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Author: P. R. Cook Publisher: Wiley-Liss ISBN: Category : Science Languages : en Pages : 376
Book Description
The nucleus guides the life processes of the cell by directing cellular reproduction, differentiation during development, and metabolism. The study of the structure and function of the nucleus along with its genetic material serves as the foundation for the science of genetics. Principles of Nuclear Structure and Function provides a comprehensive overview of the cell nucleus by illustrating the connection between function and the architecture of the nucleus. Richly illustrated throughout, each chapter includes an overview, detailed examples, summary points, references, and callout boxes highlighting methods and cutting-edge technology. The appendix provides a useful list of related Web sites. Some of the subjects reviewed within Principles of Nuclear Structure and Function include: * Nuclear structure, replication, damage, and repair * Regulation of gene expression * The cell cycle * Meiosis and recombination This timely volume presents functional studies within their proper structural context and is an informative profile of the cell and molecular biology in nuclei and chromatin. For those studying cell biology, along with molecular and cell biologists, geneticists, and reproductive biologists, Principles of Nuclear Structure and Function is a definitive resource. Visit www.wiley.com/cook for supplementary information, including additional Web resources, downloadable figures, and discussion questions.
Author: P. R. Cook Publisher: Wiley-Liss ISBN: Category : Science Languages : en Pages : 376
Book Description
The nucleus guides the life processes of the cell by directing cellular reproduction, differentiation during development, and metabolism. The study of the structure and function of the nucleus along with its genetic material serves as the foundation for the science of genetics. Principles of Nuclear Structure and Function provides a comprehensive overview of the cell nucleus by illustrating the connection between function and the architecture of the nucleus. Richly illustrated throughout, each chapter includes an overview, detailed examples, summary points, references, and callout boxes highlighting methods and cutting-edge technology. The appendix provides a useful list of related Web sites. Some of the subjects reviewed within Principles of Nuclear Structure and Function include: * Nuclear structure, replication, damage, and repair * Regulation of gene expression * The cell cycle * Meiosis and recombination This timely volume presents functional studies within their proper structural context and is an informative profile of the cell and molecular biology in nuclei and chromatin. For those studying cell biology, along with molecular and cell biologists, geneticists, and reproductive biologists, Principles of Nuclear Structure and Function is a definitive resource. Visit www.wiley.com/cook for supplementary information, including additional Web resources, downloadable figures, and discussion questions.
Author: Miguel Berrios Publisher: Academic Press ISBN: 0125641559 Category : Medical Languages : en Pages : 659
Book Description
This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols
Author: K Leon Publisher: Elsevier ISBN: 0323148999 Category : Science Languages : en Pages : 476
Book Description
Aspects of Nuclear Structure and Function deals with various aspects of nuclear structure and function and covers topics ranging from the ultrastructure of the female gamete to the structure, biochemistry, and functions of the nuclear envelope. Banding patterns in chromosomes, histones and nonhistone proteins, and the transfer of genetic information in polytene cells are also discussed. This book is comprised of six chapters and begins by presenting a comparative view of some aspects of the ultrastructure of the vegetative (growth) aspects of oogenesis, with emphasis on microtubules, intercellular bridges of differentiating oocytes, and vitellogenesis as well as accessory structures of the egg envelope. The following chapters explore the structure, biochemistry, and functions of the nuclear envelope; banding patterns in chromosomes; chromosomal proteins (histones and nonhistone proteins); transfer of genetic information in polytene cells; and the intracellular biology of DNA polymerases in eukaryotic cells, their association with the nucleus, and how this association changes during the mitotic cell cycle. The relationship between eukaryotic DNA polymerases and DNA replication is also examined. This monograph should be a valuable resource for biochemists.
Author: Ana Pombo Publisher: ISBN: 9781621823896 Category : Cell nuclei Languages : en Pages : 300
Book Description
The nucleus is the most prominent structure in eukaryotic cells. It houses the cell's DNA and is the hub for DNA replication, transcription, and RNA processing. Despite its prominence and importance, our understanding of how the nucleus and its DNA are organized in space and time--and the implications of that organization for proper function--has lagged behind that of other cellular structures. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers recent advances in our understanding of nuclear organization and function. The contributors discuss the 3D organization of chromatin, the various nuclear bodies and compartments that have been identified, and the roles of RNA and actin in shaping nuclear organization, as well as how these structures interact with each other and with peripheral features (e.g., the nuclear pore complex and inner nuclear membrane proteins) to carry out the work of the nucleus. Insights into DNA replication timing and RNA processing dynamics based on new technologies aimed at examining chromatin and other intranuclear structures at high resolution are also included. Multiple chapters are devoted to physiological and disease processes involving disruption of nuclear structure and function (e.g., viral infection). This volume is therefore essential reading for all cell and molecular biologists, as well as pathologists interested in the role of nuclear architecture in disease.
