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OECD Guidelines for Testing of Chemicals

OECD Guidelines for Testing of Chemicals PDF Author: Organisation for Economic Co-operation and Development
Publisher: Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN: 9789264122215
Category : Chemical industry
Languages : en
Pages :

Book Description

OECD Guidelines for Testing of Chemicals

OECD Guidelines for Testing of Chemicals PDF Author: Organisation for Economic Co-operation and Development
Publisher: Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN: 9789264122215
Category : Chemical industry
Languages : en
Pages :

Book Description

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Specific Target Organ Systemic Toxicity Following Single or Repeated Exposure in OECD Member Countries

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Specific Target Organ Systemic Toxicity Following Single or Repeated Exposure in OECD Member Countries PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078428
Category :
Languages : en
Pages : 20

Book Description
This detailed review document examines member country hazard classification systems for specific target organ systemic toxicity following single or repeated exposure.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals PDF Author: OECD
Publisher: OECD Publishing
ISBN: 926407838X
Category :
Languages : en
Pages : 313

Book Description
This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Revised Analysis of Responses Received from Member Countries to the Questionnaire on Data Requirements for Acute Oral Toxicity

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Revised Analysis of Responses Received from Member Countries to the Questionnaire on Data Requirements for Acute Oral Toxicity PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078436
Category :
Languages : en
Pages : 53

Book Description
This report presents a revised anlaysis of responses received from member countries to the Questionnaire on Data Requirements for Acute Oral Toxicity.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Mixtures

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Mixtures PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078460
Category :
Languages : en
Pages : 178

Book Description
This document focuses on the health and environmental hazards of mixtures.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078487
Category :
Languages : en
Pages : 87

Book Description
This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078495
Category :
Languages : en
Pages : 112

Book Description
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification in OECD Member Countries of Substances and Mixtures which cause Respiratory Tract Irritation and Corrosion

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification in OECD Member Countries of Substances and Mixtures which cause Respiratory Tract Irritation and Corrosion PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264079092
Category :
Languages : en
Pages : 13

Book Description
This detailed review documents examines member country classification of substances and mixtures which cause respiratorytract irritation and corrosion.

EPA 540/9

EPA 540/9 PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 132

Book Description

Principles of Toxicology Testing, Second Edition

Principles of Toxicology Testing, Second Edition PDF Author: Frank A Barile
Publisher: CRC Press
ISBN: 1842145282
Category : Medical
Languages : en
Pages : 368

Book Description
Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.
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