Novel Methodologies and Applications for Biological Calorimetry PDF Download

Author: Anthony Joseph Fontana
Publisher:
ISBN:
Category :
Languages : en
Pages : 342

View

Book Description

Author: John E. Ladbury
Publisher: John Wiley & Sons
ISBN: 0470011114
Category : Science
Languages : en
Pages : 276

View

Book Description
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability. Calorimeters have now become commonplace in bioscience laboratories. As a result, the number of those proficient in experimentation in this field has risen dramatically, as has the range of experiments to which these methods have been applied. Applications extend from studies in small molecule and solvent biophysics, through drug screening to whole cell assays. The technology has developed to include higher levels of sensitivity (and hence smaller sample size requirements) and a drive towards high-throughput technology, creating a very large user base in both academia and the pharmaceutical industry. This book is a fully revised and updated edition of the successful Biocalorimetry: Applications of Calorimetry in the Biological Sciences, published in 1998. Since then, there have been many advances in the instrumentation as well as in its applications and methodology. There are general chapters highlighting the usage of the isothermal titration calorimeter and the differential scanning calorimeter, more advanced chapters on specific applications and tutorials that cover the idiosyncrasies of experimental methods and data analysis. The book draws these together to create the definitive biological calorimetric text book. This book both explains the background to the method and describes novel, high-impact applications. It features works of interest to the experienced calorimetrist and the enthusiastic dilettante. The book should be of interest to all working in the field of biocalorimetry, from graduate students to researchers in academia and in industry.

Author: John E. Ladbury
Publisher: Wiley
ISBN: 9780471977810
Category : Science
Languages : en
Pages : 0

View

Book Description
Biocalorimetry Applications of Calorimetry in the Biological Sciences Edited by John E. Ladbury, University College London, UK and Babur Z. Chowdhry, University of Greenwich, London, UK Biocalorimetry: Applications of Calorimetry in the Biological Sciences is the first book to bring together an overview of the two key methods in calorimetry, (isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC)), with a wide variety of biological applications, such as DNA-drug/protein interactions, protein-protein (ligand) interactions and protein denaturation studies. Written by a team of international researchers, it discusses the principles and practical application of these methods, including their advantages and disadvantages. This book will be of interest to researchers working in biochemistry, biophysics and molecular biology, particularly those in the pharmaceutical, food and biotechnology industries. In addition, Biocalorimetry: Applications of Calorimetry in the Biological Sciences provides valuable insight for lecturers and students, (particularly final year undergraduates and postgraduates), for teaching purposes, as well as for understanding the theoretical basis and wider practical applications of calorimetry.

Author: A. E. Beezer
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 504

View

Book Description
This book is an up-to-date account of microcalorimetry as applied to biological topics and gives a comprehensive review of this growing area of research. For non- calorimetrists it is intended as an introduction and for those already involved in calorimetry it provides a survey of other important biological studies. The topics covered range from "pure" model biochemical systems to complex, intact, biological systems such as blood: also included are discussions of both practical and theoretical problems.

Author: Dénes Lörinczy
Publisher: Springer Science & Business Media
ISBN: 9781402022180
Category : Science
Languages : en
Pages : 368

View

Book Description
The Nature of Biological Systems as Revealed by Thermal Methods is a guide for experiments using thermal methods. The Editor has used his many years of experience to create a unique resource that will enable others with a less mathematical background, to realize the beauty and power of this tool and to gain a better understanding of biological problems. Biological calorimetry (and of course thermal analysis) is of increasing interest and is not covered thoroughly in other resources. The methods presented are macroscopic, for the rather inhomogeneous material (micromethods are often not possible or not pertinent). This book will help beginners in the field of thermal analysis or calorimetry understand the principles of thermodynamics being applied to biological systems. Biological systems are highly organized and very complex. The water and the different types of weak interactions among the macromolecules make the interpretation of thermal events very difficult. This book includes examples how to handle such problems. The Nature of Biological Systems as Revealed by Thermal Methods is unique in that it: -has a broad spectrum, from molecules and biochemistry, tissues, and food, to whole organisms; -combines practical problems (food processing, quality control, thermal denaturation of proteins, plants and small insects, etc.) with concrete solutions and interpretation; -provides practical strategies and tools without "dry physics and mathematics"; -initiates the application of thermal methods in new fields (e.g. medicine); -forces the reader to go into more detail of thermodynamics and thermal techniques; -simplifies communication between biologists, medical doctors and experts of thermal analysis. The book is an invaluable resource for anyone interested in thermodynamics, including practising professionals applying thermal methods to biological problems; researchers and graduate students beginning work using thermal methods; and specialists of thermal analysis starting work on biological problems. In addition, this book will be a useful resource for libraries and institutes as the only book covering quantitative thermal analysis of biological systems.

