New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Prognostic and Predictive Biomarkers and Therapy PDF Download

Author: Hao Wang
Publisher: Frontiers Media SA
ISBN: 2889744086
Category : Science
Languages : en
Pages : 194

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Book Description
Publisher’s note: This is a 2nd edition due to an article retraction.

Author: Nicolai Stanislas van Oers
Publisher: Frontiers Media SA
ISBN: 2889662683
Category : Medical
Languages : en
Pages : 228

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author: Jérôme Paggetti
Publisher: Frontiers Media SA
ISBN: 2889742075
Category : Medical
Languages : en
Pages : 127

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Author: Marita Bosticardo
Publisher: Frontiers Media SA
ISBN: 2889714497
Category : Medical
Languages : en
Pages : 177

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Author: Mitra Ranjbar
Publisher: BoD – Books on Demand
ISBN: 1789850975
Category : Medical
Languages : en
Pages : 158

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Book Description
Brucellosis is an important zoonotic disease. More than half a million new cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of patients are living in developing countries. Brucellosis is a systemic infection with a broad clinical spectrum, ranging from an asymptomatic disease to a severe and fatal illness. Clinical and laboratory features vary widely. The main presentations are acute febrile illness, localized infection, and chronic infection. Laboratory tools for diagnosis of brucellosis include culture, serology, and polymerase chain reaction (PCR). The goal of brucellosis therapy is to control the illness and prevent complications, relapses, and sequelae. Important principles of brucellosis treatment include use of antibiotics with activity in the acidic intracellular environment, use of combination regimens, and prolonged duration of treatment. This book is the result of several months of outstanding efforts by the authors and the revision of the content by experts in the field of brucellosis. This book is a valid resource and is intended for everyone interested in infectious disease to learn the most important aspects of brucellosis.

Author: Mary Poupot-Marsan
Publisher: Frontiers Media SA
ISBN: 2832548040
Category : Medical
Languages : en
Pages : 256

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Author: Warren Levinson
Publisher: McGraw Hill Professional
ISBN: 0071501991
Category : Medical
Languages : en
Pages : 656

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The most concise, comprehensive, and up-to-date medical microbiology & immunology review! Gives students the high-yield information they need to prepare for the USMLE Step 1 and course exams. Completely updated throughout, the new edition covers developments in HIV, hepatitis, smallpox, SARS, and more. Features case discussions, USMLE-style questions, and a USMLE-style practice exam.

Author: David Coleman
Publisher: Frontiers Media SA
ISBN: 2889458938
Category :
Languages : en
Pages : 141

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Book Description
Methicillin-resistant Staphylococcus aureus (MRSA) have been a major cause of healthcare-associated (HA) infection globally for several decades. During this time many distinct clones have emerged independently around the world, some of which have achieved pandemic status. More recently, community-associated (CA) and livestock-associated MRSA clones have also emerged, some of which have become established in hospitals and other healthcare facilities, and sometimes have displaced previously predominant HA clones. Importantly, MRSA can frequently exhibit resistance to a wide range of clinically relevant antibiotics, which limits treatment options and complicates patient management and outcomes. Investigating routes of transmission and spread of MRSA in healthcare facilities have conventionally been undertaken by combining available epidemiological information with data from DNA-based typing systems such as pulse-field gel electrophoresis typing, spa typing, multilocus sequence typing, and more recently, DNA microarray profiling. However, these approaches can frequently lack the discriminatory ability to differentiate between MRSA isolates in healthcare environments where a relatively small number of clones may predominate. The advent of high-throughput whole genome sequencing (WGS) over the last decade with the development of affordable, easy-to-use benchtop DNA sequencing platforms, associated sequencing chemistry and bioinformatics tools, has revolutionized studies of MRSA epidemiology and evolution. The significantly enhanced discriminatory power and resolution afforded by WGS has also provided hitherto unimaginable insights into the origins, emergence and factors that drive the evolution of specific MRSA clones. Furthermore, WGS has highlighted the very significant contributions of mobile genetic elements (MGEs) encoding virulence factors and resistance genes from coagulase-negative staphylococcal (CoNS) species to the emergence and evolution of MRSA. This Research Topic brings together a collection of original research articles and up-to-date reviews that highlight the significant impact WGS is having on our understanding of the epidemiology and routes of transmission of HA- and CA-MRSA in humans and the phylogenetics and evolution of specific MRSA clones. The Research Topic also highlights the impact that WGS is having on our understanding of antimicrobial resistance in MRSA by acquisition of MGEs and the role of specific CoNS species in the origins and evolution of particular MGEs that can promote the survival of MRSA following acquisition. Finally, the Research Topic highlights the immense potential impact of WGS technology in surveillance, rapid pathogen detection, identification of virulence factor profiles and antibiotic resistance genotypes, possibly from clinical samples directly.

Author: Judith Fraussen
Publisher: Frontiers Media SA
ISBN: 2889745651
Category : Medical
Languages : en
Pages : 232

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Author: Bernd Kaspers
Publisher: Academic Press
ISBN: 0123972728
Category : Medical
Languages : en
Pages : 456

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Book Description
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research