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Author: Karsten Weis Publisher: Springer Science & Business Media ISBN: 3540446036 Category : Science Languages : en Pages : 222
Book Description
Bidirectional traffic of macromolecules across the nuclear envelope is an active and essential transport process in all eukaryotic cells. Work on various model systems has led to a tremendous increase in our understanding of nuclear transport in recent years. This volume summarizes our current knowledge of protein and RNA transport into and out of the nucleus. It contains nine up-to-date reviews which cover various aspects of nucleocytoplasmic transport, including the structure and function of the nuclear pore complex, the role of soluble transport factors in protein and RNA transport, and the regulation of protein transport through the nuclear pore.
Author: Karsten Weis Publisher: Springer Science & Business Media ISBN: 3540446036 Category : Science Languages : en Pages : 222
Book Description
Bidirectional traffic of macromolecules across the nuclear envelope is an active and essential transport process in all eukaryotic cells. Work on various model systems has led to a tremendous increase in our understanding of nuclear transport in recent years. This volume summarizes our current knowledge of protein and RNA transport into and out of the nucleus. It contains nine up-to-date reviews which cover various aspects of nucleocytoplasmic transport, including the structure and function of the nuclear pore complex, the role of soluble transport factors in protein and RNA transport, and the regulation of protein transport through the nuclear pore.
Author: Weidong Yang Publisher: Springer ISBN: 3319773097 Category : Science Languages : en Pages : 274
Book Description
Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.
Author: Mohamed Mohamed El-Wakil Publisher: ISBN: Category : Technology & Engineering Languages : en Pages : 520
Book Description
This book covers the processes of energy (heat) generation in nuclear processes, the transport of that energy by the reactor coolant to the power cycle, and the limitations imposed by the transport mechanism on the design of nuclear reactor cores. Homework problems are presented at the end of each chapter.
Author: Carl Feldherr Publisher: Academic Press ISBN: 0323152988 Category : Science Languages : en Pages : 385
Book Description
Nuclear Trafficking is a summary of the state of knowledge in nuclear trafficking, and is organized into five parts. The book begins by discussing the diffusion and signal-mediated transport through the pores. It then looks into the detailed accounts of pore structure and composition, nuclear localization signals, signal binding proteins, RNA efflux, and biochemical factors influencing nucleocytoplasmic exchange. This book will be very useful to those people new to this field of interest.
Author: Ralph H. Kehlenbach Publisher: CRC Press ISBN: Category : Science Languages : en Pages : 222
Book Description
Both from a morphological and a functional point of view, the nucleus is central to modern cell biology. Transport of proteins and RNAs between the nucleus and the cytoplasm continues to be a fascinating research topic on its own. Furthermore, it affects many aspects of gene expression and general cellular functions and has far-reaching implications for human health. In this book, we cover a wide range of topics from the nuclear transport field. Individual chapters deal with the general concepts of nucleocytoplasmic transport, with various transport pathways like nuclear protein import, mRNA export and tRNA trafficking, and with the molecular mechanisms that govern macromolecular exchange between the two compartments. Others address new technologies that will help to answer open questions in the future. Together, we hope to provide a collection of reviews that should be useful for experts in the field, as well as for a wider audience.
Author: National Research Council Publisher: National Academies Press ISBN: 0309164826 Category : Science Languages : en Pages : 355
Book Description
This new report from the National Research Council's Nuclear and Radiation Studies Board (NRSB) and the Transportation Research Board reviews the risks and technical and societal concerns for the transport of spent nuclear fuel and high-level radioactive waste in the United States. Shipments are expected to increase as the U.S. Department of Energy opens a repository for spent fuel and high-level waste at Yucca Mountain, and the commercial nuclear industry considers constructing a facility in Utah for temporary storage of spent fuel from some of its nuclear waste plants. The report concludes that there are no fundamental technical barriers to the safe transport of spent nuclear fuel and high-level radioactive and the radiological risks of transport are well understood and generally low. However, there are a number of challenges that must be addressed before large-quantity shipping programs can be implemented successfully. Among these are managing "social" risks. The report does not provide an examination of the security of shipments against malevolent acts but recommends that such an examination be carried out.
Author: D.G. Walton Publisher: Springer Science & Business Media ISBN: 1475700466 Category : Technology & Engineering Languages : en Pages : 409
Book Description
The transport requirements of the nuclear industry are unique in many respects. Thi s is not because cargoes are particularly large or hazardous by compari son wi th other industries but because standards of performance required in every aspect of the activity are so much greater than those required for any other industry. Transport of nuclear materials is subject to existing statutory regulations applied not only nationally but internationally. In addition to this, users of transport demand the highest standards of performance for their own purposes particularly in the area of quality assurance. Similar considerations also apply to the transport of non-nuclear materials where the transport link often has to tie in with project management and quality assurance requirements. Safety and security of nuclear materials are of paramount importance but even when these aspects are of a completely acceptable standard public attitudes to the transport activities have to be addressed adequately. The transport system itself consists of many components. The route, the vehicles, the containers, and the individual packages. The performance of each component determines the performance of the total system: all these factors were presented in the 1988 Conference on Transportation for the Nuclear Industry, giving a broad over-view of current practice together with wide ranging consideration of future requirements and developments.
Author: Karsten Weis
Author: Karsten Weis
Author: Bruce Alberts
Author: Weidong Yang
Author: Mohamed Mohamed El-Wakil
Author: Carl Feldherr
Author: Karsten Weis
Author: Ralph H. Kehlenbach
Author: National Research Council
Author: D.G. Walton
Author: Reiner Peters