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Author: Fumihiko Kimura Publisher: Springer Science & Business Media ISBN: 1848002661 Category : Business & Economics Languages : en Pages : 555
Book Description
Collected here are 112 papers concerned with new directions in manufacturing systems, given at the 41st CIRP Conference on Manufacturing Systems. The high-quality material includes reports of work from both scientific and engineering standpoints.
Author: Fumihiko Kimura Publisher: Springer Science & Business Media ISBN: 1848002661 Category : Business & Economics Languages : en Pages : 555
Book Description
Collected here are 112 papers concerned with new directions in manufacturing systems, given at the 41st CIRP Conference on Manufacturing Systems. The high-quality material includes reports of work from both scientific and engineering standpoints.
Author: James A. Jordan Publisher: Wiley-Interscience ISBN: Category : Business & Economics Languages : en Pages : 468
Book Description
Based on the NGM paradigm that defines manufacturing practices, this work offers a framework for the operational strategies, product development techniques, metrics and knowledge management approaches that lead to manufacturing excellence. It includes examples from the 15 participating firms.
Author: Rosanna Fornasiero Publisher: Springer Nature ISBN: 3030635058 Category : Technology & Engineering Languages : en Pages : 298
Book Description
This open access book explores supply chains strategies to help companies face challenges such as societal emergency, digitalization, climate changes and scarcity of resources. The book identifies industrial scenarios for the next decade based on the analysis of trends at social, economic, environmental technological and political level, and examines how they may impact on supply chain processes and how to design next generation supply chains to answer these challenges. By mapping enabling technologies for supply chain innovation, the book proposes a roadmap for the full implementation of the supply chain strategies based on the integration of production and logistics processes. Case studies from process industry, discrete manufacturing, distribution and logistics, as well as ICT providers are provided, and policy recommendations are put forward to support companies in this transformative process.
Author: Frank T. Piller Publisher: Springer Nature ISBN: 3031077342 Category : Business & Economics Languages : en Pages : 169
Book Description
Manufacturing companies have just begun to implement the concepts of the Fourth Industrial Revolution (Industry 4.0) on a larger scale. Still, this area is characterized by a rapid pace of technological change, blurring boundaries between physical, digital, and biological systems, and a quickly changing growing political, economic, and social environment -- leading to high uncertainty in decision making and many questions about the future development in this field. To provide guidance and inspiration for managers and academics on the future of digital manufacturing systems, this book presents the results of an extensive Delphi study on next-generation manufacturing systems, with a projection period of up to 2030. We analyzed almost 2000 quantitative estimations and more than 600 qualitative arguments from a large panel of industrial and academic experts from Europe, North America, and Asia. The book describes each of the 24 projections in detail, offering current case study examples and related research, as well as implications for policymakers, firms, and individuals. The empirical results also allowed us to build scenarios for the most probable future along the dimensions of governance, organization, capabilities, and interfaces from both a company-internal and an external (network) perspective.
Author: Michael E. McGrath Publisher: McGraw Hill Professional ISBN: 0071435123 Category : Business & Economics Languages : en Pages : 400
Book Description
This guidebook gives R & D professionals an in-depth explanation of ways companies are able to achieve substantially higher levels of development productivity; while better aligning product development with strategy through new practices and systems. --
Author: Marc Damelin Publisher: Springer ISBN: 3319781545 Category : Medical Languages : en Pages : 358
Book Description
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Author: William B. Bonvillian Publisher: MIT Press ISBN: 0262037033 Category : Business & Economics Languages : en Pages : 417
Book Description
How to rethink innovation and revitalize America's declining manufacturing sector by encouraging advanced manufacturing, bringing innovative technologies into the production process. The United States lost almost one-third of its manufacturing jobs between 2000 and 2010. As higher-paying manufacturing jobs are replaced by lower-paying service jobs, income inequality has been approaching third world levels. In particular, between 1990 and 2013, the median income of men without high school diplomas fell by an astonishing 20% between 1990 and 2013, and that of men with high school diplomas or some college fell by a painful 13%. Innovation has been left largely to software and IT startups, and increasingly U.S. firms operate on a system of “innovate here/produce there,” leaving the manufacturing sector behind. In this book, William Bonvillian and Peter Singer explore how to rethink innovation and revitalize America's declining manufacturing sector. They argue that advanced manufacturing, which employs such innovative technologies as 3-D printing, advanced material, photonics, and robotics in the production process, is the key. Bonvillian and Singer discuss transformative new production paradigms that could drive up efficiency and drive down costs, describe the new processes and business models that must accompany them, and explore alternative funding methods for startups that must manufacture. They examine the varied attitudes of mainstream economics toward manufacturing, the post-Great Recession policy focus on advanced manufacturing, and lessons from the new advanced manufacturing institutes. They consider the problem of “startup scaleup,” possible new models for training workers, and the role of manufacturing in addressing “secular stagnation” in innovation, growth, the middle classes, productivity rates, and related investment. As recent political turmoil shows, the stakes could not be higher.
Author: Fumihiko Kimura
Author: Fumihiko Kimura
Author: James A. Jordan
Author: James A. Jordan
Author: Jim Jordan PhD
Author: Rosanna Fornasiero
Author: Frank T. Piller
Author: Michael E. McGrath
Author: Technologies Enabling Agile Manufacturing
Author: Marc Damelin
Author: William B. Bonvillian