Test No. 211: Daphnia magna Reproduction Test PDF Download

Author: OECD
Publisher: OECD Publishing
ISBN: 9264070125
Category :
Languages : en
Pages : 23

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Book Description
The test method described in this Test Guideline assesses the effect of chemicals on the reproductive output of Daphnia magna Straus. To this end, young female Daphnia are exposed to the test substance added to water at a range of concentrations (at ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264069941
Category :
Languages : en
Pages : 12

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Book Description
This Test Guideline describes an acute toxicity test to assess effects of chemicals towards daphnids (usually Daphnia magna Staus). Young daphnids, aged less than 24 hours at the start of the test, are exposed to the test substance at a range of ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264070265
Category :
Languages : en
Pages : 29

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Book Description
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264203788
Category :
Languages : en
Pages : 24

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Book Description
The test method described in this Test Guideline, is intended to define the lethal and sub-lethal effects of chemicals on the early life stages of the species tested. The early-life stages of fish are exposed to five concentrations of the test ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264070281
Category :
Languages : en
Pages : 28

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Book Description
This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264264477
Category :
Languages : en
Pages : 24

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Book Description
This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264185291
Category :
Languages : en
Pages : 72

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Book Description
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264017984
Category :
Languages : en
Pages : 244

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Book Description
The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.

Author: Despo Fatta-Kassinos
Publisher: Springer Science & Business Media
ISBN: 9048135095
Category : Technology & Engineering
Languages : en
Pages : 505

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Book Description
The history of chemistry and pharmaceutical sciences is an impressive success story. The products of chemical and pharmaceutical industries are present eve- where in our everyday life. They help to pursue the modern way of living and they contribute to our high standard of living and safety, mobility, communication te- nologies, food, health, textiles and drinking water treatment, among many others. These products are labeled under the categories: pharmaceuticals, pesticides, det- gents, fertilizers, dyes, paints, preservatives, food additives and personal care pr- ucts, to name a few. Within these categories, groups of chemicals with similar structures can be found. However, often groups of chemicals with very different structures belong to the same category. For a long time the production of chemicals and pharmaceuticals, their usage and application was connected with the heavy pollution of the environment and serious health effects. At the end of the last century, it was realised that the products of che- cal and pharmaceutical industries are presenting a new type of environmental pol- tion that may also pose a health risk to the consumer. Most chemicals are used in so-called open applications in excessive amounts e. g. for personal care, hygiene, plant protection, health and in textiles. In many cases such as scents, detergents, textile chemicals, surface disinfectants, pesticides and others it is unavoidable that these chemicals are released into the environment according to their intended use.

Author: Saravana Babu Chidambaram
Publisher: Springer Nature
ISBN: 9811660921
Category : Medical
Languages : en
Pages : 205

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Book Description
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.