Optimal Phased Array Pattern Synthesis for Non-invasive Cancer Ablation of Liver Tumors Using High Intensity Focused Ultrasound PDF Download

Author: Youssry Y. Botros
Publisher:
ISBN:
Category :
Languages : en
Pages : 582

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Author:
Publisher: ScholarlyEditions
ISBN: 1481629816
Category : Medical
Languages : en
Pages : 27

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Book Description
Advances in High-Intensity Focused Ultrasound Ablation Research and Application / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about High-Intensity Focused Ultrasound Ablat in a compact format. The editors have built Advances in High-Intensity Focused Ultrasound Ablation Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about High-Intensity Focused Ultrasound Ablat in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in High-Intensity Focused Ultrasound Ablation Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author: Emad S. Ebbini
Publisher: American Inst. of Physics
ISBN: 9780735406506
Category : Medical
Languages : en
Pages : 482

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Book Description
The proceedings offer a comprehensive view of the state-of-the-art of Therapeutic Ultrasound from the basic science to device technology to clinical practice. Papers describing new therapies of cancer and other tissue abnormalities using innovative device concepts are included. In particular, advanced transducer technologies for noninvasive or minimally invasive delivery of therapeutic ultrasound under image guidance are described by a significant number of papers within the proceedings. The proceedings also include papers on the use of ultrasound in enhancing drug delivery with and without the use of ultrasound contrast agents. In addition, standards and quality assurance issues are addressed by a number of papers. Finally, clinical and pre-clinical in vivo studies are also described.

Author:
Publisher: ScholarlyEditions
ISBN: 1464956936
Category : Medical
Languages : en
Pages : 22

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Book Description
Advances in High-Intensity Focused Ultrasound Ablation Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about High-Intensity Focused Ultrasound Ablation in a compact format. The editors have built Advances in High-Intensity Focused Ultrasound Ablation Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about High-Intensity Focused Ultrasound Ablation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in High-Intensity Focused Ultrasound Ablation Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 892

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Author: Alan Jeffrey Fenn
Publisher: Artech House
ISBN: 1596933801
Category : Medical
Languages : en
Pages : 241

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Book Description
From electromagnetic field theory for tissue heating... to simulations of adaptive phased array thermotherapy for deep tumors of the torso... to coverage of arrays for tumors in the head, neck, breast, and chest wall, this timely resource offers you expert guidance in this emerging area.

Author: Nicholas Pieter Kennedy Ellens
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: Ping Liang
Publisher: Springer
ISBN: 9401793158
Category : Medical
Languages : en
Pages : 333

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Book Description
Microwave ablation is a simple, affordable, and highly precise technique. After its successful application in treating liver tumors, it is now widely used to combat renal tumors, adrenal tumors, thyroid nodes, uterine fibroids and other solid tumors. This book presents 40 successful cases of treating these diseases. A series of picture before treatment, after treatment and from different angles is provided for each kind of tumor treatment. In each chapter, step by step operative techniques and illustrations are included. This book also examines CT, NMR and ultrasonography to evaluate the effect of microwave ablation. Editor Ping Liang, is the Director and Professor at Dept. of Interventional Ultrasound, General Hospital of PLA, Beijing, China. Editor Xiaoling Yu is Professor and Chief physician, Editor Jie Yu is Associate Chief physician at the same department.

