Vertebrate Limb and Somite Morphogenesis PDF Download

Author: British Society for Developmental Biology
Publisher:
ISBN:
Category : Chickens
Languages : en
Pages : 498

View

Book Description

Author: Spyros Papageorgiou
Publisher: Springer Science & Business Media
ISBN: 0387689907
Category : Medical
Languages : en
Pages : 158

View

Book Description
Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.

Author: J. R. Hinchliffe
Publisher: Oxford University Press, USA
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 306

View

Book Description

Author: Philip K. Maini
Publisher: Springer Science & Business Media
ISBN: 1461301335
Category : Mathematics
Languages : en
Pages : 327

View

Book Description
This 121st IMA volume, entitled MATHEMATICAL MODELS FOR BIOLOGICAL PATTERN FORMATION is the first of a new series called FRONTIERS IN APPLICATION OF MATHEMATICS. The FRONTIERS volumes are motivated by IMA pro grams and workshops, but are specially planned and written to provide an entree to and assessment of exciting new areas for the application of mathematical tools and analysis. The emphasis in FRONTIERS volumes is on surveys, exposition and outlook, to attract more mathematicians and other scientists to the study of these areas and to focus efforts on the most important issues, rather than papers on the most recent research results aimed at an audience of specialists. The present volume of peer-reviewed papers grew out of the 1998-99 IMA program on "Mathematics in Biology," in particular the Fall 1998 em phasis on "Theoretical Problems in Developmental Biology and Immunol ogy." During that period there were two workshops on Pattern Formation and Morphogenesis, organized by Professors Murray, Maini and Othmer. James Murray was one of the principal organizers for the entire year pro gram. I am very grateful to James Murray for providing an introduction, and to Philip Maini and Hans Othmer for their excellent work in planning and preparing this first FRONTIERS volume. I also take this opportunity to thank the National Science Foundation, whose financial support of the IMA made the Mathematics in Biology pro gram possible.

Author: Raul Fleischmajer (ed)
Publisher:
ISBN:
Category : Epithelium
Languages : en
Pages : 348

View

Book Description

Author: Ruth Bellairs
Publisher: Springer Science & Business Media
ISBN: 1489920137
Category : Science
Languages : en
Pages : 318

View

Book Description
Somite development is a unique and important topic; unique because somitic mesoderm is the first tissue to become segmented, important because the somites - once established - exert a profound influence on other seg mental structures which form later. Somite development is of interest at a number of levels. In one aspect, demarcation of a specific number of somites and size regulation, it is a particularly intriguing example of embryonic pattern formation, 'especially in vew of its possible relation to homoeobox-controlled segmentation in insects. At another level, somite development has long been studied by compara tive anatomists, but only recently has new light been thrown on such sub jects as segmentation of the head, proposed in the 18th century by Goethe and now a live issue for developmental biologists. Somit es are simple when they first appear, but very complex structures arise from them. These include the vertebrae and the axial and other muscles and consequently there is a wealth of morphogenetic problems to be explored. Sometimes their morphogenesis is disturbed, by genetic or environ mental factors, and there are many clinical conditions which arise as a result.

Author: J.Richard Hinchliffe
Publisher: Springer Science & Business Media
ISBN: 1461533104
Category : Science
Languages : en
Pages : 434

View

Book Description
Following pioneering work by Harrison on amphibian limbs in the 1920s and by Saunders (1948) on the apical ridge in chick limbs, limb development became a classical model system for investigating such fundamental developmental issues as tissue interactions and induction, and the control of pattern formation. Earlier international conferences, at Grenoble 1972, Glasgow 1976,and Storrs, Connecticut 1982, reflected the interests and technology of their time. Grenoble was concerned with ectoderm-mesenchyme interaction, but by the time of the Glasgow meeting, the zone of polarizing activity (ZPA) and its role in control of patterning was the dominant theme. Storrs produced the first intimations that the ZPA could be mimicked by retinoic acid (RA), but the diversity of extracellular masrix ~olecules,particularly in skeletogenesis,was the main focus of attention. By 1990, the paradigms had again shifted. Originally, the planners of the ARW saw retinoic acid (as a possible morphogen controlling skeletal patterning), the variety of extracellular matrix components and their roles, and the developmental basis of limb evolution as the leading contemporary topics. However, as planning proceeded, it was clear that the new results emerging from the use of homeobox gene probes (first developed to investigate the genetic control of patterning of Drosophila embryos) to analyse the localised expression of "patterning genes" in limb buds would also be an important theme.

Author: Dennis Bray
Publisher: Garland Science
ISBN: 9780815332824
Category : Cells
Languages : en
Pages : 396

View

Book Description
This book vividly describes how complex and integrated movements can arise from the properties and behaviors of biological molecules. It provides a uniquely integrated account in which the latest findings from biophysics and molecular biology are put into the context of living cells. This second edition is updated throughout with recent advances in the field and has a completely revised and redrawn art program. The text is suitable for advanced undergraduates, graduate students, and for professionals wishing for an overview of this field.

Author: S. Barry Cooper
Publisher: Cambridge University Press
ISBN: 131658917X
Category : Mathematics
Languages : en
Pages : 398

View

Book Description
Alan Turing (1912–1954) made seminal contributions to mathematical logic, computation, computer science, artificial intelligence, cryptography and theoretical biology. In this volume, outstanding scientific thinkers take a fresh look at the great range of Turing's contributions, on how the subjects have developed since his time, and how they might develop still further. The contributors include Martin Davis, J. M. E. Hyland, Andrew R. Booker, Ueli Maurer, Kanti V. Mardia, S. Barry Cooper, Stephen Wolfram, Christof Teuscher, Douglas Richard Hofstadter, Philip K. Maini, Thomas E. Woolley, Eamonn A. Gaffney, Ruth E. Baker, Richard Gordon, Stuart Kauffman, Scott Aaronson, Solomon Feferman, P. D. Welch and Roger Penrose. These specially commissioned essays will provoke and engross the reader who wishes to understand better the lasting significance of one of the twentieth century's deepest thinkers.

Author: Brian K. Hall
Publisher: Academic Press
ISBN: 0124166857
Category : Science
Languages : en
Pages : 911

View

Book Description
Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. - Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations - Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning - Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages - Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) - Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data - Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche