Pathophysiological mechanisms of disorders of consciousness: From the perspective of the abnormal neural oscillations PDF Download

Author: Qiuyou Xie
Publisher: Frontiers Media SA
ISBN: 2832543650
Category : Science
Languages : en
Pages : 140

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Author: Carl Faingold
Publisher: Academic Press
ISBN: 0124158641
Category : Medical
Languages : en
Pages : 537

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Book Description
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Author: Stanislav Tregub
Publisher: STANISLAV TREGUB
ISBN: 5604473987
Category : Psychology
Languages : en
Pages : 180

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Book Description
In psychotherapy and psychiatry, mental illness diagnostics is limited to the description of symptoms and has nothing to do with assessing the state of the organ that performs the mental functions. In other branches of medicine, any diagnosis aims to answer the question about the physical disturbance of the internal technology of the body. But the Mind remains outside of this correct approach. As a result, all systemic mental pathologies are currently incurable. This absurd situation is due to the lack of a physically grounded theoretical model of the Mind. Without it, practical treatment of the disorders remains ‘wandering in the dark.’ How can we fix something if there is no understanding of what it is and how it works? Within the Teleological Transduction Theory developed in the previous volumes of the series, harmony of the Mind is a physical concept of normal functioning. Respectively, when the pathologies are described as dissonances, it is not a metaphor but a reference to the physical malfunction leading to the disintegration of the Mind. The book proposes a new approach to the diagnosis and classification of mental pathologies, based on an assessment of the state of the physical mechanism of the Mind and violations of the technological algorithm of the brain. The goal is to create the concept as a universal tool that can be used in various pathologies. The book offers a model of systemic pathologies such as autism and schizophrenia, which reveals the essence of the physical problem that causes the observed symptoms. This could be the beginning of a project that will overcome the current chaotic state of the field of psychopathology and harmonize our diagnosis and treatment of mental illness as disorders of the brain.

Author: Edgar Garcia-Rill
Publisher: Academic Press
ISBN: 0128179937
Category : Medical
Languages : en
Pages : 278

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Book Description
Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. - Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders - Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders - Covers multiple neurological disorders, including epilepsy, Alzheimer's disease, Parkinson's disease and autism

Author: Wolfgang Baer
Publisher: Routledge
ISBN: 1317212274
Category : Philosophy
Languages : en
Pages : 326

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Book Description
Conscious Action Theory provides a logical unification between the spirit and the material, by identifying reality as an event that processes personal experiences into explanatory memories, from which personal experiences are regenerated in a never-ending cycle of activity. Baer explores the idea that our personal feelings are undeniable facts that have been systematically excluded from the basic sciences, thereby leaving us with a schizophrenic division between objective materialism and spiritual idealism. Cognitive Action Theory (CAT) achieves this unification by recognizing that the observer’s existence is the foundational premise underlying all scientific inquiry. It develops as an event-oriented physical theory in which the first-person observer is central. By analyzing the methods through which we human observers gain knowledge and create the belief systems within which our experiences are explained, we discover a fundamental truth: all systems are observers and exhibit some form of internal awareness. Events, not the objects appearing in them, are the fundamental building blocks of reality. The book is comprised of three parts: the first addresses the paradigm shift from an object to an event-oriented world view, the second develops the foundations of action physics for an event-oriented world view and the third provides examples of how these new ideas can be applied to move our knowledge up the next evolutionary step of human development. This book will benefit anyone questioning their role in the universe, especially those in interdisciplinary fields of philosophy, psychology, neuroscience and medicine, who seek understanding of quantum theory as the physics of conscious systems that know the world.

Author: Eduardo E. Benarroch
Publisher: Oxford University Press
ISBN: 0190209429
Category : Medical
Languages : en
Pages : 850

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Book Description
Fully updated and revised according to student feedback, the sixth edition of Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level provides a systematic approach to anatomy, physiology, and pathology of the nervous system inspired by the neurologist's approach to solving clinical problems. This volume has 4 sections: 1) an overview of the neurosciences necessary for understanding anatomical localization and pathophysiologic characterization of neurologic disorders; 2) an approach to localizing lesions in the 7 longitudinal systems of the nervous system; 3) an approach to localizing lesions in the 4 horizontal levels of the nervous system; and 4) a collection of clinical problems. This book provides the neuroscience framework to support the neurologist in a clinical setting and is also a great resource for neurology and psychiatry board certifications. This is the perfect guide for all medical students and neurology, psychiatry, and physical medicine residents at early stages of training. New to This Edition - A chapter devoted to multiple-choice questions for self-assessment - Discussion of emerging concepts in molecular, cellular, and system neurosciences - New chapters on emotion and consciousness systems - Incorporation of new discoveries in neuroimaging and an appendix for tables of medications commonly used to treat neurologic disorders

Author: G. Buzsáki
Publisher: Oxford University Press
ISBN: 0199828237
Category : Medical
Languages : en
Pages : 465

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Book Description
Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.

Author: Rocco Salvatore Calabro
Publisher: Nova Science Pub Incorporated
ISBN: 9781626189409
Category : Science
Languages : en
Pages : 194

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Book Description
Chronic disorders of consciousness comprise a tragic group of conditions for which determining prognosis is a prerequisite for clinical decision-making. The Vegetative State (VS) and the Minimally Conscious State (MCS) are syndromes, encompassing a spectrum of severity with various etiologies, most commonly traumatic brain injury or hypoxic-ischemic or hemorrhagic neuronal injury. They can be a transient stage during recovery from an acute brain insult or can be chronic and stable, usually after a variable period of coma. Recent advances in neuroimaging are providing new insights into cerebral activity in patients with severe brain damage. The mapping of cognitive processes (mostly by measuring regional changes in blood flow, initially by PET and currently by fMRI, and by measuring regional metabolic changes by MRSI) is providing insight into the functional neuroanatomy and metabolic assessment of consciousness. However, differential diagnosis of SV and MCS is still difficult and their complex management involves many different and skilled healthcare professionals. This book is aimed at examining the pathophysiology of consciousness disorders with their multifaceted assessment and treatment, including new diagnostic tools and novel prognostic markers, and the important bioethical issues concerning "the end of life" and the "dignity of the person".

Author: Olivier Godefroy
Publisher: Cambridge University Press
ISBN: 1139461893
Category : Medical
Languages : en
Pages : 637

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Book Description
The care of stroke patients has changed dramatically. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioural and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management and the likelihood and significance of long-term disability. This book will appeal to all clinicians involved in the care of stroke patients, as well as to neuropsychologists, other rehabilitation therapists and research scientists investigating the underlying neuroscience.

Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258

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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.