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Neural Mechanisms of Anesthesia

Neural Mechanisms of Anesthesia PDF Author: Joseph E. Antognini
Publisher: Springer Science & Business Media
ISBN:
Category : Health & Fitness
Languages : en
Pages : 498

Book Description
Investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. They review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. This text draws together and reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free of undesirable side effects.

Neural Mechanisms of Anesthesia

Neural Mechanisms of Anesthesia PDF Author: Joseph E. Antognini
Publisher: Springer Science & Business Media
ISBN:
Category : Health & Fitness
Languages : en
Pages : 498

Book Description
Investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. They review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. This text draws together and reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free of undesirable side effects.

Anesthetic Pharmacology

Anesthetic Pharmacology PDF Author: Alex S. Evers
Publisher: Cambridge University Press
ISBN: 1139497022
Category : Medical
Languages : en
Pages : 2902

Book Description
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Neural Mechanisms of Anesthesia

Neural Mechanisms of Anesthesia PDF Author: Joseph E. Antognini
Publisher: Springer Science & Business Media
ISBN: 1592593224
Category : Medical
Languages : en
Pages : 464

Book Description
Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. These distinguished experts review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.

Sleep and Anesthesia

Sleep and Anesthesia PDF Author: Axel Hutt
Publisher: Springer Science & Business Media
ISBN: 1461401739
Category : Medical
Languages : en
Pages : 268

Book Description
Sleep and anesthesia resemble in many ways at a first glance. The most prominent common feature of course is the loss of consciousness, i.e. the loss of awareness of external stimuli. However a closer look at the loss of consciousness reveals already a difference between sleep and anesthesia: anesthesia is induced by an anesthetic drug whereas we may fall asleep without external cause. Other questions may arise about the difference of the two effects: do we dream during surgery under anesthesia, do we feel pain during sleep? Essentially, we may ask: what is common and what are the differences between sleep and anesthesia? To answer these questions, we may take a look at the neural origin of both effects and the involved physiological pathways. In which way do they resemble? Moreover, we ask what are the detailed features of normal sleep and general anesthesia as applied during surgery and which features exist in both phenomena? If yes in which way? To receive answers to these questions, it is necessary to consider several experimental techniques that reveal underlying neural mechanisms of sleep and anesthesia. Moreover, theoretical models of neural activity may model both phenomena and comes up with predictions or even theories on the underlying mechanisms. Such models may attack several different description levels, from the microscopic level of single neurons to the macroscopic level of neural populations. Such models may give deeper insight into the phenomena if their assumptions are based on experimental findings and their predictions can be compared to experimental results. This comparison step is essential for valuable theoretical models. The book is motivated by two successful workshops on anesthesia and sleep organized during the Computational Neuroscience Conferences in Toronto in 2007 and in Berlin 2009. It aims to cover all the previous aspects with a focus on the link to experimental findings. It elucidates important issues in theoretical models that at the same time reflect some current major research interests. Moreover it considers some diverse issues which are very important to get an overview of the fields. For instance, the book discusses not only neural activity in the brain but also the effects of general anesthesia on the cardio-vascular system and the spinal cord in the context of analgesia. In addition, it considers different experimental techniques on various spatial scales, such as fMRI and EEG-experiments on the macroscopic scale and single neuron and LFP-measurements on the microscopic scale. In total all book chapters reveal aspects of the neural correlates of sleep and anesthesia motivated by experimental data. This focus on the neural mechanism in the light of experimental data is the common feature of the topics and the chapters. In addition, the book aims to clarify the shared physiological mechanisms of both phenomena, but also reveal their physiological differences.

Essential Clinical Anesthesia

Essential Clinical Anesthesia PDF Author: Charles Vacanti
Publisher: Cambridge University Press
ISBN: 1139498401
Category : Medical
Languages : en
Pages : 1191

Book Description
The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Neural Blockade in Clinical Anesthesia and Management of Pain

Neural Blockade in Clinical Anesthesia and Management of Pain PDF Author: Michael J. Cousins
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 1220

Book Description


The Neuroethics of Memory

The Neuroethics of Memory PDF Author: Walter Glannon
Publisher: Cambridge University Press
ISBN: 1107131979
Category : Law
Languages : en
Pages : 245

Book Description
Provides a thematically integrated analysis and discussion of neuroethical questions about memory capacity, content, and interventions.

Clinical Electroencephalography

Clinical Electroencephalography PDF Author: Oriano Mecarelli
Publisher: Springer
ISBN: 3030045730
Category : Medical
Languages : en
Pages : 822

Book Description
This book describes the developments and improvements in electroencephalography (EEG). In recent years, digital technology has replaced analog equipments, and it is now possible to easily record and store EEG tracings and to quickly recall previously acquired material for subsequent analysis. In addition, not only static figures, but also electronic supplementary materials can be included in books, enabling EEGs to be viewed in real-time. In clinical practice, EEG still represents the most important functional examination in the study CNS development and its anatomical and physiological integrity throughout life. In the pathological context, EEG provides indispensable diagnostic information for classification of epileptic syndromes, and it is also valuable in all the other CNS diseases (infectious, cerebrovascular, neurodegenerative, etc). Furthermore, monitoring EEG can be widely used in emergency settings, such as emergency departments or intensive care units. In comatose patients, EEG provides information regarding prognosis and evaluation of the sedative effect of anesthetic drugs. Written by a group of leading national and international experts, it offers a substantial, yet practical, EEG compendium, which serves as a reference resource for physicians and neurodiagnostic technologists as well as physicians-in-training, researchers, practicing electroencephalographers and students.

General Anesthesia Research

General Anesthesia Research PDF Author: Marco Cascella
Publisher: Humana
ISBN: 9781493998906
Category : Medical
Languages : en
Pages : 0

Book Description
This book explores several aspects of the research in the field of general anesthesia, including mechanisms of action of inhaled and intravenous hypnotic agents; the anesthetics-induced neurotoxicity in children and elderly; features and physiopathology of postoperative cognitive side effects; and findings from preclinical research focused on the recognition of potential links between anesthetics and cancer cell biology. Furthermore, chapters in this book cover technical topics such as preoperative monitoring of autonomic nervous activity; EEG based monitoring of general anesthesia; monitoring cerebral oximetry by near infrared spectroscopy; pharmacological issues of anesthesia interest; and optimization of perioperative course through the latest techniques such as the opioid-free anesthesia. Finally, this book offers a comprehensive and up-to-date discussion on the phenomenon of general anesthesia awareness and its potential psychological sequelae. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, General Anesthesia Research is a valuable resource for novice and expert anesthesiologists who want to learn more about the important advances made in this developing field.

Opioids in Anesthesia

Opioids in Anesthesia PDF Author: Fawzy G. Estafanous
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 352

Book Description