Author: Daniel Mcmahon
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Administration of High Intensity Focused Ultrasound (HIFU) treat to tumors in organs shadowedby the ribs is challenging because the ribs absorb ultrasound beams energy causing thetemperature of the ribs to rise, while also distorting the beams, and limiting the focal heatdeposition. As a result, the ribs necessitate the continued development of novel focusingalgorithms that seek to address the difficulties that they present. In this paper, a new approachthat iteratively removes transducer elements is introduced. The method builds on the LimitedPower Deposition (LPD) method, which utilized Semidefinite Relaxation (SDR) as a means ofrelaxing otherwise nonconvex constraints into convex form. The method discussed in this paperiteratively induces sparsity using the one-norm squared as a convex surrogate for the zero-norm.A 1-MHz spherical phased-array is focused onto a target in an inhomogeneous medium insimulations to test the algorithms efficacy. The results of focusing the array with the suggestedalgorithm are compared to the ray tracing (shadowing) approach. The movement of the waves asthey traveled from the array towards the target was modeled using a finite difference timedomain propagation model. Temperature simulations that utilized the inhomogeneous BioheatTransfer Equation (BHTE) were used to determine the temperature rise profile within the Regionof Interest (ROI). These simulation results illustrate the benefits of the optimization basedapproach proposed in this paper over other sparse methods, such as the shadowing method.Accordingly, it is possible to retain the advantages that accompany sparse algorithms, like theshadowing method, without having as large of an impact on focal power deposition. Forexample, the shutoff transducers could be used for other purposes, such as motion tracking andsubsequent refocusing. Due to the ribs influence on the ultrasound beam, the focal powerdeposition is lessened, and as a result, treatment times are increased. Due to the increasedduration of treatment, considering the ROI to be static may lessen treatment efficacy. Thus,motion tracking would allow treatments of organs, such as the liver, that are both obscured bythe ribs and constantly moving to be more effective. Alternatively, in situations where powerconservation is essential, like field treatment administration, then elimination of transducers canact as a means of eliminating unnecessary power consumption.

Author: Tyler R. Fosnight
Publisher:
ISBN:
Category :
Languages : en
Pages : 91

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Echo decorrelation imaging, a pulse-echo method that maps heat-induced changes in ultrasound echoes, was investigated for in vivo monitoring of thermal ablation in a liver cancer model. In open surgical procedures, rabbit liver with implanted VX2 tumor were imaged by image-ablate arrays and treated with bulk ultrasound (unfocused) ablation (N=10) or high-intensity focused ultrasound (HIFU) (N=13). Echo decorrelation and integrated backscatter (IBS) images were formed from pulse-echo images recorded during rest periods following each sonication pulse. Echo decorrelation images were corrected for motion- and noise-induced artifacts using measured echo decorrelation from corresponding sham trials. Sectioned ablated tissue was vitally stained with triphenyl tetrazolium chloride (TTC) and binary images were constructed based on local TTC staining. Analysis was performed for the focused exposures, unfocused exposures and for all exposures combined. Motion correction significantly reduced echo decorrelation in non-ablated liver regions. The reduction was significant in non-ablated VX2 tumor regions for focused exposures and all exposures combined. The reduction was not significant in ablated VX2 tumor regions for unfocused exposures. Echo decorrelation reduction was marginally significant in ablated regions for focused and unfocused exposures and was significant for all exposures combined. Prediction of ablation by echo decorrelation and IBS imaging was assessed using receiver operating characteristic (ROC) curves. Areas under the ROC curve (AUC) were significantly greater than chance for ablated liver prediction by corrected echo decorrelation and IBS. Echo decorrelation did not predict ablated VX2 tumor significantly better than chance for focused exposures. IBS did not predict ablated VX2 tumor better than chance for focused exposures and unfocused exposures. Corrected echo decorrelation predicted ablated liver significantly better than IBS for the focused exposures and all exposures combined. AUC differences between corrected echo decorrelation and IBS were not significant for all exposure groups in ablated VX2 tumor, for which echo decorrelation was marginally higher. At the optimal threshold, defined as the threshold corresponding to the point nearest to the top left-hand corner of the ROC plot, echo decorrelation had a better sensitivity than specificity for the focused and unfocused exposures in normal liver and VX2 tumor. To assess tissue motion effects due to large inter-frame times, echo decorrelation and IBS was computed for inter-frame times up to 847.5 ms. Uncorrected and corrected echo decorrelation prediction performance was marginally affected by large inter-frame times; however, corrected decorrelation was less affected. IBS prediction performance was nearly constant by comparison for large inter-frame times. Over the range of inter-frame times investigated, IBS predicted overall better than echo decorrelation for the unfocused group while echo decorrelation predicted overall better than IBS for the focused group. These results indicate echo decorrelation imaging is a successful predictor of local ablation, with potential for successful clinical implementation.