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Author: Igor Grant Publisher: Oxford University Press, USA ISBN: 9780195072259 Category : Clinical neuropsychology Languages : en Pages : 414
Book Description
The human immunodeficiency virus (HIV) commonly enters the central nervous system, disturbs brain function, and ultimately results in serious brain damage. The most dangerous manifestation of this infection of the brain is HIV-associated dementia, which includes extreme memory loss, slowness in thinking, disorientation, and social incapacity. Most persons who are HIV-infected do not develop severe dementia; however, perhaps 50% of those with AIDS and a smaller proportion of HIV-infected carriers suffer from more subtle brain disorders that can be revealed by proper neuropsychological testing. This ground-breaking volume is the first to summarize the current state of knowledge about the neurocognitive disorders associated with HIV-1 infection. With contributions from leading authorities in the field, the book fully discusses the prevalence, qualitative features, natural course, and effects of neuropsychological impairments in persons with HIV infection. Neuropsychological data are related to findings from studies of brain imaging, neuropathology, and the effects of antiretroviral treatments. This critical work will be essential for neuropsychologists, infectious disease physicians, neurologists, and all those involved in AIDS research and treatment.
Author: Igor Grant Publisher: Oxford University Press, USA ISBN: 9780195072259 Category : Clinical neuropsychology Languages : en Pages : 414
Book Description
The human immunodeficiency virus (HIV) commonly enters the central nervous system, disturbs brain function, and ultimately results in serious brain damage. The most dangerous manifestation of this infection of the brain is HIV-associated dementia, which includes extreme memory loss, slowness in thinking, disorientation, and social incapacity. Most persons who are HIV-infected do not develop severe dementia; however, perhaps 50% of those with AIDS and a smaller proportion of HIV-infected carriers suffer from more subtle brain disorders that can be revealed by proper neuropsychological testing. This ground-breaking volume is the first to summarize the current state of knowledge about the neurocognitive disorders associated with HIV-1 infection. With contributions from leading authorities in the field, the book fully discusses the prevalence, qualitative features, natural course, and effects of neuropsychological impairments in persons with HIV infection. Neuropsychological data are related to findings from studies of brain imaging, neuropathology, and the effects of antiretroviral treatments. This critical work will be essential for neuropsychologists, infectious disease physicians, neurologists, and all those involved in AIDS research and treatment.
Author: Lucette A. Cysique Publisher: Springer Nature ISBN: 3030807592 Category : Medical Languages : en Pages : 548
Book Description
This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com
Author: Glenn E. Smith Publisher: APA Handbooks in Psychology(r) ISBN: 9781433828799 Category : Psychology Languages : en Pages : 712
Book Description
The APA Handbook of Dementia addresses assessment, comorbidity, evaluation, and treatment of various forms of dementia. The handbook reviews common dementias including Alzheimer's disease, Lewy body disease, vascular dementia, frontotemporal dementia, and other less common dementias. It is organized into sections discussing diagnosis, epidemiology, and neurobiology (including neuropathology and neuroimaging); assessment, including cultural issues, methodology, and neuropsychology; and primary, secondary, and tertiary intervention strategies. The handbook is intended as a resource for all psychologists and other health professionals that serve persons and families impacted by neurodegenerative disease.
Author: Guoku Hu Publisher: Elsevier ISBN: 0323997457 Category : Psychology Languages : en Pages : 654
Book Description
HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection. - Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities - Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms - Examines animal models for studying HAND, including macaque and rodent models - Presents insights into epigenetic regulation and signaling pathways implicated in HAND - Covers prevention, therapeutic strategies, and diagnostic approaches
Author: Michael Oldstone Publisher: Springer ISBN: 9783642796586 Category : Medical Languages : en Pages : 279
Book Description
The National Institute of Mental Health (NIMH) AIDS Program is the fourth largest acquired immune deficiency syndrome (AIDS) program within the National Institutes of Health (NIH). Since 1983, our program's contributions have concentrated on two major areas. The first has been to develop effective strategies to prevent or reduce behaviors that place individuals at risk for human immunodeficiency virus type 1 (HIV-1) infection. The second has been to support and foster research to enhance our understanding of the profound impact of H IV-1 infection on the central nervous system (eNS). The brain appears to be a prime target of the virus and may serve as a reservoir for the virus. Post mortem examination of brain tissue has provided evidence of eNS cell damage in 80%-90% of people who die with AIDS. For about 10%-20% of people with AI DS, mild neuropsychological symptoms are the first signs of the disease. Approximately 20% of individuals infected with HIV-1 develop AIDS dementia complex. The symptoms include apathy, difficulty concentrat ing, irritability, depression, and personality changes. In the later stages of the disease, people may experience psychiatric disor ders. Death usually occurs within 6 months of the appearance of those more severe symptoms. Up to 90% of children infected with H IV-1 experience attention and concentration difficulties and often experience neurodevelopmental delay or regression over time.
