Author: Thomas Blizard Curling
Publisher:
ISBN:
Category : Anus
Languages : en
Pages : 290
Book Description
Observations on the Diseases of the Rectum
Practical observations on some of the diseases of the rectum, anus, and contiguous textures
Observations of the diseases of the rectum
Author: Thomas Blizard Curling
Publisher:
ISBN:
Category :
Languages : en
Pages : 160
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 160
Book Description
Observations on the principal diseases of the rectum and anus
Observations on the Principal Diseases of the Rectum and Anus ... Second edition, considerably enlarged
Colonic Motility
Author: Sushil K. Sarna
Publisher: Biota Publishing
ISBN: 1615041516
Category : Medical
Languages : en
Pages : 159
Book Description
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Publisher: Biota Publishing
ISBN: 1615041516
Category : Medical
Languages : en
Pages : 159
Book Description
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Asbestos
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309101697
Category : Medical
Languages : en
Pages : 341
Book Description
In conjunction with drafting comprehensive legislation concerning compensation for health effects related to asbestos exposure (the Fairness in Asbestos Injury Act), the Senate Committee on the Judiciary directed the Institute of Medicine to assemble the Committee on Asbestos: Selected Health Effects. This committee was charged with addressing whether asbestos exposure is causally related to adverse health consequences in addition to asbestosis, mesothelioma, and lung cancer. Asbestos: Selected Cancers presents the committee's comprehensive distillation of the peer-reviewed scientific and medical literature regarding association between asbestos and colorectal, laryngeal, esophageal, pharyngeal, and stomach cancers.
Publisher: National Academies Press
ISBN: 0309101697
Category : Medical
Languages : en
Pages : 341
Book Description
In conjunction with drafting comprehensive legislation concerning compensation for health effects related to asbestos exposure (the Fairness in Asbestos Injury Act), the Senate Committee on the Judiciary directed the Institute of Medicine to assemble the Committee on Asbestos: Selected Health Effects. This committee was charged with addressing whether asbestos exposure is causally related to adverse health consequences in addition to asbestosis, mesothelioma, and lung cancer. Asbestos: Selected Cancers presents the committee's comprehensive distillation of the peer-reviewed scientific and medical literature regarding association between asbestos and colorectal, laryngeal, esophageal, pharyngeal, and stomach cancers.
Current Therapy in Colon and Rectal Surgery E-Book
Author: Victor W. Fazio
Publisher: Elsevier Health Sciences
ISBN: 0323296912
Category : Medical
Languages : en
Pages : 539
Book Description
For more than 25 years, Current Therapy in Colon and Rectal Surgery has been the go-to resource for preparing for the American Board of Surgery certification exam. Following in this tradition, the 3rd Edition offers a comprehensive, contemporary summary of treatment options for colorectal diseases, with a focus on practical clinical science and applications. In a single, portable volume, you'll find complete coverage of new diagnostic modalities, medical therapeutics, and surgical treatment options, including minimally invasive surgery. Easy to read and digest, it provides a quick consultation with experts on the essentials of colon and rectal surgery. - Consult this title for a quick overview before you enter the OR, and use it as a review tool for board certification and recertification. - Nearly 100 succinct chapters, just 3 or 4 pages each, written by leading experts in colorectal surgery. - Five chapters devoted exclusively to different aspects of rectal cancer. - Other key topics include minimally invasive surgery, reparative surgery, maturing outcomes, and managing surgical risk. - New chapters focus on hot topics such as intestinal transplants, enhanced recovery programs, and the management of peristomal hernias. - Updated information on the molecular biology of colorectal cancer and its implications for therapy.
Publisher: Elsevier Health Sciences
ISBN: 0323296912
Category : Medical
Languages : en
Pages : 539
Book Description
For more than 25 years, Current Therapy in Colon and Rectal Surgery has been the go-to resource for preparing for the American Board of Surgery certification exam. Following in this tradition, the 3rd Edition offers a comprehensive, contemporary summary of treatment options for colorectal diseases, with a focus on practical clinical science and applications. In a single, portable volume, you'll find complete coverage of new diagnostic modalities, medical therapeutics, and surgical treatment options, including minimally invasive surgery. Easy to read and digest, it provides a quick consultation with experts on the essentials of colon and rectal surgery. - Consult this title for a quick overview before you enter the OR, and use it as a review tool for board certification and recertification. - Nearly 100 succinct chapters, just 3 or 4 pages each, written by leading experts in colorectal surgery. - Five chapters devoted exclusively to different aspects of rectal cancer. - Other key topics include minimally invasive surgery, reparative surgery, maturing outcomes, and managing surgical risk. - New chapters focus on hot topics such as intestinal transplants, enhanced recovery programs, and the management of peristomal hernias. - Updated information on the molecular biology of colorectal cancer and its implications for therapy.
Rectal Cancer Treatment
Author: M.W. Büchler
Publisher: Springer Science & Business Media
ISBN: 3540274499
Category : Medical
Languages : en
Pages : 284
Book Description
Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.
Publisher: Springer Science & Business Media
ISBN: 3540274499
Category : Medical
Languages : en
Pages : 284
Book Description
Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.