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Author: Michael A. Boudreau Publisher: ISA ISBN: 9781556179051 Category : Science Languages : en Pages : 356
Book Description
Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information systems, or automation engineer in the biopharmaceutical, brewing, or bio-fuel industry, this handy resource will help you define, develop, and apply a virtual plant, model predictive control, first-principle models, neural networks, and multivariate statistical process control. The synergistic knowledge discovery on bench top or pilot plant scale can be ported to industrial scale processes. This learning process is consistent with the intent in the Process Analyzer and Process Control Tools sections of the FDA_s Guidance for Industry PAT _ A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance. It states in the Process Analyzer section of the FDA_s guidance: _For certain applications, sensor-based measurements can provide a useful process signature that may be related to the underlying process steps or transformations. Based on the level of process understanding these signatures may also be useful for the process monitoring, control, and end point determination when these patterns or signatures relate to product and process quality._
Author: Michael A. Boudreau Publisher: ISA ISBN: 9781556179051 Category : Science Languages : en Pages : 356
Book Description
Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information systems, or automation engineer in the biopharmaceutical, brewing, or bio-fuel industry, this handy resource will help you define, develop, and apply a virtual plant, model predictive control, first-principle models, neural networks, and multivariate statistical process control. The synergistic knowledge discovery on bench top or pilot plant scale can be ported to industrial scale processes. This learning process is consistent with the intent in the Process Analyzer and Process Control Tools sections of the FDA_s Guidance for Industry PAT _ A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance. It states in the Process Analyzer section of the FDA_s guidance: _For certain applications, sensor-based measurements can provide a useful process signature that may be related to the underlying process steps or transformations. Based on the level of process understanding these signatures may also be useful for the process monitoring, control, and end point determination when these patterns or signatures relate to product and process quality._
Author: Claire Komives Publisher: John Wiley & Sons ISBN: 1119378303 Category : Science Languages : en Pages : 288
Book Description
Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies
Author: Ramon Vilanova Publisher: Springer Science & Business Media ISBN: 1447124251 Category : Technology & Engineering Languages : en Pages : 600
Book Description
The early 21st century has seen a renewed interest in research in the widely-adopted proportional-integral-differential (PID) form of control. PID Control in the Third Millennium provides an overview of the advances made as a result. Featuring: new approaches for controller tuning; control structures and configurations for more efficient control; practical issues in PID implementation; and non-standard approaches to PID including fractional-order, event-based, nonlinear, data-driven and predictive control; the nearly twenty chapters provide a state-of-the-art resumé of PID controller theory, design and realization. Each chapter has specialist authorship and ideas clearly characterized from both academic and industrial viewpoints. PID Control in the Third Millennium is of interest to academics requiring a reference for the current state of PID-related research and a stimulus for further inquiry. Industrial practitioners and manufacturers of control systems with application problems relating to PID will find this to be a practical source of appropriate and advanced solutions.
Author: Gregory K. McMillan Publisher: Momentum Press ISBN: 1606501712 Category : Technology & Engineering Languages : en Pages : 754
Book Description
Tuning and Control Loop Performance, Fourth Edition provides the knowledge to eliminate the misunderstandings, realize the difference between theoretical and industrial application of PID control, address practical difficulties, improve field automation system design, use the latest PID features, and ultimately get the best tuning settings that enables the PID to achieve its full potential. The proportional-integral-derivative (PID) controller is the heart of every control system in the process industry. Given the proper setup and tuning, the PID has proven to have the capability and flexibility needed to meet nearly all of industry’s basic control requirements. However, the information to support the best use of these features has fallen behind the progress of improved functionality. Additionally, there is considerable disagreement on the tuning rules that largely stems from a misunderstanding of how tuning rules have evolved and the lack of recognition of the effect of automation system dynamics and the incredible spectrum of process responses, disturbances, and performance objectives.
Author: Miodrag Darko Matovic Publisher: BoD – Books on Demand ISBN: 9535111051 Category : Technology & Engineering Languages : en Pages : 556
Book Description
This two-volume book on biomass is a reflection of the increase in biomass related research and applications, driven by overall higher interest in sustainable energy and food sources, by increased awareness of potentials and pitfalls of using biomass for energy, by the concerns for food supply and by multitude of potential biomass uses as a source material in organic chemistry, bringing in the concept of bio-refinery. It reflects the trend in broadening of biomass related research and an increased focus on second-generation bio-fuels. Its total of 40 chapters spans over diverse areas of biomass research, grouped into 9 themes.
Author: Hansjörg Hauser Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110278960 Category : Science Languages : en Pages : 718
Book Description
This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell lines, a survey of functional genomics for a better understanding of cell lines and processes, as well as advances in regulatory compliant upstream and downstream development. The book is an essential reference for all those interested in translational animal cell-based pharmaceutical biotechnology.
Author: George Buckbee (P.E.) Publisher: ISA ISBN: 9781934394250 Category : Business & Economics Languages : en Pages : 324
Book Description
A guide for engineers and designers new to the field of bio-pharmaceutical process control. For the experienced automation professional, it outlines the unique design and application issues for the bio-pharmaceutical industry. For those already familiar with this industry, it provides specific advice for automating these processes.
Author: Aidan O'dwyer Publisher: World Scientific ISBN: 1908978775 Category : Technology & Engineering Languages : en Pages : 623
Book Description
The vast majority of automatic controllers used to compensate industrial processes are PI or PID type. This book comprehensively compiles, using a unified notation, tuning rules for these controllers proposed from 1935 to 2008. The tuning rules are carefully categorized and application information about each rule is given. The book discusses controller architecture and process modeling issues, as well as the performance and robustness of loops compensated with PI or PID controllers. This unique publication brings together in an easy-to-use format material previously published in a large number of papers and books.This wholly revised third edition extends the presentation of PI and PID controller tuning rules, for single variable processes with time delays, to include additional rules compiled since the second edition was published in 2006./a
Author: Aidan O'Dwyer Publisher: Imperial College Press ISBN: 184816243X Category : Technology & Engineering Languages : en Pages : 623
Book Description
The vast majority of automatic controllers used to compensate industrial processes are PI or PID type. This book comprehensively compiles, using a unified notation, tuning rules for these controllers proposed from 1935 to 2008. The tuning rules are carefully categorized and application information about each rule is given. The book discusses controller architecture and process modeling issues, as well as the performance and robustness of loops compensated with PI or PID controllers. This unique publication brings together in an easy-to-use format material previously published in a large number of papers and books.This wholly revised third edition extends the presentation of PI and PID controller tuning rules, for single variable processes with time delays, to include additional rules compiled since the second edition was published in 2006.
Author: Michael A. Boudreau
Author: Michael A. Boudreau
Author: Claire Komives
Author: Ramon Vilanova
Author: Gregory K. McMillan
Author: Miodrag Darko Matovic
Author: Hansjörg Hauser
Author: George Buckbee (P.E.)
Author: Gregory McMillan
Author: Aidan O'dwyer
Author: Aidan O'Dwyer