Author: Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 90
Book Description
NTP GMM.
Author: Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 90
Book Description
Genetically Modified Model Report on Toxicology and Carcinogenesis Study of Glycidol (CAS No. 556-52-5) in Genetically Modified Haploinsufficient P16Ink4a/p19Arf Mice (Gavage Study)
Author: J. K. DunnickPublisher: DIANE Publishing
ISBN: 1437902243
Category :
Languages : en
Pages : 81
Book Description
Glycidol is used as a chemical intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, Glycidol ethers, and amines. Glycidol was nominated for carcinogenecity study by the Environmental Protection Agency (EPA). Glycidol was selected for study in the haploinsufficient p16Ink4a/p19Arf mouse because it was found to be carcinogenic in rats and mice in conventional 2-year rodent studies (NTP, 1990), but was negative in a study in p53+/- mice (Tennant et al., 1999). In this study, male and female mice received Glycidol (greater than 95% pure) by gavage for 40 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.
Deep Learning for Biological Network Analysis
Author: Jianye HaoPublisher: Frontiers Media SA
ISBN: 2889742946
Category : Science
Languages : en
Pages : 123
Book Description
Environmental Health Perspectives
Author: Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 676
Book Description
Alternative Sweeteners
Author: Lyn O'Brien-NaborsPublisher: CRC Press
ISBN: 1439846154
Category : Technology & Engineering
Languages : en
Pages : 567
Book Description
The fourth edition of Alternative Sweeteners follows the same formula as the previous three books by discussing each sweetener in terms of its characteristics. Qualities covered include means of production, physical characteristics, utility, and relative sweetness (compared to sucrose). Technical qualities covered include admixture potential, application, availability, shelf life, transport, metabolism, carcinogenicity, and other toxicity evaluation data. A new chapter on the sweetener Advantame has been added, and new contributors have updated information throughout the book. Also new is a section on how stevia sweeteners have been examined and deemed safe by the Joint FAO/WHO Expert Committee on Food Additives and the US FDA.
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3: Environmental Toxicologic Pathology and Major Toxicant Classes
Author: Wanda M. HaschekPublisher: Elsevier
ISBN: 0443161542
Category : Medical
Languages : en
Pages : 974
Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides updated and revised chapters for in-depth discussions of toxicologic pathology for the protection of the environment and food supplies - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Federal Register
Author: Technical Report Series
Author: Advances in Sulfide Smelting
Author: Hong Yong SohnPublisher: American Society of Civil Engineers
ISBN:
Category : Science
Languages : en
Pages : 424
Book Description
Author: