Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470514914
Category : Nature
Languages : en
Pages : 346
Book Description
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregulation, and neuroendocrine function. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.
P2 Purinoceptors
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470514914
Category : Nature
Languages : en
Pages : 346
Book Description
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregulation, and neuroendocrine function. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.
Publisher: John Wiley & Sons
ISBN: 0470514914
Category : Nature
Languages : en
Pages : 346
Book Description
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregulation, and neuroendocrine function. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.
Functional Expression of P2 Purinoceptors in a Primary Neuroglial Cell Culture of the Rat Arcuate Nucleus
Structure and Function of P2-purinoceptors
The P2 Nucleotide Receptors
Author: John T. Turner
Publisher: Springer Science & Business Media
ISBN: 1461218004
Category : Science
Languages : en
Pages : 439
Book Description
A state-of-the-art summary from leading laboratories around the world of our current knowledge of the molecular biology, the physiology, and the pharmacology of the P2 receptors. The authoritative contributions cover the major aspects of these receptors, describing the relationships between physiological and pharmacological effects of ATP and other nucleotides and the various cloned P2 receptors, as well as providing an historical perspective and discussing current issues of nomenclature. They also illuminate how P2 receptor structures contribute to their function, including the physical differences underlying the pharmacological and functional variations among P2 receptor subtypes.
Publisher: Springer Science & Business Media
ISBN: 1461218004
Category : Science
Languages : en
Pages : 439
Book Description
A state-of-the-art summary from leading laboratories around the world of our current knowledge of the molecular biology, the physiology, and the pharmacology of the P2 receptors. The authoritative contributions cover the major aspects of these receptors, describing the relationships between physiological and pharmacological effects of ATP and other nucleotides and the various cloned P2 receptors, as well as providing an historical perspective and discussing current issues of nomenclature. They also illuminate how P2 receptor structures contribute to their function, including the physical differences underlying the pharmacological and functional variations among P2 receptor subtypes.
Investigations Into the Properties of Vascular P2-purinoceptors
Regulatory Function of Adenosine
Author: Robert M. Berne
Publisher: Springer Science & Business Media
ISBN: 146133909X
Category : Medical
Languages : en
Pages : 557
Book Description
The principal objective of this symposium was to bring together investigators from all over the world who work in diverse areas of research but share a common interest in the physiologic and pathophysiologic funetions of the nueleoside adenosine. In 1978, the "International Conference on Physiological and Regulatory Funetions of Adenosine and Adenine Nueleotides," held in Banff, Canada, served as an effective catalyst in enabling scientists with differ ent points of view to exchange information and ideas on this subject. Since 1978, the amount of research on different as peets of adenosine metabolism, mechanism of action, transport, and function in various tissues (in both nor maI and abnormal states) has increased exponentially, and there was an urgent need for another meeting for updating information on this burgeoning subject. The focus of the meeting was extremely sharp, but the scope of the subject material was very broad. Scientists categorized as chemists, biochemists, physiologists, pharmacologists, and immunologists, working with cells and eelI fragments, with tissues such as heart, brain, musele, fat, kidney, and with human beings having immune deficiency diseases participated in the sym posium. They had an opportunity to air their differences, reinforce their areas of agreement, and, most important, they educated each other with respeet to research on adenosine; it is hoped that they also enriched their own research programs from the information they gained from their fellow participants.
Publisher: Springer Science & Business Media
ISBN: 146133909X
Category : Medical
Languages : en
Pages : 557
Book Description
The principal objective of this symposium was to bring together investigators from all over the world who work in diverse areas of research but share a common interest in the physiologic and pathophysiologic funetions of the nueleoside adenosine. In 1978, the "International Conference on Physiological and Regulatory Funetions of Adenosine and Adenine Nueleotides," held in Banff, Canada, served as an effective catalyst in enabling scientists with differ ent points of view to exchange information and ideas on this subject. Since 1978, the amount of research on different as peets of adenosine metabolism, mechanism of action, transport, and function in various tissues (in both nor maI and abnormal states) has increased exponentially, and there was an urgent need for another meeting for updating information on this burgeoning subject. The focus of the meeting was extremely sharp, but the scope of the subject material was very broad. Scientists categorized as chemists, biochemists, physiologists, pharmacologists, and immunologists, working with cells and eelI fragments, with tissues such as heart, brain, musele, fat, kidney, and with human beings having immune deficiency diseases participated in the sym posium. They had an opportunity to air their differences, reinforce their areas of agreement, and, most important, they educated each other with respeet to research on adenosine; it is hoped that they also enriched their own research programs from the information they gained from their fellow participants.
Receptors P1 and P2 as Targets for Drug Therapy in Humans
Author: Robson Faria
Publisher: BoD – Books on Demand
ISBN: 1789845343
Category : Medical
Languages : en
Pages : 112
Book Description
This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
Publisher: BoD – Books on Demand
ISBN: 1789845343
Category : Medical
Languages : en
Pages : 112
Book Description
This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
Pharmacology of Purine and Pyrimidine Receptors
Author:
Publisher: Academic Press
ISBN: 0123855330
Category : Science
Languages : en
Pages : 558
Book Description
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
Publisher: Academic Press
ISBN: 0123855330
Category : Science
Languages : en
Pages : 558
Book Description
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
Autonomic Pharmacology
Author: Kenneth J Broadley
Publisher: CRC Press
ISBN: 1135741395
Category : Medical
Languages : en
Pages : 612
Book Description
This overview of autonomic pharmacology describes the anatomy, physiology and pharmacology of the autonomic involuntary nervous system. Covering the diverse group of drugs acting on the autonomous nervous system, their actions are reviewed together with their clinical uses, side effects, interactions and subcellular mechanisms of action. Information is organized in a logical flow, bringing together the latest advances in an integrated form on topics usually found only in a fragmented form.; This work is intended for all those researching in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry and molecular biology.
Publisher: CRC Press
ISBN: 1135741395
Category : Medical
Languages : en
Pages : 612
Book Description
This overview of autonomic pharmacology describes the anatomy, physiology and pharmacology of the autonomic involuntary nervous system. Covering the diverse group of drugs acting on the autonomous nervous system, their actions are reviewed together with their clinical uses, side effects, interactions and subcellular mechanisms of action. Information is organized in a logical flow, bringing together the latest advances in an integrated form on topics usually found only in a fragmented form.; This work is intended for all those researching in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry and molecular biology.
Characterisation of P2 Purinoceptors on Vascular Endothelial Cells
Author: Graeme Francis Wilkinson
Publisher:
ISBN:
Category : Endothelium
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category : Endothelium
Languages : en
Pages : 0
Book Description