New Therapeutics for Traumatic Brain Injury PDF Download

Author: Kim Heidenreich
Publisher: Academic Press
ISBN: 0128027010
Category : Psychology
Languages : en
Pages : 354

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Book Description
New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. - Comprehensive overview of basic approaches and translational development of new therapies for TBI - Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field - Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic

Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 388

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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486890
Category : Medical
Languages : en
Pages : 211

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Book Description
The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.

Author: Jack W. Tsao
Publisher: Springer Nature
ISBN: 3030224368
Category : Medical
Languages : en
Pages : 465

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Book Description
This thoroughly revised and updated work covers numerous advances in traumatic brain injury diagnosis, evaluation, treatment, and pathophysiology. Since publication of the first edition in 2012, there has been greatly increased public awareness of the clinical consequences of even the mildest of head injuries, and the result has been a concerted effort of countries around the world to increase research funding. This second edition continues to focus on mild traumatic brain injury--or concussion--and contains updates to all the original chapters as well as adding new chapters addressing clinical sequelae, including pediatric concussion, visual changes, chronic traumatic encephalopathy, and blast-associated TBI. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, is a comprehensive resource designed for neurologists, primary care clinicians, sports physicians, and other medical providers, including psychologists and neuropsychologists, as well as athletic trainers who may evaluate and care for individuals who have sustained a TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies, and an updated appendix of ICD codes is included. An outstanding contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, again offers an invaluable resource for all providers who treat patients with TBI.

Author: Simon Gilbertson
Publisher: Jessica Kingsley Publishers
ISBN: 1846428289
Category : Psychology
Languages : en
Pages : 161

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Book Description
Musical improvisation is an increasingly recognised rehabilitative therapy for people who have experienced traumatic brain injury initially thought to be `unreachable' or `non-responsive'. Music Therapy and Traumatic Brain Injury demonstrates how music therapy can be used to attend to the holistic, rather than purely functional, needs of people affected by severe head trauma. Divided into three parts, the first section provides an introduction to the effects brain injury has on a person's livelihood. The second is a comprehensive review of available literature on the use of music therapy in the neurorehabilitative setting. The final section examines three case studies designed according to `therapeutic narrative analysis', an adaptive research method that uses interviewing and video, which focuses on the unique relationship between the professional and the patient. This book will give clinicians key notes for practice and a vision of the integral role music therapy can have in the successful rehabilitation from brain injury.

Author: Jonathan M. Silver, M.D.
Publisher: American Psychiatric Pub
ISBN: 1615371125
Category : Medical
Languages : en
Pages : 996

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Book Description
Despite the increased public awareness of traumatic brain injury (TBI), the complexities of the neuropsychiatric, neuropsychological, neurological, and other physical consequences of TBI of all severities across the lifespan remain incompletely understood by patients, their families, healthcare providers, and the media. Keeping pace with advances in the diagnosis, treatment, and science of TBI, the Textbook of Traumatic Brain Injury, Third Edition, comprehensively fills this gap in knowledge. Nearly all 50 chapters feature new authors, all of them experts in their field. Chapters new to this edition include biomechanical forces, biomarkers, neurodegenerative dementias, suicide, endocrine disorders, chronic disease management, and social cognition. An entirely new section is devoted to the evaluation and treatment of mild TBI, including injuries in athletes, military service members and veterans, and children and adolescents. These chapters join newly updated sections on the assessment and treatment of the cognitive, emotional, behavioral, and other physical sequelae of TBI. The Textbook of Traumatic Brain Injury is a must-read for all of those working in any of the multitude of disciplines that contribute to the care and rehabilitation of persons with brain injury. This new volume is also a potentially useful reference for policymakers in both the public and private sectors.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309218187
Category : Medical
Languages : en
Pages : 356

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Book Description
Traumatic brain injury (TBI) may affect 10 million people worldwide. It is considered the "signature wound" of the conflicts in Iraq and Afghanistan. These injuries result from a bump or blow to the head, or from external forces that cause the brain to move within the head, such as whiplash or exposure to blasts. TBI can cause an array of physical and mental health concerns and is a growing problem, particularly among soldiers and veterans because of repeated exposure to violent environments. One form of treatment for TBI is cognitive rehabilitation therapy (CRT), a patient-specific, goal-oriented approach to help patients increase their ability to process and interpret information. The Department of Defense asked the IOM to conduct a study to determine the effectiveness of CRT for treatment of TBI.

Author: Deborah Caruso, MD
Publisher: Demos Medical Publishing
ISBN: 1935281798
Category : Medical
Languages : en
Pages : 197

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Book Description
Practitioners today see increasing numbers of brain injuries across the country and around the glozbe. The causes run the gamut of human endeavor, from frailty associated with aging, military activity, sports, and motor vehicle accidents of all kinds. With a growing awareness of the effects of traumatic brain injury (TBI) and the need for early intervention to ameliorate these effects and improve patient outcomes have come demand for practical information for clinicians on the "frontlines." Designed for the busy practitioner Traumatic Brain Injury: Rehabilitation Medicine Quick Reference is a handy reference providing quick answers when diagnosing and treating traumatic brain injuries at every level. One hundred alphabetically listed topics are presented in a consistent two-page format for easy access to key information at a glance. The book covers assessment, diagnostic testing, and the full spectrum of brain injury conditions, sequelae, and interventions commonly associated with TBI and expected functional outcomes. Specialized areas of TBI care are alos included for unique patient populations, such as sports or military injury, and conditions such as post-traumatic stress disorder or neuroendocrine disorder, that may be seen by providers in other settings. Every entry is standardized for quick look-up in the office or clinic, and features description, etiology, risk factors, clinical features, natural history, diagnosis, red flags, treatment, prognosis, helpful hints, and suggested readings.All Rehabilitation Medicine Quick Referencetitles offer: Consistent Approach and Organization: at-a-glance outline format allows readers to find the facts quickly Concise Coverage: of must-know information broken down into easy-to-locate topics Fast Answers to Clinical Questions: diagnostic and management criteria for problems commonly encountered in daily practice Hands-on Practical Guidance: for all types of interventions and therapies Multi-Specialty Perspective: ensures that issues of relevance to all rehabilitation team members are addressed

Author: Svetlana Dambinova
Publisher: Royal Society of Chemistry
ISBN: 1849733899
Category : Medical
Languages : en
Pages : 247

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Book Description
Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.