Parvoviruses and Human Disease PDF Download

Author: J. R. Pattison
Publisher: CRC Press
ISBN: 1351092308
Category : Science
Languages : en
Pages : 271

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Book Description
This book gives details of the discovery and research work on B19 virus to date. The virus is an autonomous parvovirus and many of its properties and much of its behaviour can be predicted from this. Accordingly, the detailed account of B19 viruses is set in the context of two general chapters on the nature of parvoviruses and the patterns of disease in animals produced by parvoviruses.

Author: Kenneth I. Berns
Publisher: Springer Science & Business Media
ISBN: 146848012X
Category : Medical
Languages : en
Pages : 419

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Book Description
The Parvoviridae have been of increasing interest to reseachers in the past decade. Their small size and simple structure have made them ame nable to detailed physiochemical analysis, and from this work relatively detailed information has resulted that has signficantly increased our un derstanding of the biology of these viruses. It has become clear that the Parvoviridae are of interest not only for their own sake, but also because their relative simplicity renders them useful probes in the study of the biology of host cells and of other DNA viruses with which they interact. The Dependovirus genus, for instance, contains the defective adeno-as sociated viruses (AA V), which require a coinfection with either an ad enovirus or a herpesvirus for productive multiplication. Studies of AA V, therefore, necessarily impinge on our understanding of the control of macromolecular synthesis by the helper virus. Similarly AA V has been reported to inhibit the oncogenicity of both adeno-and herpesviruses and has been used as a probe of mechanism in these instances as well. Finally, AA V establishes latent infections in vivo and is the only mammalian DNA virus where a comparable model system has been established in cell culture. This system has allowed study of the mechanism of latent infection at the molecular level."

Author: Steffen Faisst
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805569467
Category : Science
Languages : en
Pages : 220

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Book Description
Die einzelnen Kapitel sind hervorragend recherchiert und von Experten auf dem jeweiligen Gebiet bearbeitet. Insbesondere wird immer wieder auf die Molekularbiologie eingegangen, die bei diesen Viren einige Besonderheiten aufweist. Das Buch ist auf dem aktuellsten Stand der Forschung. Dies zeigen auch die zitierten Literaturstellen, die im wesentlichen aus den letzten Jahren stammen. So eignet sich dieses Buch insbesondere zum Nachschlagen bestimmter Phanomene und Eigenarten dieser Virusgruppe. Es sollte in keiner Bibliothek eines virologisch Interessierten fehlen.

Author: Jonathan Kerr
Publisher: CRC Press
ISBN: 0340811986
Category : Medical
Languages : en
Pages : 657

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Book Description
This comprehensive reference work brings together for the first time information on every aspect of the parvoviruses in a single volume. It presents the new system of parvovirus classification, as agreed by the International Committee for the Taxonomy of Viruses (ICTV), and includes cutting edge information on the virology, molecular and cellular biology, immunology and clinical manifestations of infection with each known and proposed member of the family Parvoviridae. The book also describes the rapidly expanding basic and clinical science which underpins gene therapy applications using helper-dependent and helper-independent parvoviruses. The respected editorial group has drawn together renowned contributors from around the world to produce what will undoubtedly become the standard reference on the subject. It is essential reading for clinical or research virologists and microbiologists, infectious disease specialists, and public health specialists and laboratories.

Author: John Ridley Pattison
Publisher: CRC PressI Llc
ISBN: 9780849359569
Category : Science
Languages : en
Pages : 181

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Book Description
A survey of current knowledge and experience of parvoviruses and human disease. The 13 contributors cover: the discovery of human parvoviruses; their nature; patterns of parvovirus disease in animals; laboratory tests for the diagnosis of infection with B19 virus; B19 virus infection and the aplastic crisis; rash illness; volunteer studies; studies in bone marrow cell culture; B19 infections in pregnancy; small round human fecal viruses; adeno-associated viruses of humans. Annotation copyrighted by Book News, Inc., Portland, OR

Author: Larry J. Anderson
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805563531
Category : Medical
Languages : en
Pages : 163

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Book Description
This book provides the reader with comprehensive and detailed reviews of subjects important to understanding parvovirus B19, including the structure and biochemistry of the virus, the clinical and epidemiological features of infection, the diagnosis of infection, the pathophysiology of disease, the host's immune response, and the treatment and prevention of disease. Its expert contributions make this publication an essential and timely resource for clinicians, epidemiologists and public health policymakers in their endeavor to optimize treatment and prevention. It will also be appreciated by laboratory researchers interested in the physical and biological properties of the virus and the pathogenesis of B19 disease.

Author: Giorgio Gallinella
Publisher: MDPI
ISBN: 3039283103
Category : Medical
Languages : en
Pages : 342

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Book Description
Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.

Author: Jane E. Sykes
Publisher: Elsevier Health Sciences
ISBN: 0323241948
Category : Medical
Languages : en
Pages : 928

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Book Description
Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health implications. Over 80 case studies illustrate how the information provided can be applied in everyday practice. Logical approach to laboratory diagnosis guides you through all the steps needed to accurately diagnose and treat viral, bacterial, fungal, protozoal, and algal diseases. Practical protocols provided by expert clinicians guide you in the management of canine and feline patients suspected to have infectious diseases, including handling, disinfection, isolation, and vaccination protocols. Over 500 full color images – geographic distribution maps, life cycle drawings, and hundreds of color photographs – visually illustrate and clarify complex issues. Easy-to-understand tables and boxes make content quickly accessible, eliminating the need to sort through dense text for critical information in the clinical setting.

Author: Christopher J. Burrell
Publisher: Academic Press
ISBN: 0123751578
Category : Science
Languages : en
Pages : 604

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Book Description
Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. Features updated and expanded coverage of pathogenesis and immunity Contains the latest laboratory diagnostic methods Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Author: Mei-Hwei Chang
Publisher: Springer
ISBN: 981130050X
Category : Medical
Languages : en
Pages : 227

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Book Description
This book is aimed to emphasize the rationale and importance of prevention and management of viral hepatitis in children, providing cutting edge knowledge. Viral hepatitis is a major health problem in the world. Although most complications of viral hepatitis are observed in adults, primary infection with hepatitis viruses often occurs during infancy or childhood. To better control viral hepatitis, prevention and therapy if possible should be started in childhood. This book offers updated and unique information about viral hepatitis in children, which has vitally important impact on global disease outcome and control, yet not discussed as frequently as viral hepatitis in adults in previous medical literature. Better prevention and management strategies are covered, starting from infancy and childhood, and even earlier during fetal life. It will be very helpful for better control of viral hepatitis both for daily practice and for developing future strategies and directions. If we can successfully control viral hepatitis in children, there will be very little remaining chronic hepatitis and related complications such as liver cirrhosis or hepatoma in adults. We hope readers, including medical students, researchers, pediatricians, family medicine physicians, infectious disease personnel, public health workers, gastroenterologists, hepatologists and parents of children with chronic hepatitis, will be benefited by reading this book.