Author: Val Vallyathan
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393
Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Oxygen/Nitrogen Radicals: Cell Injury and Disease
Author: Val Vallyathan
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393
Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393
Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.
Signaling Mechanisms of Oxygen and Nitrogen Free Radicals
Author: Igor B. Afanas'ev
Publisher: CRC Press
ISBN: 1420073753
Category : Medical
Languages : en
Pages : 230
Book Description
Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regu
Publisher: CRC Press
ISBN: 1420073753
Category : Medical
Languages : en
Pages : 230
Book Description
Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regu
Oxygen/Nitrogen Radicals and Cellular Injury
Author: Kenneth B. Adler
Publisher: DIANE Publishing
ISBN: 0788185381
Category :
Languages : en
Pages : 142
Book Description
Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.
Publisher: DIANE Publishing
ISBN: 0788185381
Category :
Languages : en
Pages : 142
Book Description
Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.
Oxygen/Nitrogen Radicals
Author: Val Vallyathan
Publisher: CRC Press
ISBN: 9780824748746
Category : Medical
Languages : en
Pages : 550
Book Description
The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.
Publisher: CRC Press
ISBN: 9780824748746
Category : Medical
Languages : en
Pages : 550
Book Description
The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.
Oxygen/nitrogen Radicals
Oxygen/nitrogen Radicals and Cellular Injury
Author: Kenneth B. Adler
Publisher:
ISBN:
Category : Antioxidants
Languages : en
Pages : 160
Book Description
Publisher:
ISBN:
Category : Antioxidants
Languages : en
Pages : 160
Book Description
Oxygen Radicals and Lung Injury
Intramolecular Reactions of Nitrogen-centered Radicals
Oxygen Radicals in Biology and Medicine
Author: Michael Simic
Publisher: Springer Science & Business Media
ISBN: 1468455680
Category : Science
Languages : en
Pages : 1064
Book Description
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
Publisher: Springer Science & Business Media
ISBN: 1468455680
Category : Science
Languages : en
Pages : 1064
Book Description
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
Free Radicals
Author: Neville A. Punchard
Publisher: IRL Press
ISBN: 9780199635597
Category : History
Languages : en
Pages : 310
Book Description
With the recognition that oxygen and nitrogen radicals are involved in normal cell metabolism, free radical research has begun to feature in most disciplines in the life sciences. Increasingly, their implication in a number of human disease processes is being accepted, altough conclusive evidence is lacking in many instances, partly due to the difficulties in detecting and measuring free radicals that have lifetimes measured in microseconds. This book outlines the latest techniques for quantifying radicals and their effects, and features detailed protocols, hints, and tips for success, troubleshooting comments, sample data, and key literature citations.
Publisher: IRL Press
ISBN: 9780199635597
Category : History
Languages : en
Pages : 310
Book Description
With the recognition that oxygen and nitrogen radicals are involved in normal cell metabolism, free radical research has begun to feature in most disciplines in the life sciences. Increasingly, their implication in a number of human disease processes is being accepted, altough conclusive evidence is lacking in many instances, partly due to the difficulties in detecting and measuring free radicals that have lifetimes measured in microseconds. This book outlines the latest techniques for quantifying radicals and their effects, and features detailed protocols, hints, and tips for success, troubleshooting comments, sample data, and key literature citations.