Nitric Oxide in Transplant Rejection and Anti-Tumor Defense PDF Download

Author: Stanislaw Lukiewicz
Publisher: Springer Science & Business Media
ISBN: 1461550815
Category : Medical
Languages : en
Pages : 503

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Book Description
Nitric Oxide in Transplant Rejection and Anti-Tumor Defense represents a unique combination of three interrelated topics that is unavailable in any other single work: The detection and visualization of nitric oxide in biological materials using EPR spectroscopy and EPR imaging; Nitric oxide in immune mechanisms of allograft rejection; and The involvement of nitric oxide in anti-tumor defense. By bringing together specialists from these three disciplines, the book investigates the common molecular and cellular mechanisms underlying phenomena in transplants and oncology. In addition, the book provides an introduction to biological applications of EPR spectroscopy and imaging. Nitric Oxide in Transplant Rejection and Anti-Tumor Defense will appeal to researchers and graduate-level students investigating transplant rejections and their immune mechanisms, anti-tumor immune defenses, novel types of contrast agents for EPR imaging, and biological applications of EPR spectroscopy and EPR imaging.

Author: Lester Packer
Publisher: Gulf Professional Publishing
ISBN: 9780121822026
Category : Antioxidants
Languages : en
Pages : 636

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Book Description
General Description of the Volume: Nitric Oxide, recently designated "Molecule of the Year," impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume will be a valuable resource for the experienced researcher as well as for those newly entering the field. This volume continues the coverage of new and important tools for the elucidation of Nitric Oxide action initiated in Volumes 268 and 269 of Methods in Enzymology. Techniques for researching the physiology and toxicity of nitric oxide in cellular and organismal systems are highlighted. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Biological Activity * NO Donors: Nitrosothiols and Nitroxyls * Peroxynitrite * Oxidant and Antioxidant Action.

Author: Giuseppe Cicco
Publisher: Springer Science & Business Media
ISBN: 0387295402
Category : Science
Languages : en
Pages : 393

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Book Description
This book covers the proceedings of the 32nd scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) in Bari, Italy, August 21-26, 2004. It covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special emphasis is placed on methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. The event hosted was a multidisciplinary meeting designed to bring together experts and students from a range of research fields.

Author: Rui Wang
Publisher: Springer Science & Business Media
ISBN: 1592598064
Category : Medical
Languages : en
Pages : 372

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Book Description
Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.

Author: Ernst van Faassen
Publisher: Elsevier
ISBN: 0080489591
Category : Science
Languages : en
Pages : 444

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Book Description
Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. - First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes - Extensive bibliographic references, written by specialists of human physiology - Providing high scientific quality with a focus on implications for human diseases

Author:
Publisher: Elsevier
ISBN: 0080497039
Category : Science
Languages : en
Pages : 553

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Book Description
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. - Presents information on nitrosothiols and nitric oxide in cell signaling - Details nitric oxide and mitochondrial functions - Explains nitric oxide synthases

Author: Lawrence J. Berliner
Publisher: Springer Science & Business Media
ISBN: 1461500613
Category : Medical
Languages : en
Pages : 670

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Book Description
In Vivo EPR (ESR) is a textbook on this relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation as well as the latest applications at the time of its writing. The authors are world-renowned experts and pioneers in their fields. This book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging. Key Features: -History of In Vivo EPR, -Principles of Imaging-Theory and Instrumentation, -Time-domain Radio Frequency EPR Imaging, -The Measurement of Oxygen In Vivo Using In Vivo EPR Techniques, -Potential Medical (Clinical) Applications of EPR, -Combining NMR and EPR/ESR for In Vivo Experiments.

Author: A.R Hargens
Publisher: ALPHA SCIENCE INTERNATIONAL LIMITED
ISBN: 8184872895
Category : Medical
Languages : en
Pages : 357

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Book Description
Recognition of adaptive processes in biological systems as a discipline is still in its infancy. It is known that repeat exposure to low level stresses such as heat, cold, microgravity, hypoxia, exercise, etc. increases body-resistance to not only the particular stress but also to other conditions. Such a cross-protection can be utilized in a better patient care. This volume describes most current developments in the understanding of the molecular basis of adaptation as well as its application in biological systems including certain disease conditions in humans. The book is based on the presentations made by internationally known experts assembled in San Diego, USA for the 7th World Congress of the International Society for Adaptive Medicine and will be of great interest to experimental biologists as well as clinicians who deal with a wide variety of clinical conditions.

Author: A. Hargens
Publisher: Alpha Science Int'l Ltd.
ISBN: 9788173195716
Category : Medical
Languages : en
Pages : 366

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Book Description
Recognition of adaptive processes in biological systems as a discipline is still in its infancy. It is known that repeat exposure to low level stresses such as heat, cold, microgravity, hypoxia, exercise, etc. increases body-resistance to not only the particular stress but also to other conditions. Such a cross-protection can be utilized in a better patient care. This volume describes most current developments in the understanding of the molecular basis of adaptation as well as its application in biological systems including certain disease conditions in humans. The book is based on the presentations made by internationally known experts assembled in San Diego, USA for the 7th World Congress of the International Society for Adaptive Medicine and will be of great interest to experimental biologists as well as clinicians who deal with a wide variety of clinical conditions.

Author: Sandra S. Eaton
Publisher: Springer Science & Business Media
ISBN: 0387267417
Category : Medical
Languages : en
Pages : 536

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Book Description
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features: Free Radicals in Medicine Radicals in vivo and in Model Systems, and their Study by Spin Trapping In vivo EPR, including Oximetry and Imaging Time Domain EPR at Radio Frequencies EPR of Copper Complexes: Motion and Frequency Dependence Time Domain EPR and Electron Spin Echo Envelope Modulation