Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF Download

Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF full book. Access full book title Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research by National Academies of Sciences, Engineering, and Medicine. Download full books in PDF and EPUB format.

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309488516
Category : Science
Languages : en
Pages : 123

Book Description
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309488516
Category : Science
Languages : en
Pages : 123

Book Description
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research PDF Author: Robert P. Marini
Publisher: Academic Press
ISBN: 012811830X
Category : Science
Languages : en
Pages : 572

Book Description
The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

The Smallest Anthropoids

The Smallest Anthropoids PDF Author: Susan M. Ford
Publisher: Springer Science & Business Media
ISBN: 1441902937
Category : Science
Languages : en
Pages : 493

Book Description
Here is a comprehensive examination of the newly recognized callimico/marmoset clade, which includes the smallest anthropoid primates on earth. It features sections on phylogeny, taxonomy and functional anatomy, behavioral ecology, and reproductive physiology.

The Psychological Well-Being of Nonhuman Primates

The Psychological Well-Being of Nonhuman Primates PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309176506
Category : Science
Languages : en
Pages : 183

Book Description
A 1985 amendment to the Animal Welfare Act requires those who keep nonhuman primates to develop and follow appropriate plans for promoting the animals' psychological well-being. The amendment, however, provides few specifics. The Psychological Well-Being of Nonhuman Primates recommends practical approaches to meeting those requirements. It focuses on what is known about the psychological needs of primates and makes suggestions for assessing and promoting their well-being. This volume examines the elements of an effective care programâ€"social companionship, opportunities for species-typical activity, housing and sanitation, and daily care routinesâ€"and provides a helpful checklist for designing a plan for promoting psychological well-being. The book provides a wealth of specific and useful information about the psychological attributes and needs of the most widely used and exhibited nonhuman primates. Readable and well-organized, it will be welcomed by animal care and use committees, facilities administrators, enforcement inspectors, animal advocates, researchers, veterinarians, and caretakers.

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment PDF Author: Joerg Bluemel
Publisher: Academic Press
ISBN: 012417146X
Category : Medical
Languages : en
Pages : 716

Book Description
The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. - Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more - Includes practical examples on techniques and methods to guide your daily practice - Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

Reproduction in New World Primates

Reproduction in New World Primates PDF Author: J.P. Hearn
Publisher: Springer Science & Business Media
ISBN: 9400973225
Category : Medical
Languages : en
Pages : 219

Book Description
The New World primates are becoming widely used in scientific and medical work in fields from anthropology to zoology, behaviour to urology. They have unique attributes for studies in cancer, infectious diseases, genetics, virology and reproduction. However, it is only now that their reproductive physiology is being clarified in any depth and this book is a first synthesis of that knowledge. The nine authors involved in this project have presented an up to date account of the major New World species used in biological and medical science. In addition to their distribution and conservation in the wild, essential biological data from laboratory studies are presented on reproductive cycles, gestation length, seasonal breeding, puberty and other factors. The major applications of these species in research are explored. Whenever possible, research workers should steer away from using endangered species in their studies. The New World monkeys used in research in any numbers are still fairly common ~n the wild, yet their greatest advantages are ~n their smalle size and high fecundity. This makes possible the establishment of self sustaining captive breeding colonies at a fraction of the time and cost necessary for the more conventional Old World laboratory primates. Consequently the drain on wild stocks need not be extensive as only breeding nuclei should be necessary.

Marmosets and Tamarins

Marmosets and Tamarins PDF Author: Anthony B. Rylands
Publisher: Oxford Science Publications
ISBN: 9780198540229
Category : Science
Languages : en
Pages : 0

Book Description
Starting with concise accounts for all the marmoset and tamarin monkeys species, this important new book then goes on to review their geographical distributions and taxonomy, along with comparative reviews of vocalizations, scent-marking, mating systems, infant care and development, social organization, and behavior and ecology in the wild. Several of these small-primate species are rare or threatened, and the subjects discussed here are strongly relevant to their management in captivity as well as for understanding natural populations. This is the first volume in several years to review current knowledge of this family, which comprises 52 species and subspecies found in the area from Panama to southern Brazil.

