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Author: DR. HAKIM. SABOOWALA Publisher: Dr.Hakim Saboowala ISBN: Category : Medical Languages : en Pages : 35
Book Description
Cochlear gene therapy has undergone tremendous advances over the past decade. Beginning with some groundbreaking work in 2005 documenting hair cell regeneration using virally mediated delivery of the mouse atonal 1 gene, gene therapy is now being explored as a possible treatment for a variety of causes of hearing loss. Recent advances in cochlear gene therapy include improved methods of gene delivery with a better delineation of viral vectors that are suitable for this purpose, additional improvements in hair cell regeneration, and directed research towards: · Autoimmune hearing loss, · Ototoxicity, · Spiral ganglion survival, and · Genetic forms of hearing loss. If successful, cochlear gene therapy will dramatically alter our ability to treat a variety of forms of acquired and genetic hearing loss. An attempt has been made in this Booklet to highlight recent advances in cochlear gene therapy over the past several years. ….. Dr. H.K.Saboowala.M.B.(Bom) M.R.S.H.(London)
Author: DR. HAKIM. SABOOWALA Publisher: Dr.Hakim Saboowala ISBN: Category : Medical Languages : en Pages : 35
Book Description
Cochlear gene therapy has undergone tremendous advances over the past decade. Beginning with some groundbreaking work in 2005 documenting hair cell regeneration using virally mediated delivery of the mouse atonal 1 gene, gene therapy is now being explored as a possible treatment for a variety of causes of hearing loss. Recent advances in cochlear gene therapy include improved methods of gene delivery with a better delineation of viral vectors that are suitable for this purpose, additional improvements in hair cell regeneration, and directed research towards: · Autoimmune hearing loss, · Ototoxicity, · Spiral ganglion survival, and · Genetic forms of hearing loss. If successful, cochlear gene therapy will dramatically alter our ability to treat a variety of forms of acquired and genetic hearing loss. An attempt has been made in this Booklet to highlight recent advances in cochlear gene therapy over the past several years. ….. Dr. H.K.Saboowala.M.B.(Bom) M.R.S.H.(London)
Author: Allen F. Ryan Publisher: Karger Medical and Scientific Publishers ISBN: 3805590350 Category : Medical Languages : en Pages : 127
Book Description
This volume reviews current concepts and recent research findings of the application of gene therapy to the inner ear. Various forms of gene therapy, disorders that are potential targets for gene therapy, techniques for gene delivery, and mechanisms of gene targeting, and also obstacles that have yet to be overcome are discussed.
Author: Gary D. Housley Publisher: ISBN: 9783805574587 Category : Audiology Languages : en Pages : 0
Book Description
This special issue represents the third of three issues containing papers arising from the 'Auditory Function and Dysfunction: Molecular and Physiological Mechanisms' symposium held in Auckland, New Zealand in August 2001. It reflects on the exciting advances that are being made in our understanding of the molecular basis of cochlear development, neurodegeneration and the attempts to provide otoprotective strategies. One group of papers deals with some of the genetic aspects of cochlear development and hearing loss. In a second group the advances being made in strategies to protect the inner ear from stress and ototoxic drugs that may ultimately form the basis of treatments for inner ear disorders are being discussed. The last group of papers considers the delivery of compounds to the inner ear for its genetic or pharmacological manipulation. This and the other two issues stemming from the symposium will be valuable contributions to the communication between the wide-ranging disciplines within the hearing sciences and the clinic.
Author: Raymond Romand Publisher: Academic Press ISBN: 0124081088 Category : Science Languages : en Pages : 563
Book Description
Development of Auditory and Vestibular Systems fourth edition presents a global and synthetic view of the main aspects of the development of the stato-acoustic system. Unique to this volume is the joint discussion of two sensory systems that, although close at the embryological stage, present divergences during development and later reveal conspicuous functional differences at the adult stage. This work covers the development of auditory receptors up to the central auditory system from several animal models, including humans. Coverage of the vestibular system, spanning amphibians to effects of altered gravity during development in different species, offers examples of the diversity and complexity of life at all levels, from genes through anatomical form and function to, ultimately, behavior. The new edition of Development of Auditory and Vestibular Systems will continue to be an indispensable resource for beginning scientists in this area and experienced researchers alike. - Full-color figures illustrate the development of the stato-acoustic system pathway - Covers a broad range of species, from drosophila to humans, demonstrating the diversity of morphological development despite similarities in molecular processes involved at the cellular level - Discusses a variety of approaches, from genetic-molecular biology to psychophysics, enabling the investigation of ontogenesis and functional development
Author: Oriana Awwad Publisher: Frontiers Media SA ISBN: 2832550428 Category : Science Languages : en Pages : 148
Book Description
Personalized medicine (precision medicine) is an evolving field that comprises medical interventions tailored to individuals or groups of patients. It is designed to facilitate enhanced screening and earlier disease detection, more precise disease diagnosis, and improved treatment. Personalized medicine allows patients to receive specific therapies that work best for them aiming for more effective treatment, better outcomes, safer clinical managements and more efficient health systems.
