Author:
Publisher:
ISBN:
Category : Artists, Australian
Languages : en
Pages :
Book Description
Kate Butler
Papers Presented at the Boston, Massachusetts Meeting
Author: American Chemical Society. Division of Polymeric Materials: Science and Engineering. Meeting
Publisher:
ISBN: 9781605600192
Category : Polymeric composites
Languages : en
Pages : 994
Book Description
Publisher:
ISBN: 9781605600192
Category : Polymeric composites
Languages : en
Pages : 994
Book Description
Virtual Screening
Author: Christoph Sotriffer
Publisher: John Wiley & Sons
ISBN: 3527633340
Category : Medical
Languages : en
Pages : 774
Book Description
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable degree of accuracy. Alternatively, if active ligands are already available, molecular similarity searches can be used to find new molecules. This virtual screening can even be applied to compounds that have yet to be synthesized, as opposed to "real" screening that requires cost- and labor-intensive laboratory testing with previously synthesized drug compounds. Unique in its focus on the end user, this is a real "how to" book that does not presuppose prior experience in virtual screening or a background in computational chemistry. It is both a desktop reference and practical guide to virtual screening applications in drug discovery, offering a comprehensive and up-to-date overview. Clearly divided into four major sections, the first provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of this technique. The third and fourth, practical parts contain practical guidelines and several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout the text, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods.
Publisher: John Wiley & Sons
ISBN: 3527633340
Category : Medical
Languages : en
Pages : 774
Book Description
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable degree of accuracy. Alternatively, if active ligands are already available, molecular similarity searches can be used to find new molecules. This virtual screening can even be applied to compounds that have yet to be synthesized, as opposed to "real" screening that requires cost- and labor-intensive laboratory testing with previously synthesized drug compounds. Unique in its focus on the end user, this is a real "how to" book that does not presuppose prior experience in virtual screening or a background in computational chemistry. It is both a desktop reference and practical guide to virtual screening applications in drug discovery, offering a comprehensive and up-to-date overview. Clearly divided into four major sections, the first provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of this technique. The third and fourth, practical parts contain practical guidelines and several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout the text, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods.
Inside Cultures
Author: William Balée
Publisher: Routledge
ISBN: 1315426471
Category : Social Science
Languages : en
Pages : 542
Book Description
This concise, contemporary, and inexpensive option for instructors of cultural anthropology breaks away from the traditional structure of introductory textbooks. Emphasizing the interaction between humans and their environment, the tension between human universals and cultural variation, and the impacts of colonialism on traditional cultures, Inside Cultures shows students how cultural anthropology can help us understand the complex, globalized world around us. This second edition: includes brand new material on a variety of subjects, including genomic studies, race and racism, cross-cultural issues of gender identity, terrorism and ethnography, and business anthropology; presents updated and enhanced discussions of medical anthropology, European colonialism and disease, the Atlantic slave trade, and much more; offers personal stories of the author’s fieldwork in Amazonia, sidebars illustrating fascinating cases of cultures in action, and other pedagogical elements such as timelines; is written is clear, supple prose that delights readers while informing them
Publisher: Routledge
ISBN: 1315426471
Category : Social Science
Languages : en
Pages : 542
Book Description
This concise, contemporary, and inexpensive option for instructors of cultural anthropology breaks away from the traditional structure of introductory textbooks. Emphasizing the interaction between humans and their environment, the tension between human universals and cultural variation, and the impacts of colonialism on traditional cultures, Inside Cultures shows students how cultural anthropology can help us understand the complex, globalized world around us. This second edition: includes brand new material on a variety of subjects, including genomic studies, race and racism, cross-cultural issues of gender identity, terrorism and ethnography, and business anthropology; presents updated and enhanced discussions of medical anthropology, European colonialism and disease, the Atlantic slave trade, and much more; offers personal stories of the author’s fieldwork in Amazonia, sidebars illustrating fascinating cases of cultures in action, and other pedagogical elements such as timelines; is written is clear, supple prose that delights readers while informing them
PMSE Preprints, Volume 97, Fall 2007
Author: American Chemical Society Division of Polymeric Materials Science and Engineering
Publisher:
ISBN:
Category :
Languages : en
Pages : 497
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 497
Book Description
Paper and Timber
NBS Building Science Series
Hydrogen Production
Performance Criteria for Solar Heating and Cooling Systems in Residential Buildings
Author:
Publisher:
ISBN:
Category : Dwellings
Languages : en
Pages : 244
Book Description
This performance criteria, developed for the Department of Housing and Urban Development, is a baseline document for criteria and standards for the design, development, technical evaluation, and procurement of solar heating and cooling systems for residential buildings in accordance with the requirements of Section 8 of Public Law 93-409, the 'Solar Heating and Cooling Demonstration Act of 1974.' The document is intended to establish minimum levels of performance with regard to health and safety and the various aspects of technical performance. The criteria for health and safety put primary emphasis on compliance with existing codes and standards. The criteria on thermal and mechanical performance, durability/reliability and operation/servicing present performance requirements considered to be representative of acceptable levels.
Publisher:
ISBN:
Category : Dwellings
Languages : en
Pages : 244
Book Description
This performance criteria, developed for the Department of Housing and Urban Development, is a baseline document for criteria and standards for the design, development, technical evaluation, and procurement of solar heating and cooling systems for residential buildings in accordance with the requirements of Section 8 of Public Law 93-409, the 'Solar Heating and Cooling Demonstration Act of 1974.' The document is intended to establish minimum levels of performance with regard to health and safety and the various aspects of technical performance. The criteria for health and safety put primary emphasis on compliance with existing codes and standards. The criteria on thermal and mechanical performance, durability/reliability and operation/servicing present performance requirements considered to be representative of acceptable levels.
Routledge Handbook of Japanese Culture and Society
Author: Victoria Bestor
Publisher: Taylor & Francis
ISBN: 1136736271
Category : History
Languages : en
Pages : 336
Book Description
This Handbook is an interdisciplinary resource that focuses on contemporary Japan and the social and cultural trends that are important at the beginning of the twenty-first century.
Publisher: Taylor & Francis
ISBN: 1136736271
Category : History
Languages : en
Pages : 336
Book Description
This Handbook is an interdisciplinary resource that focuses on contemporary Japan and the social and cultural trends that are important at the beginning of the twenty-first century.