Need to know about Optical Coherence Tomography (OCT): A Novel, Promising Imaging Modality, for examining Coronary arteries having 10-fold higher resolution than IVUS. PDF Download

Author: Dr. Hakim. K. Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 50

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Book Description
Need to know about Optical Coherence Tomography (OCT): A Novel, Promising Imaging Modality, for examining Coronary arteries having 10-fold higher resolution than IVUS. In cardiology, OCT is an optical analog of for IVUS examination is replaced intravascular ultrasound (IVUS), used to examine the coronary arteries. Ultrasound employed by near-infrared light with a wavelength of about 1,300 nm, which is absorbed by red blood cells, water, lipids, and protein at relatively low levels. Through a rotating glass fiber-optic system, coherent infrared light can be directed and reflected within the tissue to create a detailed tissue image with extraordinarily high resolution, and IVUS-like cross-sectional tomographic images can be obtained. OCT and IVUS differ in several respects. The resolution of OCT (to 10-20 µm) is about 10-fold higher than that of IVUS (to 100-150 µm), but the maximum depth of tissue penetration is lower with OCT (1-2 mm) than with IVUS (4-8 mm). Another important difference is related to the strong attenuation of light by blood, which originates from two sources: absorption by: · haemoglobin and · scattering by red blood cells. To examine coronary arteries, blood must first be removed during an OCT examination to eliminate massive scattering of light by red blood cells. Thus, an attempt has been made to discuss the role of OTC in Cardiology along with several relevant Tables and Illustrations for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London

Author: Hiram G. Bezerra
Publisher: CRC Press
ISBN: 1351667688
Category : Medical
Languages : en
Pages : 305

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Book Description
This book, written by premier authors in the field of OCT intravascular imaging, covers the best practices for using OCT to provide high resolution cross-sectional viewing for atherosclerotic plaque assessment, stent strut coverage and apposition, assessment in stent restenosis evaluation, and PCI guide and optimization. Fully illustrated thorughout in a handy, cath-lab side handbook supplemented by online movie clips, OCT Made Easy includes case studies, angiography, CT correlations, and simple techniques for getting the best image.

Author: Evelyn Regar
Publisher: CRC Press
ISBN: 0203931564
Category : Medical
Languages : en
Pages : 384

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Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT h

Author: Jiechen Yin
Publisher:
ISBN: 9781124881256
Category :
Languages : en
Pages : 126

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Book Description
Optical coherence tomography (OCT) is a noninvasive, noncontact imaging modality that uses coherent gating to obtain high-resolution cross-sectional images of the microstructure of biological tissues. Recently, OCT has been considered as a promising technique for intravascular imaging, since it provides direct visualization of vessel walls with resolutions of 1-2 orders higher than intravascular ultrasound (IVUS). However, there are two major drawbacks for OCT: limited penetration depth makes it difficult to image the whole depth of atherosclerotic plaques and clearance of blood is required since the presence of blood can seriously attenuate OCT signals. OCT and ultrasound (US) are complementary in the application of intravascular imaging. This research focuses on the development of an integrated OCT-US system for the application of intravascular imaging. By combining the two imaging modalities, the system is capable of offering simultaneous OCT and ultrasound images in real-time, thus allowing for images with both high resolution and a deep imaging depth which will significantly improve diagnostic accuracy in the detection of atherosclerosis. OCT-US probes that combine OCT optical components and US transducers have been developed. Different probe designs have been realized based on different applications; and the latest version of the miniature design aimed at human coronary artery imaging has a maximum outer diameter of only 0.69mm. A rotary joint that combines a fiber optic rotary joint and electrical slip ring has been developed, so that both optical and electrical signals can be transmitted between the stationary and rotary parts of the system. The integrated imaging system provides real-time simultaneous OCT and US data acquisition, processing and image display by using a single two-channel data acquisition board and a home-developed OCT-US program. In vitro human coronary specimen imaging and in vivo animal studies have been performed to demonstrate the feasibility of our OCT-US system in the application of intravascular imaging. Last but not least, a 3-dimensional high speed endoscopic OCT system has been developed for the application of airway imaging. In vivo animal studies of smoke-induced early airway injury were performed using this system. Image processing software has been successfully developed for motion artifact removal, image reconstruction and quantitative analysis of airway thickness.

Author: Ik-Kyung Jang
Publisher: Springer Nature
ISBN: 3030257118
Category : Medical
Languages : en
Pages : 198

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Book Description
This heavily revised second edition comprehensively reviews the use of optical coherence tomography (OCT) in cardiovascular practice. It provides detailed guidance on how to properly interpret OCT images and successfully utilise it in daily clinical practice Chapters cover the development and physics associated with OCT, relevant interpretation skills, OCT imaging artifacts, plaque erosion, bioabsorbable stent, the detection of vulnerable plaque, and the use of OCT imaging in unison with other modalities such as phase contrast imaging (PCI). Areas of potential future development are also covered Cardiovascular OCT Imaging enables interventional cardiologists and cardiologists to quickly become both familiar and develop a detailed understanding of this technology to improve patient care and treatment outcome. It is a valuable reference for all practising and trainee medical professionals in cardiology, and in particular those who specialize in interventional cardiology.

