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Author: Donald Earl Henson Publisher: ISBN: Category : Medical Languages : en Pages : 600
Book Description
A useful resource for the diagnosis and treatment of the early stages of cancer, this excellent book provides vital information for the early recognition of cancerous lesions. Coverage includes the lymphoid system, the small and large intestine, the central nervous system, soft tissue, bone, neuroblastoma, neuroendocrine, Wilms' tumor, the breast, kidney, and more. New to this edition is coverage of molecular pathology, many new chapters on different body sites, as well as many chapters completely rewritten by eminent authors, and new techniques throughout. Written by top-notch surgical pathologists who have extensive experience in each organ system or tissue area under study.Covers in detail the early stages of human cancer. Detailed discussions of clinical pathological features include information on DNA analysis by flow cytometry and its usefulness in diagnosis and prognosis.
Author: Donald Earl Henson Publisher: ISBN: Category : Medical Languages : en Pages : 600
Book Description
A useful resource for the diagnosis and treatment of the early stages of cancer, this excellent book provides vital information for the early recognition of cancerous lesions. Coverage includes the lymphoid system, the small and large intestine, the central nervous system, soft tissue, bone, neuroblastoma, neuroendocrine, Wilms' tumor, the breast, kidney, and more. New to this edition is coverage of molecular pathology, many new chapters on different body sites, as well as many chapters completely rewritten by eminent authors, and new techniques throughout. Written by top-notch surgical pathologists who have extensive experience in each organ system or tissue area under study.Covers in detail the early stages of human cancer. Detailed discussions of clinical pathological features include information on DNA analysis by flow cytometry and its usefulness in diagnosis and prognosis.
Author: Donald Earl Henson Publisher: Oxford University Press ISBN: 9780199771721 Category : Medical Languages : en Pages : 868
Book Description
Many malignant tumors have a morphologically recognizable precursor lesion. As screening and early detection have improved our ability to detect lesions at increasingly earlier stages of growth, an increased number of precancerous lesions are seen by pathologists. Unfortunately, a lack of uniform histologic criteria for precursors found in many organs can make diagnostic interpretation difficult. It is evident that physicians are seeking a better understanding of the genesis and progression of these lesions and their early biology, to provide optimal treatment and patient care. Pathology of Incipient Neoplasia 3E brings together all of the information available on the clinicopathologic features of precancerous lesions, defined to include atypical hyperplasias, in-situ changes, microinvasive or very small cancers in some sites, and other lesions recognized as potential precursors for invasive cancer. In some tissues, benign tumors may serve as precursors to malignant tumors, and therefore these also are considered. Organized by organ, each heavily-illustrated chapter is written by a well-recognized expert, to stress different facets of preneoplasia and minimally invasive tumors in that given tissue. Areas where strides have been made in research on molecular biologic aspects of neoplasia are discussed in conjunction with morphologic parameters. A chapter on salivary glands, and more than 350 color photos interspersed throughout the text, are new to this edition.
Author: Sudhir Srivastava Publisher: IOS Press ISBN: 9789051993738 Category : Medical Languages : en Pages : 512
Book Description
This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.
Author: Mark R. Wick Publisher: Cambridge University Press ISBN: 9781107022836 Category : Medical Languages : en Pages : 0
Book Description
Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.
Author: Gary J. Kelloff Publisher: Springer Science & Business Media ISBN: 1592597688 Category : Medical Languages : en Pages : 537
Book Description
Despite significant advances in cancer treatment and measures of neoplastic progression, drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic markers), and markers that measure cancer-associated morbidity is considerable, and overall prognosis as well as predict responses to specific therapy. cancer survival has remained relatively flat over the past All these biomarkers have the potential to greatly augment several decades (1,2). However, new technology the development of successful chemoprevention therapies, allowing exploration of signal transduction pathways, but two specific types of biomarkers will have the most identification of cancer-associated genes, and imaging of immediate impact on successful chemopreventive drug tissue architecture and molecular and cellular function is development—those that measure the risk of developing increasing our understanding of carcinogenesis and cancer invasive life-threatening disease, and those whose mo- progression. This knowledge is moving the focus of cancer lation can “reasonably predict” clinical benefit and, therapeutics, including cancer preventive treatments, to therefore, serve as surrogate endpoints for later-occurring drugs that take advantage of cellular control mechanisms clinical disease. Thus far, the biomarker that best measures to selectively suppress cancer progression. these two phenomena is intraepithelial neoplasia (IEN) Carcinogenesis is now visualized as a multifocal, because it is a near obligate precursor to cancer.
Author: David J. Kerr Publisher: Oxford University Press ISBN: 0191065110 Category : Medical Languages : en Pages : 2837
Book Description
Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.
Author: Curtis E. Margo Publisher: Elsevier ISBN: 0323957897 Category : Science Languages : en Pages : 402
Book Description
Ophthalmic Pathology: The Evolution of Current Concepts examines how our current understanding of morphologic disease, nomenclature and classification over the last century came about. The book explores the historical context and the modern trends of ocular nosology, emphasizing the science of disease classification. Chapters highlight major studies and developments surrounding approximately 50 disorders whose diagnoses are established by pathology, corresponding to a historical road map of current nomenclature, methods of disease classification, and the role of diagnostic morphology. Using a streamlined, highly illustrated format, this book provides a unique historic and evolutionary perspective into current views on the morphology of eye disease. - Includes illustrations showing basic principles and relevant morphologic features of different conditions - Provides insights into the limitations of morphologic diagnoses - Discusses a wide range of disorders, including ophthalmic pathology of the eye, conjunctiva and optic nerve
Author: Dani S. Zander Publisher: Elsevier Health Sciences ISBN: 0443067414 Category : Medical Languages : en Pages : 854
Book Description
By Dani S. Zander, MD, Professor and Vice Chair, Director of Anatomic Pathology, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX; and Carol F. Farver, MD, Staff Pathologist, Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH
Author: Donald Earl Henson
Author: Donald Earl Henson
Author: Donald Earl Henson
Author: Donald Earl Henson
Author: Sudhir Srivastava
Author: Alecsandru Ioan Baba
Author: Mark R. Wick
Author: Gary J. Kelloff
Author: David J. Kerr
Author: Curtis E. Margo
Author: Dani S. Zander