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Author: Robert B. Darnell Publisher: OUP USA ISBN: 0199772738 Category : Medical Languages : en Pages : 497
Book Description
This text provides a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book provides an overview, classifying the disorders, describes a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general, and much more.
Author: Robert B. Darnell Publisher: OUP USA ISBN: 0199772738 Category : Medical Languages : en Pages : 497
Book Description
This text provides a comprehensive review of paraneoplastic syndromes from considering both clinical and pathophysiologic aspects. The book provides an overview, classifying the disorders, describes a clinical approach to the diagnosis and treatment of paraneoplastic syndromes in general, and much more.
Author: Robert C. Bast, Jr. Publisher: John Wiley & Sons ISBN: 111900084X Category : Medical Languages : en Pages : 2004
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: Publisher: Elsevier ISBN: 0128242175 Category : Medical Languages : en Pages : 498
Book Description
This book extensively reviews Paraneoplastic Neurological Syndromes in light of the most recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to causing diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. These two new developments have not been addressed in other volumes available on the market. Section 1 focuses on immunological defense mechanisms against tumors. Besides investigating the pathogenetic mechanisms of these disorders, this section will also explore what the introduction of new drugs used in immune checkpoint inhibitor cancer therapy is teaching us in terms of immunopathogenesis. The second section will present individual syndromes (phenotypical clinical manifestations) of the CNS, PNS, NMJ and muscle. These chapters will, however, be preceded by an epidemiological analysis and a chapter describing the clinical approach to patients with these disorders. Consideration will also be given in specific chapters to general therapeutic strategies and the techniques used to search for diagnostically relevant autoantibodies. Presentation of the individual diseases will be followed by a third section investigating the role of antibody markers, presented in three chapters differentiating cytoplasmic, nuclear and neuronal cell surface reactivities. The innovative component of the final two sections compared to previously published volumes lies in their presentation of the profile of paraneoplastic diseases by tumor type. Special attention will be given to thymoma (involved particularly with novel antibodies against surface antigens), and neuroendocrine tumours, which are as yet comparatively unexplored in the literature. Lastly, a clinical update will be provided on gynecological, hematological and testicular malignancies. The last section will address side effects of the new immuno-oncological drugs increasingly used in cancer therapy. The high number of neurological complications that occur when tumor checkpoints are inhibited against immune defences provides the ideal experimental model for understanding the pathogenesis of these diseases. Profiles paraneoplastic diseases by tumor type Identifies the pathogenetic mechanisms of PNS and provides epidemiological analysis Presents individual syndromes of the CNS, PNS, NMJ, and muscle Investigates the role of antibody markers Differentiates cytoplasmic, nuclear, and neuronal cell surface reactivities Discusses immune-oncological drugs causing diseases that are indistinguishable from PNS Reviews therapeutic strategies and clinical approach to PNS patients
Author: The American Cancer Society Publisher: John Wiley & Sons ISBN: 1118517644 Category : Medical Languages : en Pages : 727
Book Description
Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners comprehensively addresses all aspects of clinical management for cancer taking a balanced, authoritative and, -where possible- evidence-based stance and may be used in conjunction with the book, The American Cancer Society's Principles of Oncology: Prevention to Survivorship. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a practical understanding of the field of oncology.
Author: Publisher: Elsevier ISBN: 0444634460 Category : Science Languages : en Pages : 568
Book Description
Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities
Author: Karen Helton Rhodes Publisher: John Wiley & Sons ISBN: 1119337224 Category : Medical Languages : en Pages : 868
Book Description
Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Dermatology, Third Edition offers accessible, reliable information on canine and feline dermatology using the popular Blackwell's Five-Minute Veterinary Consult format—now with new topics, updated therapeutics, and improved images. Provides fast access to reliable information on treating dermatologic diseases and conditions in dogs and cats Uses the popular Blackwell's Five-Minute Veterinary Consult format and alphabetic arrangement for quick reference Offers thorough updates to this popular handbook, including a new “basics” section, new topics, and updated therapeutics, as well as new and improved images of dermatoses for easy comparison with clinical cases Puts the most commonly used dermatology information at the clinician's fingertips for rapid decision-making Includes access to a companion website with client education handouts to download and use in practice
Author: Fred F. Ferri Publisher: Elsevier Health Sciences ISBN: 0323679773 Category : Medical Languages : en Pages : 2136
Book Description
Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri’s Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today’s medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.
Author: Douglas B. Evans Publisher: Springer Science & Business Media ISBN: 0387216006 Category : Medical Languages : en Pages : 413
Book Description
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
Author: Ursula Rüther Publisher: S. Karger AG (Switzerland) ISBN: Category : Medical Languages : en Pages : 280
Book Description
Paraneoplastic syndromes comprise a variety of signs and symptoms that are not directly caused by the primary tumor or its metastases. They may be metabolic, dystrophic or degenerative disorders resulting from remote humoral or hormonal effects, and spontaneously disappear after successful tumor excision or chemo- or radiotherapy. A few years ago, paraneoplastic syndromes were still thought to be rare. Today, we know that a single tumor is capable of producing a variety of hormones and that paraneoplastic syndromes are caused by this ectopic formation of hormones, hormone-like polypeptides, and growth factors. Recent research has shown that viral metabolic intermediates, mutated oncogenes, and suppressor genes may also be involved. The early diagnosis of a paraneoplastic syndrome is crucial, for it may point to an undetected tumor or signal tumor relapse. This book covers endocrinal, neurologic, muscular, cutaneous, hematologic and organ-associated paraneoplastic syndromes and provides a detailed description of their clinical symptoms, diagnosis and therapy. Aiming to promote the understanding of paraneoplastic syndromes, this volume is an indispensable source for their diagnosis and treatment in clinical oncology.