Author: Patrick J. Willems Publisher: CRC Press ISBN: 0824756886 Category : Medical Languages : en Pages : 453
Book Description
Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment. Thanks in large part to positional cloning techniques, scientists have identified nearly 100 gene loci implicated in hearing loss since 1995-an extraordinarily rapid rate of gene identification. Genetic Hearing Loss branches into syndromic and nonsyndromic categorical directions in its coverage of the genetics behind hearing loss. Authored by 60 internationally recognized researchers, the book describes the normal development of the ear, updates the classification and epidemiology of hearing loss, and surveys the usage of audiometric tests and diagnostic medical examinations.
Author: Anil K Lalwani Publisher: JP Medical Ltd ISBN: 9351529401 Category : Medical Languages : en Pages : 334
Book Description
The third volume of Recent Advances in Otolaryngology brings clinicians and trainees fully up to date with the latest developments in the rapidly changing field of otolaryngology. Nineteen chapters present new concepts, surgical advances and imaging modalities in each of the subspecialties of otolaryngology. Each chapter begins with a brief summary of the topic, followed by all the recent advances and comprehensive references. A complete chapter is dedicated to geriatric otolaryngology, an emerging subspecialty. Written by an internationally-recognised author and editor team from the US and Europe, this comprehensive manual includes more than 270 images, illustrations and tables. The annual publication cycle of this series ensures the content is current, topical and highly relevant to clinicians and trainees. Key points New volume bringing clinicians up to date with recent advances in otolaryngology Covers all subspecialties of otolaryngology Experienced author and editor team from the US and Europe Includes more than 270 images, illustrations and tables Annual publication cycle ensures current and topical content
Author: S.K.W. Lloyd Publisher: Karger Medical and Scientific Publishers ISBN: 3318063150 Category : Medical Languages : en Pages : 168
Book Description
The development of new technology in hearing aid devices as well as imaging techniques has improved the possibilities of meeting the patient's individual needs. This book, in which experts from around the world have contributed, comprehensively covers advances in all aspects of hearing implantation otology. Chapters review the evidence behind the current applications of the wide range of hearing implants available for different types of hearing loss. Further articles discuss the extended applications of implantation otology and let us have a glimpse into the future of hearing rehabilitation. New imaging techniques for the middle and inner ear are explored as well as innovations to improve Eustachian tube function. The publication is essential reading to otolaryngologists, audiologists and hearing rehabilitation professionals. It provides comprehensive coverage of state of the art hearing rehabilitation across the spectrum of hearing loss: as such it is a perfect tool for those who wish to develop their knowledge within the field.
Author: Helga V. Toriello Publisher: Oxford University Press ISBN: 0199313881 Category : Medical Languages : en Pages : 749
Book Description
This is the third edition of the foremost medical reference on hereditary hearing loss. Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular diagnosis and on genetic susceptibility to ototoxic factors have been added. As in previous editions, the syndromes are grouped by system (visual, metabolic, cardiologic, neurologic, musculoskeletal, endocrine, etc.), with each chapter written by a recognized expert in the field. Written for practicing clinicians, this volume is an excellent reference for physicians, audiologists, and other professionals working with individuals with hearing loss and their families, and can also serve as a text for clinical training programs and for researchers in the hearing sciences.
Author: DR. HAKIM. SABOOWALA
Author: DR. HAKIM. SABOOWALA
Author: Allen F. Ryan
Author: Gary D. Housley
Author: Raymond Romand
Author: Oriana Awwad
Author: Patrick J. Willems
Author: Zuhong He
Author: Anil K Lalwani
Author: S.K.W. Lloyd
Author: Helga V. Toriello