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One-Locus and Multi-Locus Theory and Recombination

One-Locus and Multi-Locus Theory and Recombination PDF Author: Igor M. Rouzine
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110608197
Category : Mathematics
Languages : en
Pages : 207

Book Description
The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.

One-Locus and Multi-Locus Theory and Recombination

One-Locus and Multi-Locus Theory and Recombination PDF Author: Igor M. Rouzine
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110608197
Category : Mathematics
Languages : en
Pages : 207

Book Description
The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.

Mathematical Modeling of Evolution

Mathematical Modeling of Evolution PDF Author: Igor M. Rouzine
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110615452
Category : Mathematics
Languages : en
Pages : 181

Book Description
The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.

Population Genetics of Multiple Loci

Population Genetics of Multiple Loci PDF Author: Freddy B. Christiansen
Publisher:
ISBN:
Category : Mathematics
Languages : en
Pages : 392

Book Description
Population Genetics of Multiple Loci F. B. Christiansen University of Aarhus, Denmark "This is a very beautiful and powerful study of an area that Christiansen has dominated for many years." - Marcus Feldman, Stanford University, USA Population genetics thrives on the constant interaction between theoretical and empirical knowledge. In the first instance, population genetics was developed using one-locus, two-allele models for genetic variation. The simplicity of these models opened up theoretical developments in population and evolutionary genetics to biologists without specialist training in mathematics. Population genetics of multi-allelic loci is more complex and requires more mathematical insight, and its study is predominantly undertaken by mathematical biologists. Traditional formulations of multi-locus theory do not simplify by assuming two alleles per locus. In this elegant presentation the author provides a formulation of multi-locus population genetics that retains the simplicity of two-allele models. * Provides an accessible and natural extension of classical population genetics to multiple loci * Exposes the population genetic aspects of sexual reproduction * Describes the complexity of evolutionary interactions among genes * Provides the background for insight into the functioning of genetic algorithms applied in computer science * Written by a world leader in the field The book is divided into two main sections. Part I - Recombination and Segregation - includes coverage of random mating, inbreeding, migration and mixing. Part II - Selection - covers numerous phenomena involving natural selection including viability, fertility, mutation and migration. The author has successfully presented the theory in a way that is intelligible to anyone with a reasonably good background in basic mathematics and is devoted to learning multiple loci population genetics. The text is primarily aimed at advanced undergraduate and postgraduate students and researchers interested in genetics and population biology. It is also essential reading for those working or researching in biomathematics and adaptive computing.

Evolutionary Genetics

Evolutionary Genetics PDF Author: R. S. Singh
Publisher: Cambridge University Press
ISBN: 9780521571234
Category : Medical
Languages : en
Pages : 738

Book Description
This book brings out the central role of evolutionary genetics in all aspects of its connection to evolutionary biology.

Rapidly Evolving Genes and Genetic Systems

Rapidly Evolving Genes and Genetic Systems PDF Author: Rama S. Singh
Publisher: Oxford University Press
ISBN: 0199642273
Category : Science
Languages : en
Pages : 309

Book Description
A range of theories on the rates of evolution-from static to gradual to punctuated to quantum-have been developed, mostly by comparing morphological changes over geological timescales as described in the fossil record.

Genetics for Surgeons

Genetics for Surgeons PDF Author: Patrick John Morrison
Publisher: Remedica
ISBN: 1901346692
Category : Medical
Languages : en
Pages : 237

Book Description
Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).

Recombination Variability and Evolution

Recombination Variability and Evolution PDF Author: A.B. Korol
Publisher: Springer Science & Business Media
ISBN: 9780412494109
Category : Science
Languages : en
Pages : 384

Book Description
Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in the fields of evloutionary genetics of recombination, the analysis of genetic markers and breeding applications. The authors analyse recombination through a consideration of computer models, large Drosophila populations and an empirical approach to current theories. Practically-orientated readers will be interested in the discussion of a wide spectrum of mapping methods and the new algorithms proposed for genetic mapping of quantitative loci.

Development of Microbial Ecological Theory: Stability, Plasticity, and Evolution of Microbial Ecosystems

Development of Microbial Ecological Theory: Stability, Plasticity, and Evolution of Microbial Ecosystems PDF Author: Shin Haruta
Publisher: Frontiers Media SA
ISBN: 2889451690
Category :
Languages : en
Pages : 158

Book Description
“How can we develop microbial ecological theory?” The development of microbial ecological theory has a long way to reach its goal. Advances in microbial ecological techniques provide novel insights into microbial ecosystems. Articles in this book are challenging to determine the central and general tenets of the ecological theory that describes the features of microbial ecosystems. Their achievements expand the frontiers of current microbial ecology and propose the next step. Assemblage of these diverse articles hopefully helps to go on this long journey with many avenues for advancement of microbial ecology.

Introduction to Bioinformatics

Introduction to Bioinformatics PDF Author: Stephen A. Krawetz
Publisher: Springer Science & Business Media
ISBN: 9781588290649
Category : Computers
Languages : en
Pages : 776

Book Description
CD-ROM contains: chapter illustrations -- full and trial versions of programs.

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

Book Description