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Author: Mohamed Ibrahim Publisher: CRC Press ISBN: 1000082709 Category : Technology & Engineering Languages : en Pages : 345
Book Description
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Author: Mohamed Ibrahim Publisher: CRC Press ISBN: 1000082709 Category : Technology & Engineering Languages : en Pages : 345
Book Description
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Author: Giuseppe Notarstefano Publisher: ISBN: 9781680836189 Category : Technology & Engineering Languages : en Pages : 148
Book Description
In an increasingly connected world, the term cyber-physical networks has been coined to refer to the communication among devices that is turning smart devices into smart (cooperating) systems. The distinctive feature of such systems is that significant advantage can be obtained if its interconnected, complex nature is exploited. Several challenges arising in cyber-physical networks can be stated as optimization problems. Examples are estimation, decision, learning and control applications. In cyber-physical networks, the goal is to design algorithms, based on the exchange of information among the processors, that take advantage of the aggregated computational power. Distributed Optimization for Smart Cyber-Physical Networks provides a comprehensive overview of the most common approaches used to design distributed optimization algorithms, together with the theoretical analysis of the main schemes in their basic version. It identifies and formalizes classes of problem set-ups that arise in motivating application scenarios. For each set-up, in order to give the main tools for analysis, tailored distributed algorithms in simplified cases are reviewed. Extensions and generalizations of the basic schemes are also discussed at the end of each chapter. Distributed Optimization for Smart Cyber-Physical Networks provides the reader with an accessible overview of the current research and gives important pointers towards new developments. It is an excellent starting point for research and students unfamiliar with the topic.
Author: Krishnendu Chakrabarty Publisher: CRC Press ISBN: 1420008307 Category : Technology & Engineering Languages : en Pages : 228
Book Description
Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.
Author: Tullio Tolio Publisher: Springer ISBN: 3319943588 Category : Technology & Engineering Languages : en Pages : 490
Book Description
This book is open access under a CC BY 4.0 license.This book presents results relevant in the manufacturing research field, that are mainly aimed at closing the gap between the academic investigation and the industrial application, in collaboration with manufacturing companies. Several hardware and software prototypes represent the key outcome of the scientific contributions that can be grouped into five main areas, representing different perspectives of the factory domain:1) Evolutionary and reconfigurable factories to cope with dynamic production contexts characterized by evolving demand and technologies, products and processes.2) Factories for sustainable production, asking for energy efficiency, low environmental impact products and processes, new de-production logics, sustainable logistics.3) Factories for the People who need new kinds of interactions between production processes, machines, and human beings to offer a more comfortable and stimulating working environment.4) Factories for customized products that will be more and more tailored to the final user’s needs and sold at cost-effective prices.5) High performance factories to yield the due production while minimizing the inefficiencies caused by failures, management problems, maintenance.This books is primarily targeted to academic researchers and industrial practitioners in the manufacturing domain.
Author: Jing Cheng Publisher: CRC Press ISBN: 0203305043 Category : Science Languages : en Pages : 453
Book Description
Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.
Author: Shubham Kumar Publisher: CRC Press ISBN: 1000396401 Category : Technology & Engineering Languages : en Pages : 353
Book Description
This book covers theoretical and practical aspects of all major steps in the fabrication sequence. This book can be used conveniently in a semester length course on integrated circuit fabrication. This text can also serve as a reference for practicing engineer and scientist in the semiconductor industry. IC Fabrication are ever demanding of technology in rapidly growing industry growth opportunities are numerous. A recent survey shows that integrated circuit currently outnumber humans in UK, USA, India and China. The spectacular advances in the development and application of integrated circuit technology have led to the emergence of microelectronic process engineering as an independent discipline. Integrated circuit fabrication text books typically divide the fabrication sequence into a number of unit processes that are repeated to form the integrated circuit. The effect is to give the book an analysis flavor: a number of loosely related topics each with its own background material. Note: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.
Author: Mihail C. Roco Publisher: Springer Science & Business Media ISBN: 9401703590 Category : Technology & Engineering Languages : en Pages : 477
Book Description
M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.
Author: Siddharth Goyal Publisher: CRC Press ISBN: 100040109X Category : Computers Languages : en Pages : 270
Book Description
This book focuses primarily on both technical and business aspects needed to select, design, develop and deploy control application (or product) successfully for multiple components in building systems. Designing and deploying a control application require multiple steps such as sensing, system dynamics modelling, algorithms, and testing. This may involve choosing an appropriate methodology and technique at multiple stages during the development process. Understanding the pros and cons of such techniques, most importantly being aware of practically possible approaches in the entire ecosystem, is critical in choosing the best framework and system application for different parts of building systems. Providing a wide overview of the state-of art in controls and building systems, providing guidance on developing an end-to-end system in relation to business fundamentals (distribution channels, stakeholders, marketing, supply-chain and financial management), the book is ideal for fourth-year control/mechanical/electrical engineering undergraduates, graduate students, and practitioners including business leaders concerned with smart building technology.
Author: Fan-Gang Tseng Publisher: MDPI ISBN: 3038421464 Category : Computers Languages : en Pages : 167
Book Description
This book is a printed edition of the Special Issue "Micro/Nanofluidic Devices for Single Cell Analysis" that was published in Micromachines
Author: Bhupinder Singh Publisher: CRC Press ISBN: 135113888X Category : Science Languages : en Pages : 420
Book Description
The objective of this book is to provide the fundamental comprehension of a broad range of topics in an integrated volume such that readership hailing from diverse disciplines can rapidly acquire the necessary background for applying it in pertinent research and development field.
Author: Mohamed Ibrahim
Author: Mohamed Ibrahim
Author: Giuseppe Notarstefano
Author: Krishnendu Chakrabarty
Author: Tullio Tolio
Author: Jing Cheng
Author: Shubham Kumar
Author: Mihail C. Roco
Author: Siddharth Goyal
Author: Fan-Gang Tseng
Author: Bhupinder Singh