Author: I. Lamprecht
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110860716
Category : Science
Languages : en
Pages : 360

View

Book Description
No detailed description available for "Application of Calorimetry in Life Sciences".

Author: D Nes L?rinczy
Publisher: Springer
ISBN: 9786610461677
Category : Biological systems
Languages : en
Pages : 351

View

Book Description
The Nature of Biological Systems as Revealed by Thermal Methods is a guide for experiments using thermal methods. The Editor has used his many years of experience to create a unique resource that will enable others with a less mathematical background, to realize the beauty and power of this tool and to gain a better understanding of biological problems. Biological calorimetry (and of course thermal analysis) is of increasing interest and is not covered thoroughly in other resources. The methods presented are macroscopic, for the rather inhomogeneous material (micromethods are often not possible or not pertinent). This book will help beginners in the field of thermal analysis or calorimetry understand the principles of thermodynamics being applied to biological systems. Biological systems are highly organized and very complex. The water and the different types of weak interactions among the macromolecules make the interpretation of thermal events very difficult. This book includes examples how to handle such problems.; The Nature of Biological Systems as Revealed by Thermal Methods is unique in that it: The book is an invaluable resource for anyone interested in thermodynamics, including practising professionals applying thermal methods to biological problems; researchers and graduate students beginning work using thermal methods; and specialists of thermal analysis starting work on biological problems. In addition, this book will be a useful resource for libraries and institutes as the only book covering quantitative thermal analysis of biological systems.

Author:
Publisher: Elsevier
ISBN: 0444640630
Category : Technology & Engineering
Languages : en
Pages : 862

View

Book Description
Handbook of Thermal Analysis and Calorimetry: Recent Advances, Techniques and Applications, Volume Six, Second Edition, presents the latest in a series that has been well received by the thermal analysis and calorimetry community. This volume covers recent advances in techniques and applications that complement the earlier volumes. There has been tremendous progress in the field in recent years, and this book puts together the most high-impact topics selected for their popularity by new editors Sergey Vyazovkin, Nobuyoshi Koga and Christoph Schick—all editors of Thermochimica Acta. Among the important new techniques covered are biomass conversion; sustainable polymers; polymer nanocompsoties; nonmetallic glasses; phase change materials; propellants and explosives; applications to pharmaceuticals; processes in ceramics, metals, and alloys; ionic liquids; fast-scanning calorimetry, and more. Features 19 all-new chapters to bring readers up to date on the current status of the field Provides a broad overview of recent progress in the most popular techniques and applications Includes chapters authored by a recognized leader in each field and compiled by a new team of editors, each with at least 20 years of experience in the field of thermal analysis and calorimetry Enables applications across a wide range of modern materials, including polymers, metals, alloys, ceramics, energetics and pharmaceutics Overviews the current status of the field and summarizes recent progress in the most popular techniques and applications

Author: Margarida Bastos
Publisher: CRC Press
ISBN: 148224666X
Category : Medical
Languages : en
Pages : 412

View

Book Description
Connecting past, present, and future instrument development and use, Biocalorimetry: Foundations and Contemporary Approaches explores biocalorimetry's history, fundamentals, methodologies, and applications. Some of the most prominent calorimeter developers and users share invaluable personal accounts of discovery, discussing innovative techniques a

Author: Banafshe Larijani
Publisher: John Wiley & Sons
ISBN: 0470090669
Category : Science
Languages : en
Pages : 272

View

Book Description
Written by a team of international researchers and teachers at the cutting edge of chemical biology research, this book provides an exciting, comprehensive introduction to a wide range of chemical and physical techniques with applications in areas as diverse as molecular biology, signal transduction, drug discovery and medicine. Techniques include: Cryo-electron microscopy, atomic force microscopy, differential scanning calorimetry in the study of lipid structures, membrane potentials and membrane probes, identification and quantification of lipids using mass spectroscopy, liquid state NMR, solid state NMR in biomembranes, molecular dynamics, two dimensional infra-red studies of biomolecules, single and two-photon fluorescence, optical tweezers, PET imaging and chemical genetics. KEY FEATURES: a unique guide to the rapidly evolving, interdisciplinary field of chemical biology. adopts a molecular structure for maximum flexibility. addresses relevant, topical chemical biological questions throughout. includes stunning illustrations. associates website with PowerPoint slides of figures within the book. Chemical Biology: Techniques and Applications provides an invaluable resource for final year undergraduate and post graduate bioscience and biomedical students and pharmaceutical researchers with an interest in this fascinating, and ever changing field.