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Author: Kurt Wuthrich Publisher: World Scientific ISBN: 9814500496 Category : Science Languages : en Pages : 760
Book Description
The volume presents a survey of the research by Kurt Wüthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.
Author: Kurt Wuthrich Publisher: World Scientific ISBN: 9814500496 Category : Science Languages : en Pages : 760
Book Description
The volume presents a survey of the research by Kurt Wüthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.
Author: Kurt Wthrich Publisher: World Scientific ISBN: 9789810223847 Category : Science Languages : en Pages : 770
Book Description
The volume presents a survey of the research by Kurt Wthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.
Author: Kurt Wüthrich Publisher: World Scientific Publishing Company ISBN: 9789811235788 Category : Science Languages : en Pages : 270
Book Description
The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.
Author: John L. Markley Publisher: Oxford University Press ISBN: 0195094689 Category : Medical Languages : en Pages : 375
Book Description
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.
Author: A. Haase Publisher: World Scientific ISBN: 9789810230852 Category : Science Languages : en Pages : 726
Book Description
To honour W C Rntgen and review the entire area of X-ray development in the various fields of natural, technical, and life sciences, his successors at the Physikalisches Institut of the Universitt Wrzburg organized a conference, named ?Rntgen Centennial?. It took place at the new ?Physikalisches Institut? not far from the historical site shortly before the actual 100th anniversary of the discovery. Over forty renowned scientists were invited as representative speakers in the various subfields of X-ray activities. They reviewed the development, gave examples, and described the present status. Most of them provided survey articles, which are gathered in this book. Since most X-ray-related activities are somehow represented, an almost complete overview of the entire field is provided. This book thus represents the enormous breadth of X-ray activities and allows one to recognize the potential and quality of today's X-ray research.
Author: Kurt Wüthrich Publisher: Wiley-Interscience ISBN: Category : Medical Languages : en Pages : 330
Book Description
Lists of tables. The foundations: structure and NMR of biopolymers. Resonance assignments and structure determination in proteins. Resonance assignments and structure determiantion in nucleic acids. With NMR to biopolymer conformation and beyond.
Author: Per Ahlberg Publisher: World Scientific Publishing Company ISBN: 9789812794444 Category : Biography & Autobiography Languages : en Pages : 500
Book Description
A collection of the Nobel Lectures delivered by the prizewinners in chemistry, together with their biographies, portraits and the presentation speeches.
Author: Atta-ur Rahman Publisher: Elsevier ISBN: 0080541496 Category : Science Languages : en Pages : 447
Book Description
Solving Problems with NMR Spectroscopy presents the basic principles and applications of NMR spectroscopy with only as much math as is necessary. It shows how to solve chemical structures with NMR by giving clear examples and solutions. This text will enable organic chemistry students to choose the most appropriate NMR techniques to solve specific structures. The problems to work and the discussion of their solutions and interpretations will help readers becomeproficient in the application of important, modern 1D and 2D NMR techniques to structural studies.Key Features* Presents the most important NMR techniques for structural determinations* Offers a unique problem-solving approach* Uses questions and problems, including discussions of their solutions and interpretations, to help readers grasp NMR* Avoids extensive mathematical formulas* Forewords by Nobel Prize winner Richard R. Ernst and Lloyd M. Jackman
Author: Kurt Wuthrich
Author: Kurt Wuthrich
Author: Kurt Wthrich
Author: Kurt Wüthrich
Author: John L. Markley
Author: A. Haase
Author: Kurt Wüthrich![Determination of the Structural Factors Contributing to the Bioactivity of TGF-[beta] Analogs PDF](https://books.google.com/books/content/images/frontcover/DjyReg2Ky24C?fife=w80-h100)
Author: Erika Whitney
Author: Per Ahlberg
Author: Atta-ur Rahman
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