Author: Kevan Michael ShokatPublisher:
ISBN:
Category :
Languages : en
Pages : 572
Book Description
New Routes of Catalytic Antibodies
Author: Kevan Michael ShokatPublisher:
ISBN:
Category :
Languages : en
Pages : 572
Book Description
Routes to Catalysis
Author: Matthew R. HaynesCatalytic Antibodies
Author: Ehud KeinanPublisher: John Wiley & Sons
ISBN: 3527605053
Category : Science
Languages : en
Pages : 616
Book Description
Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: * theoretical aspects of structure, mechanism and kinetics * practical considerations, from immunization techniques to screening methods * in vitro evolution and other modern approaches * applications from organic synthesis to medical uses. Backed by the leading authorities in antibody catalysis, this is the first book to provide such comprehensive coverage and constitutes a prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.
Catalytic Antibodies
Author: Derek J. ChadwickPublisher: John Wiley & Sons
ISBN: 0470514116
Category : Science
Languages : en
Pages : 270
Book Description
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.
Catalytic Antibodies
Author: Sudhir PaulPublisher: Karger Medical and Scientific Publishers
ISBN: 3805570996
Category : Medical
Languages : en
Pages : 172
Book Description
This volume addresses fundamental questions concerning the immunological genesis of the catalytic activity in antibodies, its relationship with classical antigen binding activity, and the biochemical mechanisms involved in catalysis. The contents reflect three main challenges in the field, i.e. to delineate the biological functions of catalytic antibodies in autoimmune disease; to isolate therapy-grade antibody catalysts with sufficient specificity and turnover to permit rapid removal of microbial and tumor antigens; and to develop immunogens that recruit immature catalyst-producing B cells into the clonal selection pathway and induce adaptive improvements of the catalytic function. Well-edited and up-to-date, this book reviews the current knowledge in the field and explores ways by which natural and engineered catalytic activities can be harnessed for medical applications. It should therefore be of special interest to immunologists, biochemists, biotechnologists, rheumatologists and pathologists.
New Directions in Catalytic Antibodies
Author: Grace Reiko NakayamaPublisher:
ISBN:
Category :
Languages : en
Pages : 614
Book Description
Germinal Centers
Author: Meredith L. HowardPublisher:
ISBN:
Category : B cells
Languages : en
Pages : 132
Book Description
New Approaches to Catalytic Antibodies
Author: Scott Jeffrey PollackPublisher:
ISBN:
Category :
Languages : en
Pages : 640
Book Description
Catalytic Antibodies
Author: Andrew Charles BraistedPublisher:
ISBN:
Category :
Languages : en
Pages : 546
Book Description
Catalytic Antibodies
Author: Jeffrey William JacobsPublisher:
ISBN:
Category : Haptens
Languages : en
Pages : 276
Book Description