OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage PDF Download
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Author: OECD Publisher: OECD Publishing ISBN: 9264488804 Category : Languages : en Pages : 32
Book Description
The in vitro macromolecular test method is a biochemical in vitro test method that can be used to identify chemicals (substances and mixtures) that have the potential to induce serious eye damage as well as chemicals not requiring classification for eye irritation or serious eye damage.
Author: OECD Publisher: OECD Publishing ISBN: 9264488804 Category : Languages : en Pages : 32
Book Description
The in vitro macromolecular test method is a biochemical in vitro test method that can be used to identify chemicals (substances and mixtures) that have the potential to induce serious eye damage as well as chemicals not requiring classification for eye irritation or serious eye damage.
Author: OECD Publisher: OECD Publishing ISBN: 9264542027 Category : Languages : en Pages : 35
Book Description
This Test Guideline describes an in vitro procedure the identification on its own of chemicals (substances and mixtures) not requiring classification (No Cat), requiring classification for eye irritation (Cat 2) and requiring classification for serious eye damage (Cat 1) according to the UN GHS ocular hazard categories. It makes use of reconstructed human cornea-like epithelium (RhCE) which closely mimics the histological, morphological, biochemical and physiological properties of the human corneal epithelium.
Author: OECD Publisher: OECD Publishing ISBN: 926465609X Category : Languages : en Pages : 30
Book Description
This Test Guideline proposes defined approaches (DA) combining data generated in vitro methods, with information sources such as physicochemical properties.
Author: OECD Publisher: OECD Publishing ISBN: 926418533X Category : Languages : en Pages : 13
Book Description
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Author: OECD Publisher: OECD Publishing ISBN: 9264242244 Category : Languages : en Pages : 25
Book Description
This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.
Author: OECD Publisher: OECD Publishing ISBN: 9264071202 Category : Languages : en Pages : 18
Book Description
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Author: OECD Publisher: OECD Publishing ISBN: 9264070605 Category : Languages : en Pages : 20
Book Description
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Author: OECD Publisher: OECD Publishing ISBN: 9264265295 Category : Languages : en Pages : 74
Book Description
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology of Stably Transfected Transactivation to detect Estrogen Receptor Agonists and Antagonists (ER TA assays).
Author: Frank Dreher Publisher: CRC Press ISBN: 1000590623 Category : Medical Languages : en Pages : 997
Book Description
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice
Author: OECD
Author: OECD
Author: OECD
Author: OECD
Author: OECD
Author: Organisation for Economic Co-operation and Development
Author: OECD
Author: OECD
Author: OECD
Author: OECD
Author: Frank Dreher