Oxidative Stress and Antioxidant Defenses in Biology PDF Download

Author: Sami Ahmad
Publisher: Springer Science & Business Media
ISBN: 1461596890
Category : Science
Languages : en
Pages : 478

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Book Description
This volume provides a comprehensive treatment of the latest research on oxidative stress and antioxidant defenses in all types of aerobic organisms. This book investigates oxidative stress in prokaryotes, protists, plants, fungi, vertebrates, and invertebrates, stimulating cross-fertilization among diverse fields. In addition, it explains the basic science of oxygen activation and oxidative stress as a foundation for more advanced material, making this book useful as a resource for both specialists and non-specialists.

Author: Donald Armstrong
Publisher: John Wiley & Sons
ISBN: 111883240X
Category : Science
Languages : en
Pages : 742

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Book Description
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Author: Tariq Aftab
Publisher: Springer Nature
ISBN: 9811679819
Category : Science
Languages : en
Pages : 458

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Book Description
This edited book highlights the molecular basis of various enzymatic and non-enzymatic antioxidants, defense mechanisms and adaptation strategies employed by plants to avoid the stressful conditions. Special focus is given to gene expression, omics and other latest technologies such as CRISPR-Cas mediated genome editing applications for defense related studies in plants. Environmental stresses such as drought, salinity or floods etc. induce the generation of reactive oxygen species (ROS) which causes severe damage to cell membrane integrity by accelerating lipid peroxidation. To counteract the detrimental effect of ROS, plants are inherited with an intricate and vibrant antioxidant defense system, comprised of enzymatic (catalase, peroxidase, superoxide dismutase, glutathione reductase, glutathione S-transferase, guaiacol peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase etc.), and non-enzymatic (glutathione, ascorbate, α-tocopherol, carotenoids, flavonoids etc.) antioxidants, which scavenge and/or reduce excess ROS and improve plant tolerance to various stresses. Stress tolerance in most crop plants is positively correlated with an efficient antioxidant system. Therefore, studying the efficiency of antioxidant defense systems in plants is necessary for facilitating the plant’s nature of adaptation against challenging environments. This book is of interest to teachers, researchers and academic experts. Also, the book serves as additional reading material for undergraduate and graduate students of biotechnology and molecular biology of plants.

Author: POLI
Publisher: Birkhäuser
ISBN: 3034891164
Category : Science
Languages : en
Pages : 540

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Book Description
Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description

Author: Tahira Farooqui
Publisher: John Wiley & Sons
ISBN: 1118148118
Category : Science
Languages : en
Pages : 433

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Book Description
This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy. It offers comprehensive reviews of the current understanding of oxidative stress-mediated physiology and pathology as well as directions for future research. It also provides current information on the role of oxidative stress in neurodegenerative diseases, cardiovascular diseases, and various types of cancer mediated by oxidative stress.

Author: Ching Kuang Chow
Publisher: CRC Press
ISBN: 1000697304
Category : Medical
Languages : en
Pages : 313

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Book Description
First Published in 1988, this three volume set offers a full insight into the immune system and its response to antioxidants. Carefully compiled and filled with diagrams, references and information this set is recommended for students of immunology and other professionals in their respective fields.

Author: Helaine M. Alessio
Publisher: Imperial College Press
ISBN: 1860949126
Category : Medical
Languages : en
Pages : 185

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Book Description
This book brings together some of the leading researchers in the actively investigated field of oxidative stress, an area of study which is of importance to human health and disease. It examines oxidative stress in a variety of models, at rest and after exercise, in young and old. Key concepts of oxidative stress, exercise and aging are presented in clear and easy-to-understand terms. Oxidative stress in different types of exercises OCo isometric, isotonic and sports OCo is explained in detail, with several chapters focusing on acute and chronic adaptations of skeletal muscles following both aerobic and non-aerobic exercises. The book includes current knowledge of the underlying mechanisms influencing health and disease processes associated with oxidative stress. Contents: Chemistry of Reactive Oxygen Species and Antioxidants (D C Close & A E Hagerman); Oxidative Stress in Plants and Animals (D C Close & A E Hagerman); The Exercise Continuum (R L Wiley); Oxidative Stress and Muscle Size, Type, and Action (H M Alessio); Oxidative Stress Across the Exercise Continuum (H M Alessio); Oxidative Stress and Antioxidant Defense: Effects of Aging and Exercise (L L Ji); Muscle, Oxidative Stress and Aging (J S Moylan et al.); Aging, Exercise, Antioxidants, and Cardioprotection (J Quindry & S Powers); Genetic Expressions: Oxidative Stress, Exercise, and Aging (N B Schweitzer & H M Alessio). Readership: Academics, researchers, upper undergraduate and graduate students in biochemistry, biological chemistry, physiology, gerontology, and cell & molecular biology; companies that develop and market products for sports, health, antioxidants and anti-aging interventions."

Author:
Publisher: BoD – Books on Demand
ISBN: 1838801251
Category : Science
Languages : en
Pages : 140

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Book Description
The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.

Author: M. Iqbal R. Khan
Publisher: Springer
ISBN: 9811052549
Category : Science
Languages : en
Pages : 336

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Book Description
The present edited book is an attempt to update the state of art of the knowledge on metabolism of ROS and antioxidants and their relationship in plant adaptation to abiotic stresses involving physiological, biochemical and molecular processes. The chapters are much focused on the current climate issues and how ROS metabolism can manipulate with antioxidant system to accelerate detoxification mechanism. It will enhance the mechanistic understanding on ROS and antioxidants system and will pave the path for agricultural scientists in developing tolerant crops to achieve sustainability under the changing environmental conditions. The increase in abiotic stress factors has become a major threat to sustainability of crop production. This situation has led to think ways which can help to come out with potential measures; for which it is necessary to understand the influence of abiotic stress factors on crops performance and the mechanisms by which these factors impact plants. It has now become evident that abiotic stress impacts negatively on plant growth and development at every stage of plant’s life. Plants adapt to the changing environment with the adjustment at physiological, biochemical and molecular levels. The possible mechanisms involved in the negative effects of abiotic stress factors are excess production of reactive oxygen species (ROS). They alter physiological and molecular mechanisms leading to poor performance of plants. Plants however, are able to cope with these adverse effects by inducing antioxidant systems as the priority. Nevertheless, the dual role of ROS has now been ascertained which provides an evidence for regulation of plant metabolism positively on a concentration-dependent manner. Under conditions of high ROS production, the antioxidant system plays a major role in diminishing the effects of ROS. Thus, ROS production and antioxidant system are interwoven with abiotic stress conditions. The antioxidants have the capacity to hold the stability in metabolism in order to avoid disruption due to environmental disturbances.