Novel Insights into Sperm Function and Selection: from Basic Research to Clinical Application PDF Download

Author: Kun Li
Publisher: Frontiers Media SA
ISBN: 2832536298
Category : Medical
Languages : en
Pages : 169

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Author: R. John Aitken
Publisher: Cambridge University Press
ISBN: 1108708315
Category : Health & Fitness
Languages : en
Pages : 247

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Book Description
A practical review of factors affecting male fertility and the treatments and strategies that can optimize IVF outcomes.

Author: Zsolt Peter Nagy
Publisher: Springer
ISBN: 3319430114
Category : Health & Fitness
Languages : en
Pages : 926

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Book Description
Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

Author: Paulo V. Brantus
Publisher: Nova Publishers
ISBN: 9781600216671
Category : Medical
Languages : en
Pages : 166

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Book Description
Seminomas account for about 30-40% of all testicular tumours. These are usually is found in men in their 30s and 40s. The condition is usually localised to the testes, although in about 25% of cases it has spread to lymph nodes. Non-seminomas account for 60% of all testicular tumours; subcategories of these tumours are listed below. Non-seminoma tumours often contain more than one of the following cell types: Testicular cancer is an abnormal, rapid, and invasive growth of cancerous (malignant) cells in the testicles. Embryonal carcinoma (about 20% of testicular cancers) occurs in 20-30 year olds and is highly malignant. It grows rapidly and spreads to the lung and liver. Yolk sac tumour (about 60% of all testicular cancers in young boys). Teratomata (about 7% of testicular cancers in adult men and 40% in young boys). Choriocarcinoma is rare. Stromal cell tumours are a kind of tumour that is made of Leydig cells (testosterone-secreting cells), Sertoli cells (cells where sperm matures), and granulose cells. These tumours account for only 3-4% of all testicular tumours. However, they do make up nearly 20% of all childhood testicular tumours. These tumours may secrete a hormone -- estradiol -- that can cause one of the symptoms of testicular cancer, gynecomastia (excessive development of breast tissue). This book presents leading-edge research in the field.

Author: Jamie Bernard
Publisher: Frontiers Media SA
ISBN: 2832555683
Category : Medical
Languages : en
Pages : 88

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The best way to reduce the overall cancer burden is to prevent cancer through a healthy lifestyle, pharmacological strategies, or decreased exposure to environmental carcinogens. Molecular chemical carcinogenesis, identification and evaluation of carcinogenicity hazards, and precision prevention drug discovery have highlighted key cellular, genetic, and epigenetic mechanisms of carcinogenesis that can inform prevention strategies on multiple levels. In this Research Topic, we propose to generate a collection of articles that discuss the main and newly-explored cellular, genetic, and epigenetic targets for cancer prevention, including the immune system. We aim to gain an in-depth understanding of cancer prevention from the molecular to the epidemiological consensus. In particular, these articles will focus on identified mechanisms in tumor initiation, promotion, and malignant transformation for precision prevention and environmental health.

Author: Wael Mohamed
Publisher: CRC Press
ISBN: 1040115896
Category : Science
Languages : en
Pages : 315

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Book Description
The increasing demand for innovative techniques arises from the lack of safe, effective, and patient-friendly therapies for neurodegenerative disorders. With this objective in mind, the chapters of the book are structured to offer a thorough insight into recent advancements in utilizing the zebrafish (ZF) as a model for studying Parkinson’s disease (PD). This book aims to present readers with a comprehensive understanding of the clinical application of the ZF model in treating PD, encompassing the latest developments, challenges, safety considerations, toxicity issues, regulatory aspects, future potential, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain stand to benefit from this resource. Key Features Provides a comparative perspective of the zebrafish–Parkinson’s disease model Highlights the restrictions of available medicines Describes biochemical and histopathological characteristics, advantages, and disadvantages of this model Emphasizes distinct facets of histopathology Presents advances and developments of the future potential perspectives

Author: Claude Gagnon
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 536

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Author: Sijo J. Parekattil
Publisher: Springer Nature
ISBN: 3030323005
Category : Health & Fitness
Languages : en
Pages : 895

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Book Description
A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that antioxidants play in male infertility. World-renowned experts in these areas have been selected to participate in this work. Careful selection of the highest quality content will span the whole range of topics in the area of male infertility, providing a complete review of well-established and current diagnostic and treatment techniques for male infertility. The incorporation of 20 new chapters will enhance the book’s appeal by including the most recent advances brought to the male infertility arena. Additionally, this edition incorporates new features, including bulleted key points, review criteria and select video clips demonstrating some of the most fascinating male infertility treatment modalities. A dedicated new section on current guidelines on male infertility will enlighten readers on how to most optimally manage male infertility clinical scenarios. Covering all aspects of diagnosis and management, ART, lifestyle factors and associated conditions for male infertility, Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants will be a readily accessible, high quality reference for medical students and residents, and will be of significant value to professionals working in the various fields treating this condition as well.

Author: Muneeb U Rehman
Publisher: Academic Press
ISBN: 0323903355
Category : Medical
Languages : en
Pages : 412

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Book Description
A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. - Contains exclusive information about research on immunogenetics from around the globe - Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications - Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Author: Elisabetta Baldi
Publisher: Springer
ISBN: 3030216640
Category : Medical
Languages : en
Pages : 216

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Book Description
There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.