Ocular neurodegenerative diseases: Novel mechanisms, diagnosis, and therapeutic strategies PDF Download

Author: Dan Wen
Publisher: Frontiers Media SA
ISBN: 2832535003
Category : Science
Languages : en
Pages : 187

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Author: Shamim I. Ahmad
Publisher: Springer Science & Business Media
ISBN: 1461406536
Category : Medical
Languages : en
Pages : 421

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Book Description
The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600

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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author: Shaochong Zhang
Publisher: Frontiers Media SA
ISBN: 2832503276
Category : Medical
Languages : en
Pages : 391

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Author: Matthew M. LaVail
Publisher: Springer Science & Business Media
ISBN: 1461406315
Category : Medical
Languages : en
Pages : 867

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This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Author: Jose Hurst
Publisher: Frontiers Media SA
ISBN: 2832520251
Category : Science
Languages : en
Pages : 109

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Book Description
Oxidative stress, free radicals, antioxidants - when it comes to our health, this topic is taking up more and more attention. But what is oxidative stress, how does it arise and what effects does it have on the most sensitive area of our body: the neuronal tissue or the retina. Many neurological diseases affecting the brain or the retina are associated with elevated levels of reactive oxygen species (ROS). High levels of ROS can cause damage to proteins, nucleic acids, lipids, membranes, and organelles such as mitochondria, and can be caused not only by external stimuli but also by aging. Most theories on the aging scenario assume that cumulative oxidative stress leads to mitochondrial changes, mitochondrial dysfunction, and oxidative damage. Therefore, it is not surprising that excess ROS is among others associated with the development of a variety of age-related neuronal diseases, including Alzheimer's and Parkinson's disease, as well as retinal diseases diabetic retinopathy, glaucoma, and age-related macular (AMD) degeneration. The aim of this Research Topic is to answer open questions, to combine already gained knowledge, to close the gaps between ophthalmology and neurology when it comes to oxidative stress in order to understand the underlying pathways and derive innovative therapies. It searches for the updates and new findings in both fields that answer the central question: are the same cell types affected by oxidative stress in the same way in the brain and retina? Experimental studies or patient studies that provide new insights are welcome, as well as studies that investigate antioxidant therapies.

Author: Christine Nguyen
Publisher: Frontiers Media SA
ISBN: 2889712591
Category : Science
Languages : en
Pages : 282

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Author: Helga Kolb
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: Tsuneya Ikezu
Publisher: Springer
ISBN: 3319440225
Category : Medical
Languages : en
Pages : 1045

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Book Description
The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681083396
Category : Science
Languages : en
Pages : 207

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Book Description
Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s disease research.