Author: Michael Oldstone Publisher: Springer ISBN: 9783540591177 Category : Medical Languages : en Pages : 279
Book Description
The National Institute of Mental Health (NIMH) AIDS Program is the fourth largest acquired immune deficiency syndrome (AIDS) program within the National Institutes of Health (NIH). Since 1983, our program's contributions have concentrated on two major areas. The first has been to develop effective strategies to prevent or reduce behaviors that place individuals at risk for human immunodeficiency virus type 1 (HIV-1) infection. The second has been to support and foster research to enhance our understanding of the profound impact of H IV-1 infection on the central nervous system (eNS). The brain appears to be a prime target of the virus and may serve as a reservoir for the virus. Post mortem examination of brain tissue has provided evidence of eNS cell damage in 80%-90% of people who die with AIDS. For about 10%-20% of people with AI DS, mild neuropsychological symptoms are the first signs of the disease. Approximately 20% of individuals infected with HIV-1 develop AIDS dementia complex. The symptoms include apathy, difficulty concentrat ing, irritability, depression, and personality changes. In the later stages of the disease, people may experience psychiatric disor ders. Death usually occurs within 6 months of the appearance of those more severe symptoms. Up to 90% of children infected with H IV-1 experience attention and concentration difficulties and often experience neurodevelopmental delay or regression over time.
Author: Jonathan DeRight Publisher: Springer Nature ISBN: 3030853721 Category : Psychology Languages : en Pages : 335
Book Description
The goal of this book is to provide brief-but-comprehensive information that can aid in rapid differential diagnosis and allow for more thorough follow-up if needed. This guide is intended to fit easily into the pocket of a lab coat or on your desk, giving readers an efficient way to find information about a specific disease or disorder to prepare for an upcoming case. The book is divided into two parts: Part 1 involves general psychometric and reference information including score classifications, formulas for score conversion, likelihood chaining, and reliable change, psychometric data for stand-alone and embedded PVTs, and the effects of common medications on cognition. Part 2 of the book is organized alphabetically by disease or disorder to promote quick searching, and each chapter provides straightforward information including definitions, subtypes, etiology, epidemiology, course, diagnostic criteria, expectations for test results, and links to more comprehensive sources. Whenever possible, information is gathered through up-to-date literature and high quality pubilcations such as systematic reviews or meta-analyses. Helpful references are provided for more extensive follow-up or further reading.
Author: Thomas D. Marcotte Publisher: Guilford Publications ISBN: 1462548903 Category : Psychology Languages : en Pages : 760
Book Description
The go-to resource for assessing and predicting functional abilities in persons with brain injury or cognitive decline has now been revised and expanded to reflect significant advances in the field. With a focus on key real-world capacities--independent living, vocational functioning, medication management, and driving--leading experts explore how individuals go about their daily lives, where and why disruptions occur, and potential opportunities for improving function. Strategies for direct assessment are reviewed, from standard neuropsychological tests to multimodal approaches and technology-based tools. Chapters also provide functional assessment guidance for specific neurological and psychiatric conditions: dementia, traumatic brain injury, depression, schizophrenia, and others. New to This Edition *Incorporates over a decade of technological and methodological innovations. *Chapter on theories and models of everyday functioning. *Chapters on naturalistic assessment, wearable sensors, ambulatory assessment, and virtual-reality-based tools. *Practical clinical implications are highlighted throughout.
Author: Alireza Minagar Publisher: Nova Publishers ISBN: 9781594546105 Category : Medical Languages : en Pages : 280
Book Description
During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.
Author: Igor Grant
Author: Igor Grant
Author: Lucette A. Cysique
Author: Glenn E. Smith
Author: Guoku Hu
Author: 
Author: Michael Oldstone
Author: Michael Oldstone
Author: Jonathan DeRight
Author: Thomas D. Marcotte
Author: Alireza Minagar