Horned Armadillos and Rafting Monkeys

Horned Armadillos and Rafting Monkeys PDF Author: Darin A. Croft
Publisher: Indiana University Press
ISBN: 0253020948
Category : Science
Languages : en
Pages : 321

Book Description
A thrilling guide to the Cenozoic mammals of South America, featuring seventy-five life reconstructions of extinct species, plus photos of specimens and sites. South America is home to some of the most distinctive mammals on Earth—giant armadillos, tiny anteaters, the world’s largest rodent, and its smallest deer. But the continent once supported a variety of other equally intriguing mammals that have no close living relatives: armored mammals with tail clubs, saber-toothed marsupials, and even a swimming sloth. We know of the existence of these peculiar species thanks to South America’s rich fossil record, which provides many glimpses of prehistoric mammals and the ecosystems in which they lived. Organized as a “walk through time” and featuring species from fifteen important fossil sites, this book is the most extensive and richly illustrated volume devoted exclusively to the Cenozoic mammals of South America. The text is supported by seventy-five life reconstructions of extinct species in their native habitats, as well as photographs of fossil specimens and the sites highlighted in the book. An annotated bibliography is included for those interested in delving into the scientific literature. “Well-written and easy for the nonspecialist to understand, this is also a most needed updating of this subject, much in the line of classic works such as Simpson’s The Beginning of the Age of Mammals in South America and Patterson and Pascual’s The Fossil Mammal Fauna of South America.” —Richard Fariña, coauthor Megafauna: Giant Beasts of Pleistocene South America “This handsome book, written by a leading expert in South American paleontology, is profusely illustrated with maps, time charts, color photographs of fossils, and exquisite life reconstructions. The book . . . will appeal to any individual, young and old alike, interested in the fossil record, as well as to students and scholars of paleontology who work in other parts of the globe.” —Choice

Marmosets and Tamarins

Marmosets and Tamarins PDF Author: Anthony B. Rylands
Publisher: Conservation International Tropical Pocket Guide Series
ISBN: 9781934151204
Category : Marmosets
Languages : en
Pages : 20

Book Description
Laminated identification guide illustrating 61 species and subspecies of extant marmosets and tamarins in Central and South America. Includes range maps.

Finger Monkey Pet. What You Need to Know. Finger Monkey Or Pygmy Marmoset Information. Pygmy Marmoset Care, Environment, Behaviour, Feeding and Health.

Finger Monkey Pet. What You Need to Know. Finger Monkey Or Pygmy Marmoset Information. Pygmy Marmoset Care, Environment, Behaviour, Feeding and Health. PDF Author: Harry Holdstone
Publisher: Pesa Publishing Finger Monkey Pygmy Marmoset
ISBN: 9781912057887
Category :
Languages : en
Pages :

Book Description
The Pygmy Marmoset or Finger Monkey is the smallest True Monkey and the second smallest primate in the world. These primates are intelligent, acrobatic, energetic, fun to watch... and a lot of work. This readable book provides a great deal of helpful factual and practical information on this species of New World Monkey including what it needs in order to be happy and healthy. If you are considering buying a Pygmy Marmoset you will find honest information about the advantages and disadvantages of these tiny primates so that you can make a balanced and considered decision that takes their nature and needs, your personality and your lifestyle into account. If you already own a Finger monkey, the contents of this book will help you to make the most of your exotic and demanding pet and keep him or her well cared for. There are a number of practical tips, lists and checklists to help you to become the owner your primate friend needs you to be. For those who already have these off-the-chart cute creatures and are considering breeding with them, this book is for you too as it provides general information about mating, pregnancy and birth and the rigours of hand-rearing these vulnerable infants. Finally, this book is for all those people who are just interested to learn about this species. Covered in this book: - Are they good pets? - Basics - Behaviour - Costs - Development - Do's and Don'ts - Enclosure - Feeding - General care - Health - Interaction - Personality - Safety tips - Training - Treats .... and much more