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Author: Frank W. Sellke Publisher: Elsevier Health Sciences ISBN: 0323790275 Category : Medical Languages : en Pages : 2794
Book Description
The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery—the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Features short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. - Presents the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty. - Provides full-color coverage throughout, helping you visualize challenging surgical techniques and procedures and navigate the text efficiently. - Includes new chapters on dissection complications and percutaneous treatment of mitral and tricuspid valve disease. - Offers extensively revised or rewritten chapters on surgical revascularization, acute dissection, vascular physiology, the latest innovations in minimally invasive cardiothoracic surgery and percutaneous devices, the molecular biology of thoracic malignancy, robotics in chest surgery, congenital valve reconstructions, novel hybrid procedures in pediatric cardiac surgery, and 3D visualization of cardiac anatomy for surgical procedure planning. - Keeps you up to date with the latest developments in cardiothoracic imaging and diagnosis. - Provides access to more than 30 surgical videos online, and features new figures, tables, and illustrations throughout. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Author: Frank W. Sellke Publisher: Elsevier Health Sciences ISBN: 0323790275 Category : Medical Languages : en Pages : 2794
Book Description
The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery—the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Features short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. - Presents the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty. - Provides full-color coverage throughout, helping you visualize challenging surgical techniques and procedures and navigate the text efficiently. - Includes new chapters on dissection complications and percutaneous treatment of mitral and tricuspid valve disease. - Offers extensively revised or rewritten chapters on surgical revascularization, acute dissection, vascular physiology, the latest innovations in minimally invasive cardiothoracic surgery and percutaneous devices, the molecular biology of thoracic malignancy, robotics in chest surgery, congenital valve reconstructions, novel hybrid procedures in pediatric cardiac surgery, and 3D visualization of cardiac anatomy for surgical procedure planning. - Keeps you up to date with the latest developments in cardiothoracic imaging and diagnosis. - Provides access to more than 30 surgical videos online, and features new figures, tables, and illustrations throughout. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Author: Steven Howard Publisher: Royal Society of Chemistry ISBN: 1782625658 Category : Medical Languages : en Pages : 314
Book Description
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Author: Dongyou Liu Publisher: CRC Press ISBN: 1040005640 Category : Science Languages : en Pages : 763
Book Description
With a history that likely dates back to the dawn of human civilization more than 10,000 years ago, and a record that includes the domestication and selective breeding of plants and animals, the harnessing of fermentation process for bread, cheese, and brewage production, and the development of vaccines against infectious diseases, biotechnology has acquired a molecular focus during the 20th century, particularly following the resolution of DNA double helix in 1953, and the publication of DNA cloning protocol in 1973, and transformed our concepts and practices in disease diagnosis, treatment and prevention, pharmaceutical and industrial manufacturing, animal and plant industry, and food processing. While molecular biotechnology offers unlimited opportunities for improving human health and well-being, animal welfare, agricultural innovation and environmental conservation, a dearth of high quality books that have the clarity of laboratory manuals without distractive procedural details and the thoroughness of well-conversed textbooks appears to dampen the enthusiasm of aspiring students. In attempt to fill this glaring gap, Handbook of Molecular Biotechnology includes four sections, with the first three presenting in-depth coverage on DNA, RNA and protein technologies, and the fourth highlighting their utility in biotechnology. Recognizing the importance of logical reasoning and experimental verification over direct observation and simple description in biotechnological research and development, the Introduction provides pertinent discussions on key strategies (i.e., be first, be better, and be different), effective thinking (lateral, parallel, causal, reverse, and random), and experimental execution, which have proven invaluable in helping advance research projects, evaluate and prepare research reports, and enhance other scientific endeavors. Key features Presents state-of-the-art reviews on DNA, RNA and protein technologies and their biotechnological applications Discusses key strategies, effective thinking, and experimental execution for scientific research and development Fills the gap left by detailed-ridden laboratory manuals and insight-lacking standard textbooks Includes expert contributions from international scientists at the forefront of molecular biotechnology research and development Written by international scientists at the forefront of molecular biotechnology research and development, chapters in this volume cover the histories, principles, and applications of individual techniques/technologies, and constitute stand-alone, yet interlinked lectures that strive to educate as well as to entertain. Besides providing an informative textbook for tertiary students in molecular biotechnology and related fields, this volume serves as an indispensable roadmap for novice scientists in their efforts to acquire innovative skills and establish solid track records in molecular biotechnology, and offers a contemporary reference for scholars, educators, and policymakers wishing to keep in touch with recent developments in molecular biotechnology.
Author: Allan Matte Publisher: Elsevier ISBN: 0081030193 Category : Business & Economics Languages : en Pages : 222
Book Description
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book. Covers the vital new area of R&D on therapeutic antibodies Written by leading scientists and researchers Up-to-date coverage and includes a detailed bibliography
Author: Benjamin F. Cravatt Publisher: Springer ISBN: 3030111431 Category : Medical Languages : en Pages : 420
Book Description
This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.
Author: Tanveer Ali Dar Publisher: Academic Press ISBN: 9780128119136 Category : Science Languages : en Pages : 0
Book Description
Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer's, Huntington's, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.
Author: Wei Wang Publisher: John Wiley & Sons ISBN: 1118043588 Category : Medical Languages : en Pages : 400
Book Description
This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.
Author: Frank W. Sellke
Author: Frank W. Sellke
Author: Steven Howard
Author: 
Author: Dr. R.C. Dubey
Author: Dongyou Liu
Author: Allan Matte
Author: Benjamin F. Cravatt
Author: Tanveer Ali Dar
Author: 
Author: Wei Wang