Author: Scott Jeffrey PollackPublisher:
ISBN:
Category :
Languages : en
Pages : 640
Book Description
New Approaches to Catalytic Antibodies
Author: Scott Jeffrey PollackPublisher:
ISBN:
Category :
Languages : en
Pages : 640
Book Description
Catalytic Antibodies
Author: Sudhir PaulPublisher: Karger Medical and Scientific Publishers
ISBN: 3805570996
Category : Medical
Languages : en
Pages : 172
Book Description
This volume addresses fundamental questions concerning the immunological genesis of the catalytic activity in antibodies, its relationship with classical antigen binding activity, and the biochemical mechanisms involved in catalysis. The contents reflect three main challenges in the field, i.e. to delineate the biological functions of catalytic antibodies in autoimmune disease; to isolate therapy-grade antibody catalysts with sufficient specificity and turnover to permit rapid removal of microbial and tumor antigens; and to develop immunogens that recruit immature catalyst-producing B cells into the clonal selection pathway and induce adaptive improvements of the catalytic function. Well-edited and up-to-date, this book reviews the current knowledge in the field and explores ways by which natural and engineered catalytic activities can be harnessed for medical applications. It should therefore be of special interest to immunologists, biochemists, biotechnologists, rheumatologists and pathologists.
Catalytic Antibodies
Author: Derek J. ChadwickPublisher: John Wiley & Sons
ISBN: 0470514116
Category : Science
Languages : en
Pages : 270
Book Description
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.
Efficient Catalytic Antibodies
Author: Chris M. AronchickPublisher:
ISBN:
Category : Enzymes
Languages : en
Pages : 142
Book Description
Catalytic Antibodies
Author: David Young JacksonCatalytic Antibodies
Author: Ehud KeinanPublisher: Wiley-VCH
ISBN: 9783527306886
Category : Science
Languages : en
Pages : 0
Book Description
Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: * theoretical aspects of structure, mechanism and kinetics * practical considerations, from immunization techniques to screening methods * in vitro evolution and other modern approaches * applications from organic synthesis to medical uses. Backed by the leading authorities in antibody catalysis, this is the first book to provide such comprehensive coverage and constitutes a prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.
Molecularly Imprinted Catalysts
Author: Songjun LiPublisher: Elsevier
ISBN: 012801444X
Category : Technology & Engineering
Languages : en
Pages : 312
Book Description
Molecularly Imprinted Catalysts: Principle, Synthesis, and Applications is the first book of its kind to provide an in-depth overview of molecularly imprinted catalysts and selective catalysis, including technical details, principles of selective catalysis, preparation processes, the catalytically active polymers themselves, and important progress made in this field. It serves as an important reference for scientists, students, and researchers who are working in the areas of molecular imprinting, catalysis, molecular recognition, materials science, biotechnology, and nanotechnology. Comprising a diverse group of experts from prestigious universities and industries across the world, the contributors to this book provide access to the latest knowledge and eye-catching achievements in the field, and an understanding of what progress has been made and to what extent it is being advanced in industry. The first book in the field on molecularly imprinted catalysts (MIPs) Provides a systematic background to selective catalysis, especially the basic concepts and key principles of the different MIP-based catalysts Features state-of-the art presentation of preparation methods and applications of MIPs Written by scientists from prestigious universities and industries across the world, and edited by veteran researchers in molecular imprinting and selective catalysis
New Directions in Catalytic Antibodies
Author: Grace Reiko NakayamaPublisher:
ISBN:
Category :
Languages : en
Pages : 614
Book Description
New Routes of Catalytic Antibodies
Author: Kevan Michael ShokatPublisher:
ISBN:
Category :
Languages : en
Pages : 572
Book Description
Designing Antibodies
Author: Ruth MayforthPublisher: Academic Press
ISBN: 0323160026
Category : Medical
Languages : en
Pages : 217
Book Description
Designing Antibodies provides a compilation of research in the design of antibodies. It describes the techniques used in antibody design, the kinds of antibodies generated through modern techniques, and their applications in medicine and science. The book begins with an overview of the humoral immune system and of antibody structure, function, and biosynthesis, which sets the stage for the subsequent discussions of developments in antibody technology. The remaining chapters discuss the making of monoclonal antibodies; the design of antibodies for human therapy; the connection of antibodies (either chemically or genetically) to other potentially therapeutic effector molecules such as toxins, enzymes, or even an antibody of another specificity; idiotypes and anti-idiotypic antibodies; and the ability of antibodies to functionally mimic enzymes and mediate catalysis. It is hoped that, in addition to illustrating the progress of research in antibody design, the various creative and innovative approaches reviewed in this book will be modified or will stimulate new ideas that will spur the research and application of designer antibodies.