OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070842
Category :
Languages : en
Pages : 8

Book Description
This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...

Test No. 443: Extended One-Generation Reproductive Toxicity Study

Test No. 443: Extended One-Generation Reproductive Toxicity Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264122559
Category :
Languages : en
Pages : 25

Book Description
This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070869
Category :
Languages : en
Pages : 13

Book Description
This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ...

Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070982
Category :
Languages : en
Pages : 14

Book Description
The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks; females should be dosed throughout the study (approximately 54 days). Normally, matings “one male to one ...

Test No. 421: Reproduction/Developmental Toxicity Screening Test

Test No. 421: Reproduction/Developmental Toxicity Screening Test PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070966
Category :
Languages : en
Pages : 10

Book Description
The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070826
Category :
Languages : en
Pages : 14

Book Description
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071202
Category :
Languages : en
Pages : 18

Book Description
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 412: Subacute Inhalation Toxicity: 28-Day Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 412: Subacute Inhalation Toxicity: 28-Day Study PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070788
Category :
Languages : en
Pages : 23

Book Description
This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070605
Category :
Languages : en
Pages : 20

Book Description
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT)

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT) PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264242252
Category :
Languages : en
Pages : 53

Book Description
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...