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Translational Pain Research

Translational Pain Research PDF Author: Lawrence Kruger
Publisher: CRC Press
ISBN: 1439812101
Category : Health & Fitness
Languages : en
Pages : 458

Book Description
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Translational Pain Research

Translational Pain Research PDF Author: Lawrence Kruger
Publisher: CRC Press
ISBN: 1439812101
Category : Health & Fitness
Languages : en
Pages : 458

Book Description
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Pain Research Progress

Pain Research Progress PDF Author: Fengrui Hu
Publisher: Nova Publishers
ISBN: 9781600216794
Category : Health & Fitness
Languages : en
Pages : 238

Book Description
Pain is an unpleasant sensation. It is defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage". Pain is part of the body's defence system: it triggers mental problem-solving strategies that seek to end the painful experience, and it promotes learning, making repetition of the painful situation less likely. The nociceptive system transmits signals that usually trigger the sensation of pain, it is a critical component of the body's ability to react to damaging stimuli and it is part of a rapid-warning relay instructing the central nervous system to initiate reactions for minimising injury. This book presents the latest research in the field from around the globe.

Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309459575
Category : Medical
Languages : en
Pages : 483

Book Description
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Psychological Mechanisms of Pain and Analgesia

Psychological Mechanisms of Pain and Analgesia PDF Author: Donald D. Price
Publisher: Progress in Pain Research and
ISBN:
Category : Medical
Languages : en
Pages : 272

Book Description


Narrative, Pain, and Suffering

Narrative, Pain, and Suffering PDF Author: Daniel B. Carr
Publisher: IAS Publishing
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 384

Book Description
When I experience pain, who or what is the me that suffers? When I relieve another's pain, who or what is the other that I restore to well-being? Increasingly, these questions seem answerable only through an understanding of narrative. Studies of pain narrative focus not simply on engrossing tales, but on complex and subtle processes rooted in the neurobiology of self-representation, emotion, and social interaction. These processes shape how individuals and cultures experience and report pain. Studies of narrative in its broadest sense not only deepen our understanding of pain and suffering, but also teach us about meaning, motivation, and discourse as represented in the biomedical, human, and social sciences. This book embodies the path-breaking multidisciplinary perspective that was created when leading contributors in neurobiology, integrative physiology, anthropology, psychology, sociology, and clinical research joined with clinicians, writers, and journalists from developed and developing countries. Together they have produced a unique volume that speaks to core issues integral to emerging pain research and humane health care in the 21st century.

Relieving Pain in America

Relieving Pain in America PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030921484X
Category : Medical
Languages : en
Pages : 383

Book Description
Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

CRPS

CRPS PDF Author: Peter R. Wilson
Publisher:
ISBN:
Category : Reflex sympathetic dystrophy
Languages : en
Pages : 336

Book Description
Complex regional pain syndrome is a medically and economically significant condition that is disproportionate to the inciting event. Until now, it has been difficult to make the diagnosis, but this volume presents validated diagnostic criteria for the condition. Treatment for the condition has been hampered by the lack of good clinical evidence. This volume summarizes all reported treatments and evaluates the scientific evidence for each. A treatment algorithm is presented. This is a text that will be invaluable for the clinician, and for all those who address the issues of CRPS in the medical, rehabilitation, public health, or medicolegal fields.

Advances in Pain Research

Advances in Pain Research PDF Author: Bai-Chuang Shyu
Publisher: Advances in Experimental Medic
ISBN: 9789811346767
Category : Medical
Languages : en
Pages : 276

Book Description
This book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for scientists to present recent findings in pain research and discuss research orientation in this field. APS 2017 focused on novel strategies for pain treatment. Written by experts from various disciplines, from molecular to functional, and from basic to clinic studies, this book is composed of 18 review articles on the physiology and pathology of pain in these research fields. Specific topics include circuitry, neurotransmitter, physiology, behavior, neuropathology, pharmacology, and the treatments for neuropathic pain disorders. The book is a valuable resource for researchers and graduate students in pain medicine and neuroscience.

Experiencing Pain

Experiencing Pain PDF Author: Sabrina Coninx
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110688409
Category : Philosophy
Languages : en
Pages : 200

Book Description
Although pain is one of the most fundamental and unique experiences we undergo in everyday life, it also constitutes one of the most enigmatic and frustrating subjects for many scientists. This book provides a detailed analysis of why this issue is grounded in the nature of pain itself. It also offers a philosophically driven solution of how we may still approach pain in a theoretically compelling and practically useful manner. Two main theses are defended: (i) Pain seems inscrutable because there exists no property that is commonly shared by all types of pain and that is at the same time particular to pain, setting it apart from other bodily sensations. This applies irrespective of whether we consider the psychological dimensions, neural networks, causal relations or biological functions of pain. Consequently, it is impossible to refer to ideal far-reaching and ideal distinct generalizations on the matter of pain. (ii) Despite this challenge, by focusing on the resemblance relations that hold across pains, we can generate scientific progress in explaining, predicting and treating pain. In doing so, the book aims to provide a clear conceptual basis for interdisciplinary communication and a useful heuristic for future research.

Explain Pain

Explain Pain PDF Author: David S Butler
Publisher: Noigroup Publications
ISBN: 0987342673
Category : Health & Fitness
Languages : en
Pages : 138

Book Description
Imagine an orchestra in your brain. It plays all kinds of harmonious melodies, then pain comes along and the different sections of the orchestra are reduced to a few pain tunes. All pain is real. And for many people it is a debilitating part of everyday life. It is now known that understanding more about why things hurt can actually help people to overcome their pain. Recent advances in fields such as neurophysiology, brain imaging, immunology, psychology and cellular biology have provided an explanatory platform from which to explore pain. In everyday language accompanied by quirky illustrations, Explain Pain discusses how pain responses are produced by the brain: how responses to injury from the autonomic motor and immune systems in your body contribute to pain, and why pain can persist after tissues have had plenty of time to heal. Explain Pain aims to give clinicians and people in pain the power to challenge pain and to consider new models for viewing what happens during pain. Once they have learnt about the processes involved they can follow a scientific route to recovery. The Authors: Dr Lorimer Moseley is Professor of Clinical Neurosciences and the Inaugural Chair in Physiotherapy at the University of South Australia, Adelaide, where he leads research groups at Body in Mind as well as with Neuroscience Research Australia in Sydney. Dr David Butler is an international freelance educator, author and director of the Neuro Orthopaedic Institute, based in Adelaide, Australia. Both authors continue to publish and present widely.