Pathogenesis of Wound and Biomaterial-Associated Infections

Pathogenesis of Wound and Biomaterial-Associated Infections PDF Author: Torkel Wadström
Publisher: Springer Science & Business Media
ISBN: 1447134540
Category : Technology & Engineering
Languages : en
Pages : 537

Book Description
Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.

Racing for the Surface

Racing for the Surface PDF Author: Bingyun Li
Publisher: Springer Nature
ISBN: 3030344754
Category : Medical
Languages : en
Pages : 648

Book Description
This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.

Wound Closure Biomaterials and Devices

Wound Closure Biomaterials and Devices PDF Author: Chih-Chang Chu
Publisher: CRC Press
ISBN: 9780849349645
Category : Medical
Languages : en
Pages : 416

Book Description
Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï Sutures and other wound closure devices, including absorbable sutures and their biodegradation properties ï The chemistry, physics, mechanics, biology, and biomaterials science of suture materials ï Tissue adhesive, ligating clips, and staplers ï The biomechanics and pathology of wound healing ï Future trends and new emerging materials in the treatment of wound closure

Burn Wound Infections

Burn Wound Infections PDF Author: Fatemeh Mottaghitalab
Publisher: Woodhead Publishing
ISBN: 0443335214
Category : Technology & Engineering
Languages : en
Pages : 0

Book Description
"Burn Wound Infections: Biomaterials, Healing Mechanisms, Dressing Techniques, and Clinical Practice" is a comprehensive resource that includes information about the use of different biomaterials and hydrogels for repairing infected wounds and their clinical outcomes. The book includes three parts - Part I: Burn wound infections: mechanisms, pathophysiology, and healing; Part II: Types of dressings used for infected burn wounds; and Part III: Regulatory Considerations and Commercialization of biomaterial/hydrogel based dressings for infected burn wound• Focuses on both clinical outcomes and commercialization• Presents a thorough overview of the current state of using biomaterial/hydrogel based dressing for infected burn wounds. This broad coverage ensures that readers are well-informed about the most significant developments in the field• Provides expert perspectives from leading authorities working in the field

Biofilm Infections

Biofilm Infections PDF Author: Thomas Bjarnsholt
Publisher: Springer
ISBN: 9781489982285
Category : Science
Languages : en
Pages : 0

Book Description
This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Therapeutic Dressings and Wound Healing Applications

Therapeutic Dressings and Wound Healing Applications PDF Author: Joshua Boateng
Publisher: John Wiley & Sons
ISBN: 1119433266
Category : Science
Languages : en
Pages : 444

Book Description
The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.

Biomaterial-Related Infections

Biomaterial-Related Infections PDF Author: Natália Martins
Publisher: MDPI
ISBN: 3039434381
Category : Medical
Languages : en
Pages : 204

Book Description
The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration.

Bioengineering In Wound Healing: A Systems Approach

Bioengineering In Wound Healing: A Systems Approach PDF Author: Martin L Yarmush
Publisher: World Scientific
ISBN: 9813144599
Category : Technology & Engineering
Languages : en
Pages : 394

Book Description
What is a wound, how does it heal, and how can we prevent scarring? The concept of wound healing has puzzled humans even before the advent of modern medicine.In recent years, bioengineering has tackled the problems of cancer, tissue engineering and molecular manufacturing. The broad spectrum of technologies developed in these fields could potentially transform the wound care practice. However, entering the world of wound healing research is challenging — a broad spectrum of knowledge is required to understand wounds and improve healing.This book provides an essential introduction of the field of wound healing to bioengineers and scientists outside the field of medicine. Written by leading researchers from various fields, this book is a comprehensive primer that gives readers a holistic understanding of the field of wound biology, diagnostics and treatment technologies.

Wound Healing and Skin Physiology

Wound Healing and Skin Physiology PDF Author: Peter Altmeyer
Publisher: Springer Science & Business Media
ISBN: 3642778828
Category : Medical
Languages : en
Pages : 701

Book Description
On the occasion of the European Congress on Wound Healing and Skin Physiology (Bochum, Germany, November 1992), an international team of scientists and clinicians discussed the core topics in this important field of dermatological and surgical research. Themes include morphology and physiology, microcirculation and angiogenesis, biochemistry and immunology, microbiology and wound infection, non-invasive measurement techniques, wound repair, surgical treatment, dressings, and agents that promote wound healing.

Biomaterials and Medical Device - Associated Infections

Biomaterials and Medical Device - Associated Infections PDF Author: L Barnes
Publisher: Elsevier
ISBN: 0857097229
Category : Medical
Languages : en
Pages : 281

Book Description
Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection. - Provides analysis of biofilms and their relevance to implant associated infections. - Assesses technologies for controlling biofilms. - Considers advantages and disadvantages of in vivo infection studies.