OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 492: Reconstructed human Cornea-like Epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage PDF Download

Author: OECD
Publisher: OECD Publishing
ISBN: 9264242546
Category :
Languages : en
Pages : 40

View

Book Description
This Test Guideline describes an in vitro procedure allowing the identification of chemicals (substances and mixtures) not requiring classification and labelling for eye irritation or serious eye damage in accordance with UN GHS.

Author: OECD
Publisher: OECD Publishing
ISBN: 926465609X
Category :
Languages : en
Pages : 30

View

Book Description
This Test Guideline proposes defined approaches (DA) combining data generated in vitro methods, with information sources such as physicochemical properties.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264203869
Category :
Languages : en
Pages : 28

View

Book Description
The Isolated Chicken Eye Test (ICE) Method is an in vitro test method that can be used to identify chemicals (substances or mixtures) as either 1) causing “serious eye damage” (category 1 of the Globally Harmonised System for the Classification and ...

Author: OECD
Publisher: OECD Publishing
ISBN: 926418533X
Category :
Languages : en
Pages : 13

View

Book Description
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...

Author: Organisation for Economic Co-operation and Development
Publisher: Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN: 9789264122215
Category : Chemical industry
Languages : en
Pages :

View

Book Description

Author: Laura Robinson
Publisher: John Wiley & Sons
ISBN: 1118882024
Category : Science
Languages : en
Pages : 402

View

Book Description
Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264070605
Category :
Languages : en
Pages : 20

View

Book Description
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264242244
Category :
Languages : en
Pages : 25

View

Book Description
This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264071202
Category :
Languages : en
Pages : 18

View

Book Description
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

Author: Nattaya Lourith
Publisher: CRC Press
ISBN: 1000410323
Category : Medical
Languages : en
Pages : 170

View

Book Description
This concise guide to cosmetic active ingredients derived from plant sources will bring scientists, researchers in cosmetic science, and dermatology practitioners up to speed with the basic science and its applications in manufacturing and dermatological practice. It acts as a concise and quick reference from key researchers and an up-to-date guide to translation into practice, providing an easy-to-consult resource on a topic of great current interest.