OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties PDF Download

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264067418
Category :
Languages : en
Pages : 21

Book Description
The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264067418
Category :
Languages : en
Pages : 21

Book Description
The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 441: Hershberger Bioassay in Rats A Short-term Screening Assay for (Anti)Androgenic Properties

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 441: Hershberger Bioassay in Rats A Short-term Screening Assay for (Anti)Androgenic Properties PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264076336
Category :
Languages : en
Pages : 20

Book Description
The Hershberger Bioassay is an in vivo short–term screening test. It evaluates the ability of a chemical to elicit biological activities consistent with androgen agonists, antagonists or 5 á-reductase inhibitors. The current bioassay is based on the ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264122648
Category :
Languages : en
Pages : 27

Book Description
This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264185372
Category :
Languages : en
Pages : 25

Book Description
This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070680
Category :
Languages : en
Pages : 13

Book Description
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078851
Category :
Languages : en
Pages : 217

Book Description
This detailed background review paper provides a summary of the relevant literature (up to September 2001) relevant to the standardisation and validation of the rodent uterotrophic bioassay.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070729
Category :
Languages : en
Pages : 9

Book Description
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071024
Category :
Languages : en
Pages : 15

Book Description
This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078851
Category :
Languages : en
Pages : 218

Book Description
This detailed background review paper provides a summary of the relevant literature (up to September 2001) relevant to the standardisation and validation of the rodent uterotrophic bioassay. The rodent uterotrophic bioassay is being validated as part of the OECD Test Guidelines Programme. The rodent uterotrophic bioassay is based on the principle that the uterus is under the control of oestrogens to stimulate and maintain growth. If endogenous sources of this hormone are not available, the animal will require an exogenous source to initiate and/or restore uterine growth.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264076220
Category :
Languages : en
Pages : 38

Book Description
This Test Guideline describes an in vivo screening assay for certain endocrine active substances where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days ...
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