge of invertebrate endocrinology but also of endocrinology in general, making the book will be valuable to researchers and students.