Author: Zhao Wang
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 137

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Book Description
Coronary artery disease (CAD) is the leading cause of death in the world. Most acute coronary events such as heart attacks and sudden deaths are due to the rupture of atherosclerotic plaques inside the arteries. Intravascular Optical Coherence Tomography (IVOCT), a high resolution (10-20μm) imaging modality that performs cross-sectional imaging of coronary arteries by measuring echoes of backscattered light, is rapidly becoming a promising imaging modality for diagnosis of CAD. Compared to alternative technologies such as intravascular ultrasound (IVUS), IVOCT with better resolution allows characterization of atherosclerotic plaques and evaluation of coronary stenting with unprecendented details. Currently, analysis of OCT images has been typically conducted manually in an extremely time-consuming manner. The aim of this PhD dissertation is to develop advanced image processing algorithms and software to automate the task and thereby reduce the image analysis time drastically. In this dissertation, we developed image analysis algorithms for a variety of IVOCT applications, including: (1) 3-D lumen boundary segmentation, (2) Guide wire artifact segmentation, (3) Automated calibration of IVOCT images, (4) Volumetric quantification of fibrous caps, (5) Automated segmentation of calcified plaques, (6) Automated quantification of macrophages and (7) Automated stent analysis, covering almost all the essential tasks performed in the Cardiovascular Imaging Core Laboratories (Core Lab). The algorithms we have developed have been extensively validated using a large number of data sets, and are robust to be used for real world clinical data analysis. Furthermore, we developed the prototype software OCTivat (intravascular OCT image visualization and analysis toolkit) for IVOCT image visualization and analysis, and it is being used by the interventional cardiologists in the Core Lab at the University Hospitals Case Medical Center. These image analysis methods, as well as OCTivat, can reduce the IVOCT image analysis time from tens of hours down to minutes. This may enable large clinical trial analysis and real-time feedback during clinical procedures, and may potentially improve patient care.

Author: Annapoorna Kini
Publisher: Springer
ISBN: 3319626663
Category : Medical
Languages : en
Pages : 109

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Book Description
This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in clinical practice in Mount Sinai to assess the disease, select appropriate treatment, and evaluate complications and results. Each case includes a brief clinical history, procedure summary, angiography and OCT images, including video material, and a discussion of how OCT affected the clinical decision-making process.

Author:
Publisher: ScholarlyEditions
ISBN: 1464994358
Category : Medical
Languages : en
Pages : 388

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Book Description
Advances in Diagnostics and Screening Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Diagnostics and Screening. The editors have built Advances in Diagnostics and Screening Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnostics and Screening in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Diagnostics and Screening Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author: Wing-Ching Wendy Cheung
Publisher:
ISBN: 9781361019276
Category :
Languages : en
Pages :

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Book Description
This dissertation, "To Evaluate the Effectiveness and Safety of Optical Coherence Tomography (OCT) in Percutaneous Coronary Intervention (PCI): a Systematic Review" by Wing-ching, Wendy, Cheung, 張穎清, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Background: Coronary heart disease is a common cause of death in Hong Kong. Percutaneous coronary intervention (PCI) is widely used to treat coronary vessel disease nowadays. Optical coherence tomography (OCT) is a high-resolution imaging technique which is suggested as a useful guide during PCI. It is getting more frequent to use OCT to image coronary arteries. There is a concern of the effectiveness and safety of this device. Aims: We performed a qualitative systematic review to evaluate the effectiveness and safety of OCT in PCI. Methods: A review of literatures published on or before Feb 2015 from online database identified 21 relevant studies for our review. Design: We carried out the synthesis using the meta-ethnography. Results: No complication was found to be correlated with OCT used. OCT yield a higher success rate than IVUS. Significant correlation was found between OCT and IVUS measured stent length. No significant difference were found between OCT and IVUS measured lumen and stent area. Conclusions: OCT is feasible and safe to use and it is a useful coronary imaging tool to use in PCI. More multicenter randomized control trails should be conducted to assess the effectiveness and weakness of OCT. Subjects: Optical coherence tomography Coronary heart disease - Treatment

Author: Michael Wang
Publisher: BoD – Books on Demand
ISBN: 1789842611
Category : Science
Languages : en
Pages : 226

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Book Description
Optical coherence tomography (OCT) is a promising non-invasive non-contact 3D imaging technique that can be used to evaluate and inspect material surfaces, multilayer polymer films, fiber coils, and coatings. OCT can be used for the examination of cultural heritage objects and 3D imaging of microstructures. With subsurface 3D fingerprint imaging capability, OCT could be a valuable tool for enhancing security in biometric applications. OCT can also be used for the evaluation of fastener flushness for improving aerodynamic performance of high-speed aircraft. More and more OCT non-medical applications are emerging. In this book, we present some recent advancements in OCT technology and non-medical applications.