Author: William Hornyak Publisher: Elsevier ISBN: 0323144381 Category : Science Languages : en Pages : 620
Book Description
Nuclear Structure covers material usually discussed in courses about nuclear structure. The presentation, although recommends and not necessarily requires the reader to have some knowledge of introductory nuclear physics at an elementary or undergraduate level, requires a good knowledge of the elements of quantum mechanics, including an introduction to Dirac theory. The text covers topics such as nucleon-nucleon forces, the boson-exchange model, high-energy electron scattering, and the single particle shell model. Also covered are topics such as single-particle potentials, spin-orbit interactions, the individual-particle model, states of different nuclei, electromagnetic interactions with nuclei, and beta-decay. The book is recommended for nuclear physics students who have background knowledge on nuclear structure and would like to know more about the topic.
Author: R. Curtis Bird Publisher: Elsevier ISBN: 0080537812 Category : Science Languages : en Pages : 317
Book Description
Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology.* Mechanisms of interaction between nuclear structure and genes* Gene expression regulation by elements of the nuclear matrix* How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Author: K. Nagata Publisher: Springer Science & Business Media ISBN: 4431301305 Category : Science Languages : en Pages : 285
Book Description
The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.
Author: National Research Council Publisher: National Academies Press ISBN: 0309173663 Category : Science Languages : en Pages : 222
Book Description
Dramatic progress has been made in all branches of physics since the National Research Council's 1986 decadal survey of the field. The Physics in a New Era series explores these advances and looks ahead to future goals. The series includes assessments of the major subfields and reports on several smaller subfields, and preparation has begun on an overview volume on the unity of physics, its relationships to other fields, and its contributions to national needs. Nuclear Physics is the latest volume of the series. The book describes current activity in understanding nuclear structure and symmetries, the behavior of matter at extreme densities, the role of nuclear physics in astrophysics and cosmology, and the instrumentation and facilities used by the field. It makes recommendations on the resources needed for experimental and theoretical advances in the coming decade.
Author: J.R. Harris Publisher: Springer ISBN: 9781461279181 Category : Science Languages : en Pages : 504
Book Description
This collection of 101 short communications, submitted by some of the participants at the 11th Nuclear Workshop held in Suzdal, USSR, 18-23 September, 1989, provides a representative survey of the material presented at the Workshop. Articles have been submitted by both those who delivered lectures and those who had poster presentations. The order of presentation at the Nuclear Workshop is roughly maintained within this proceedings book, but the session titles within the scientific program have not been utilized as discrete subdivisions within the book, because of the considerable overlap of subject matter. The overall sequence is as follows: Genome structure, Gene Structure and Expression, Nucleolar Genes, Structure and Proteins, Chromatin and Nuclear Granules, Nuclear Matrix and Nuclear Proteins, Replication and Transcription and finally Nuclear Envelope and Nuclear Cytoplasmic Transport. Several articles on Nuclear Lipids are also included, stemming from an evening round-table discussion on lipids. The third Wilhelm Bernhard Lecture was delivered in Suzdal by Professor Harris Busch, who can be seen in the photograph above (on the left) in the presence of Professor Ilya B. Zbarsky, President of the organizing committee for the 11th Nuclear Workshop. (Previous Wilhelm Bernhard lecturers have been Ronald H. Reeder, in Krakow, Poland, 1985 and Oscar L. Miller, Jr. , in Stevensbeek, The Netherlands, in 1987).
Author: P. R. Cook
Author: P. R. Cook
Author: Miguel Berrios
Author: K Leon
Author: Ana Pombo
Author: William Hornyak
Author: R. Curtis Bird
Author: K. Nagata
Author: National Research Council
Author: J.R. Harris
Author: Peter Fantes